Cardiovascular System: Physiology and Pathophysiology

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16 Questions

What is the main cause of the contraction of cardiac muscle (systole)?

Closing of voltage gated Ca+2 channels

What is the process that results in the return of ions to their previous resting state in cardiac muscle?

Repolarization

What causes hyperpolarization in cardiac muscle?

Influx of anions (Cl– ions) through chloride channels

What does the refractory period refer to in excitable membranes?

The amount of time it takes for a membrane to be ready to respond to a second stimulus

From where does the cardiac electric impulse originate in the heart?

SA node (Pacemaker)

What role does the AV node play in the heart's conductive system?

Allows passage of the electric impulse slowly (AV nodal delay)

What is responsible for transmitting the cardiac electric impulse from the AV node to the right and left ventricles?

Right and left bundle branches

What is the final step in the heart's conductive system?

Purkinje fibers distributing impulse to all cells

What is the primary characteristic of the cardiac muscle?

Auto-rhythmicity

Which cells in the heart can generate action potential spontaneously?

SA node and AV node

What is the normal pacemaker of the heart?

SA node

What factor can cause an increase in heart rate (↑HR)?

Sympathetic stimulation

During which phase of action potential does depolarization occur?

Phase 0

What causes a large influx of sodium ions inside the cardiac cell during depolarization?

Opening of voltage-gated sodium channels

Which type of stimulation can lead to a decrease in heart rate (↓HR)?

Parasympathetic stimulation

What is the primary function of the SA node in the heart?

Generating action potential spontaneously

Test your knowledge of the components and characteristics of the cardiovascular system, including the heart, blood vessels, and blood circulation. Explore the automatic, rhythmic, excitable, conductive, and contractile features of the cardiac muscle.

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