Cardiovascular System & Haematology: Stable Ischemic Heart Disease
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Questions and Answers

What are the symptoms of Stable Ischemic Heart Disease (SIHD)?

Neck or jaw pain, shoulder or arm pain, fast heartbeat, shortness of breath, nausea and vomiting, sweating, fatigue

What are some risk factors for Ischemic Heart Disease?

  • High HDL levels
  • Hypertension (correct)
  • Alcohol abuse (correct)
  • Age & Female
  • Strict glycemic control is beneficial for patients with advanced Chronic Kidney Disease (CKD).

    False

    Behavioral modification therapy for Ischemic Heart Disease includes patient education, diet, physical activity, and smoking ______________.

    <p>cessation</p> Signup and view all the answers

    What are the symptoms of stable ischemic heart disease (SIHD)?

    <p>Angina Pectoris, neck or jaw pain, shoulder or arm pain, fast heartbeat, shortness of breath, nausea, vomiting, sweating, fatigue</p> Signup and view all the answers

    What are common risk factors for the development of ischemic heart diseases?

    <p>Age, male gender, and diabetes mellitus</p> Signup and view all the answers

    Behavioral modification therapy is an essential component for all risk factors associated with ischemic heart diseases.

    <p>True</p> Signup and view all the answers

    What is the primary purpose of vasculoprotective therapy in the treatment of ischemic heart diseases?

    <p>To reduce the risk of future cardiovascular events</p> Signup and view all the answers

    Which pharmacotherapy is considered essential for alleviating acute symptoms of myocardial ischemia?

    <p>Nitrates</p> Signup and view all the answers

    Study Notes

    Stable Ischemic Heart Disease (SIHD)

    • SIHD is characterized by ischemia (reduced blood flow) but not infarction (heart tissue death)

    Symptoms of SIHD

    • Angina pectoris or stable angina
    • Neck or jaw pain
    • Shoulder or arm pain
    • Fast heartbeat
    • Shortness of breath (on exertion)
    • Nausea and vomiting
    • Sweating
    • Fatigue
    • Exclude: new chest pain, chest pain at rest, or positive biomarkers

    Risk Factors for SIHD

    • Atheroma in one or more coronary arteries
    • BMI > 27.5 kg/m²
    • Age and male sex
    • Diabetes mellitus
    • Smoking
    • Family history
    • Á LDL and/or â HDL
    • Hypertension
    • Alcohol abuse

    Risk Stratification

    • 2-3 modalities recommended for stratification

    Treatment Outcomes and Approach

    • Prevent acute coronary syndrome (MI) and death
    • Alleviate acute symptoms of myocardial ischemia
    • Prevent recurrent symptoms of myocardial ischemia
    • Prevent disease progression
    • Avoid or minimize adverse treatment effects

    Pharmacotherapy

    • Vasculoprotective therapy:
      • Behavioral modification therapy for all risks
      • Risk factor modification (ACEIs and statins)
      • Antiplatelet therapy
    • Anti-ischemic pharmacotherapy:
      • Beta blockers, nitrates, calcium-channel blockers, and trimetazidine
      • Others: ivabradine, nicorandil, ranolazine, SGLT2, and GLP-1RA

    Myocardial Revascularization

    • Must be done in high-risk patients

    Special Populations

    • Chronic kidney disease:
      • Limited data on efficacy and role of pharmacotherapy and revascularization
      • Importance of lifestyle modification, good glycemic and blood pressure control to reduce CV events
      • Strict glycemic control may not benefit patients with advanced CKD
      • Benefit of statins in moderate CKD not RRT
      • Some evidence shows CV risk reduction with aspirin in individuals with eGFR < 30 mL/min/1.73m²

    Stable Ischemic Heart Disease (SIHD)

    • SIHD is characterized by ischemia (reduced blood flow) but not infarction (heart tissue death)

    Symptoms of SIHD

    • Angina pectoris or stable angina
    • Neck or jaw pain
    • Shoulder or arm pain
    • Fast heartbeat
    • Shortness of breath (on exertion)
    • Nausea and vomiting
    • Sweating
    • Fatigue
    • Exclude: new chest pain, chest pain at rest, or positive biomarkers

    Risk Factors for SIHD

    • Atheroma in one or more coronary arteries
    • BMI > 27.5 kg/m²
    • Age and male sex
    • Diabetes mellitus
    • Smoking
    • Family history
    • Á LDL and/or â HDL
    • Hypertension
    • Alcohol abuse

    Risk Stratification

    • 2-3 modalities recommended for stratification

    Treatment Outcomes and Approach

    • Prevent acute coronary syndrome (MI) and death
    • Alleviate acute symptoms of myocardial ischemia
    • Prevent recurrent symptoms of myocardial ischemia
    • Prevent disease progression
    • Avoid or minimize adverse treatment effects

    Pharmacotherapy

    • Vasculoprotective therapy:
      • Behavioral modification therapy for all risks
      • Risk factor modification (ACEIs and statins)
      • Antiplatelet therapy
    • Anti-ischemic pharmacotherapy:
      • Beta blockers, nitrates, calcium-channel blockers, and trimetazidine
      • Others: ivabradine, nicorandil, ranolazine, SGLT2, and GLP-1RA

    Myocardial Revascularization

    • Must be done in high-risk patients

    Special Populations

    • Chronic kidney disease:
      • Limited data on efficacy and role of pharmacotherapy and revascularization
      • Importance of lifestyle modification, good glycemic and blood pressure control to reduce CV events
      • Strict glycemic control may not benefit patients with advanced CKD
      • Benefit of statins in moderate CKD not RRT
      • Some evidence shows CV risk reduction with aspirin in individuals with eGFR < 30 mL/min/1.73m²

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    Description

    This quiz assesses your understanding of stable ischemic heart disease, including treatment algorithms, interventions, and long-term treatment considerations.

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