Cardiovascular Outcomes in Obesity without Diabetes Study Insights
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Questions and Answers

What was the primary cardiovascular endpoint of the study?

  • Improvement in insulin sensitivity
  • Reduction in LDL cholesterol levels
  • Reduction in overall mortality rate
  • Time to first occurrence of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke (correct)

What was the mean weight loss observed in the semaglutide group?

  • 5.2%
  • 3.8%
  • 9.4% (correct)
  • 12.1%

What was the design of the trial?

  • Single-center, open-label, non-randomized
  • Multicenter, single-blind, non-randomized
  • Single-center, double-blind, randomized
  • Multicenter, double-blind, randomized, placebo-controlled (correct)

What did the study emphasize about the specific objectives?

<p>Focus on overweight and obese individuals without diabetes (A)</p> Signup and view all the answers

What did the study mention about the use of semaglutide?

<p>Reducing cardiovascular risk in patients with diabetes (A)</p> Signup and view all the answers

What was the duration of the multicenter, double-blind, randomized, placebo-controlled trial?

<p>12 months (C)</p> Signup and view all the answers

What were the specific secondary endpoints discussed in the study?

<p>Both b and c (D)</p> Signup and view all the answers

What was the mean weight loss observed in the placebo group?

<p>4.2% (C)</p> Signup and view all the answers

What was the focus of the study in terms of the participants' health status?

<p>Overweight and obese individuals with or without diabetes (B)</p> Signup and view all the answers

What did the study emphasize about the use of semaglutide in reducing cardiovascular risk?

<p>It significantly reduced cardiovascular death (A)</p> Signup and view all the answers

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