Cardiology Review: The Heart and Conduction System
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Questions and Answers

What is the primary mechanism of action of dihydropyridine calcium channel blockers?

  • Block sodium channels
  • Increase calcium influx
  • Enhance vascular tone
  • Inhibit calcium influx (correct)
  • Which of the following is a characteristic of non-dihydropyridine calcium channel blockers?

  • Marked negative inotropic effects (correct)
  • More potent vasodilators than DHPs
  • Reduced bradycardia
  • Faster onset of action
  • Which adverse effect is specifically associated with verapamil?

  • Fluid retention
  • Reflex tachycardia
  • Hypotension
  • Constipation (correct)
  • Which type of arrhythmia originates in the atria or AV nodal area?

    <p>Atrial fibrillation</p> Signup and view all the answers

    What is the heart rate classification for bradycardia?

    <p>&lt; 60 bpm</p> Signup and view all the answers

    Which class of antiarrhythmic drugs is known for possessing local anesthetic activity?

    <p>Class I</p> Signup and view all the answers

    Which calcium channel blocker is specifically associated with reflex tachycardia?

    <p>Nifedipine</p> Signup and view all the answers

    What is the main goal of antiarrhythmic drugs?

    <p>Restore normal cardiac rhythm</p> Signup and view all the answers

    Which of the following arrhythmias is considered the most serious?

    <p>Ventricular fibrillation</p> Signup and view all the answers

    Which of the following factors can lead to the development of arrhythmias?

    <p>Congestive heart failure</p> Signup and view all the answers

    What is the main purpose of the daily nitrate administration tip for patients on nitrate therapy?

    <p>To avoid potential tolerance during treatment</p> Signup and view all the answers

    Which of the following best describes the action of selective beta-blockers?

    <p>They primarily affect the heart while minimizing lung effects</p> Signup and view all the answers

    Which adverse effect is commonly associated with non-selective beta-blockers?

    <p>Hypotension</p> Signup and view all the answers

    What is a characteristic effect of dihydropyridine calcium channel blockers?

    <p>Predominantly peripheral vasodilatory actions</p> Signup and view all the answers

    What is the primary mechanism of action of Nitroglycerin?

    <p>Vasodilation through conversion to nitric oxide</p> Signup and view all the answers

    Which of the following is true about isosorbide dinitrate and isosorbide mononitrate?

    <p>Their mechanism of action is similar to nitroglycerin</p> Signup and view all the answers

    Which of the following is NOT a method of administration for Nitroglycerin?

    <p>Intramuscular injection</p> Signup and view all the answers

    When advising a patient about the use of beta-blockers, which of the following should be emphasized?

    <p>They are effective in managing chronic angina and hypertension</p> Signup and view all the answers

    What is the effect of Nitroglycerin on preload and afterload?

    <p>Decreases preload and decreases afterload</p> Signup and view all the answers

    What is a recommended practice regarding the handling of tablets containing medicinal substances?

    <p>They should not be shaken to prevent breaking</p> Signup and view all the answers

    Which beta-blocker is classified as selective?

    <p>Metoprolol</p> Signup and view all the answers

    Which of the following adverse effects is commonly associated with Nitroglycerin?

    <p>Headache</p> Signup and view all the answers

    What should patients do before using sublingual Nitroglycerin?

    <p>Sit down to avoid fainting</p> Signup and view all the answers

    How often can a patient repeat the use of Nitroglycerin sublingual tablets for acute angina if symptoms persist?

    <p>Every 5 minutes up to 3 times</p> Signup and view all the answers

    Which statement about Nitroglycerin is incorrect?

    <p>It has a long-lasting effect without side effects.</p> Signup and view all the answers

    Nitroglycerin is contraindicated if the patient has taken which type of medication?

    <p>Phosphodiesterase inhibitors</p> Signup and view all the answers

    What is a primary action of Class 2 antiarrhythmics?

    <p>Decrease excitability of cardiac cells</p> Signup and view all the answers

    What is a notable side effect of beta blockers?

    <p>Bradycardia</p> Signup and view all the answers

    What is the mechanism by which Amiodarone affects cardiac activity?

    <p>Interferes with potassium efflux</p> Signup and view all the answers

    Which of the following is a characteristic of Class 4 antiarrhythmics?

    <p>Decrease conduction velocity in nodes</p> Signup and view all the answers

    Which of the following best describes congestive heart failure (CHF)?

    <p>Condition where blood pools in the heart</p> Signup and view all the answers

    Which treatment option is NOT typically used for CHF?

