Catalysis Mechanisms in Enzymes

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What is acid-base catalysis primarily involved with?

Phosphorylation
Hydrolysis
Proton transfer (correct)
Electron transfer

What process is involved in acid-base catalysis?

Electrostatic attraction
Van der Waals forces
Hydrogen bonding
Proton transfer (correct)

Which of the following is NOT a feature of acid-base catalysis?

Covalent bonding
Redox reaction (correct)
Proton transfer
Electron pairing

What is the primary mechanism of acid-base catalysis?

Proton transfer (A) Signup and view all the answers

What is the topic discussed in the lecture?

Covalent Catalysis (D) Signup and view all the answers

Which of the following is a type of catalysis that involves proton transfer?

Acid-base catalysis (C) Signup and view all the answers

What is the classification of the catalysis discussed in the lecture?

Covalent Catalysis (C) Signup and view all the answers

What is the name of the lecture series?

W Lecture Series (D) Signup and view all the answers

What is the subtitle of the lecture?

عرض الشرائع حركات B.Covalent Catalysis (A) Signup and view all the answers

What is the abbreviation 'B.C.' likely to stand for?

Bonding Covalent (C) Signup and view all the answers

What is a typical electrophilic center in a substrate?

Phosphoryl group (A) Signup and view all the answers

Which group is also an electrophilic center in a substrate?

Acyl group (B) Signup and view all the answers

What is another type of electrophilic center in a substrate?

Glycosyl group (C) Signup and view all the answers

Which of the following is not a typical electrophilic center in a substrate?

Alkyl group (C) Signup and view all the answers

What are the three types of electrophilic centers mentioned?

Phosphoryl, Acyl, and Glycosyl (A) Signup and view all the answers

What is one of the possible mechanisms of catalysis?

Approximation, bringing reactants in close proximity (D) Signup and view all the answers

What is the role of an enzyme in catalysis?

To bring reactants close together to facilitate the reaction (B) Signup and view all the answers

What is the result of an enzyme catalyzing a reaction?

The reaction rate increases (B) Signup and view all the answers

What is the purpose of an enzyme's active site?

To bind with reactants (B) Signup and view all the answers

What is the mechanism of catalysis that involves the enzyme changing the reaction environment?

Acid-base catalysis (A) Signup and view all the answers

What is the primary function of electrostatic stabilization?

To shield negative charges (D) Signup and view all the answers

What is the significance of electrostatic stabilization in biological systems?

It stabilizes the structure of biological molecules (B) Signup and view all the answers

What is the outcome of electrostatic stabilization in acid-base catalysis?

Shielding of negative charges (D) Signup and view all the answers

What is the role of electrostatic stabilization in enzyme-catalyzed reactions?

To stabilize the transition state (C) Signup and view all the answers

What is the significance of negative charges in electrostatic stabilization?

They need to be shielded for optimal catalysis (D) Signup and view all the answers