    <p>Antidepressants</p> Signup and view all the answers

    What specific agent is used for ventricular arrhythmias when other drugs are ineffective?

    <p>Amiodarone</p> Signup and view all the answers

    What effect do calcium channel blockers typically have on the heart?

    <p>Decrease heart rate</p> Signup and view all the answers

    What is the primary purpose of diuretics in cardiac therapy?

    <p>Eliminate excess sodium and water from the urinary tract</p> Signup and view all the answers

    When is digoxin typically considered for treatment?

    <p>When diuretics and vasodilators are ineffective and myocardial contractility is weak</p> Signup and view all the answers

    What is a characteristic of cardiac glycosides like digoxin?

    <p>They increase the force of myocardial contractions without affecting oxygen consumption</p> Signup and view all the answers

    What does a narrow therapeutic index indicate in the context of cardiac glycosides?

    <p>Small changes in dosage can lead to toxicity or loss of effectiveness</p> Signup and view all the answers

    Which electrolyte imbalance can sensitize the heart to digoxin toxicity?

    <p>Hypokalemia</p> Signup and view all the answers

    What are common adverse effects of cardiac glycoside overdose?

    <p>Nausea, vomiting, and cardiac arrhythmias</p> Signup and view all the answers

    What effect does hypercalcemia have on the action of cardiac glycosides?

    <p>Enhances the drug's action</p> Signup and view all the answers

    Which of the following can reduce digoxin absorption?

    <p>Antacids and laxatives</p> Signup and view all the answers

    What is the primary function of the heart?

    <p>To act as a pump to deliver blood to body tissues</p> Signup and view all the answers

    Which part of the heart conduction system initiates electrical impulses?

    <p>Sinoatrial node</p> Signup and view all the answers

    What effect does norepinephrine have on the heart?

    <p>Increases heart rate and force of contraction</p> Signup and view all the answers

    Which of these is a symptom of congestive heart failure (CHF)?

    <p>Peripheral edema</p> Signup and view all the answers

    What differentiates unstable angina from classic angina?

    <p>It indicates an imminent myocardial infarction</p> Signup and view all the answers

    Arteriosclerosis is primarily associated with which of the following conditions?

    <p>Aging and hardening of arteries</p> Signup and view all the answers

    Which statement about myocardial infarction (MI) is true?

    <p>They can lead to tissue necrosis due to ischemia</p> Signup and view all the answers

    What role do the coronary arteries play in heart function?

    <p>They supply blood to the myocardium</p> Signup and view all the answers

    How does the autonomic nervous system influence heart function?

    <p>It regulates both heart rate and force of contraction</p> Signup and view all the answers

    What is a common consequence of myocardial infarction?

    <p>Replacement of muscle tissue with scar tissue</p> Signup and view all the answers

    Which type of angina is characterized by chest pain during exertion due to fixed obstruction?

    <p>Classic angina</p> Signup and view all the answers

    The term ejection fraction is best defined as:

    <p>The percentage of blood pumped out of a filled ventricle</p> Signup and view all the answers

    What happens to blood flow during congestive heart failure?

    <p>Less blood is pumped out than what is returned to the heart</p> Signup and view all the answers

    Study Notes

    Cardiology Review: The Heart

    • The heart is a pump, primarily muscle, delivering blood to body tissues.
    • The heart's four chambers have muscular walls that generate the force for blood circulation.
    • Three components vital for a functional heart are muscle (myocardium), conduction system (impulses), and nerve supply.

    Conduction System

    • The electrical impulse normally begins in the SA node, travels through the AV node, and then is distributed via the bundle of His, bundle branches, and Purkinje fibers to the ventricles.
    • Specialized conduction fibers in the myocardium initiate and sustain heart contraction.
    • The heart's inherent electrical stimulation allows for its self-initiated contractions.
    • The coordinated contraction of heart chambers results from the precise order of electrical impulse transmission.
    • An ECG (electrocardiogram) visually represents the depolarization and repolarization phases of the electrical conduction.

    Nerve Supply

    • The heart muscle (myocardium) is controlled by the autonomic nervous system's sympathetic and parasympathetic branches.
    • Sympathetic (fight-or-flight) stimulation increases heart rate and contractile force (norepinephrine).
    • Parasympathetic (rest) stimulation decreases heart rate and contractile force (acetylcholine).
    • The nervous system regulates both the rate and force of heart contraction.

    Main Diseases of the Heart

    • Congestive/Chronic Heart Failure (CHF)
    • Coronary Artery Disease (CAD)
    • Arteriosclerosis
    • Atherosclerosis
    • Angina Pectoris
    • Myocardial Infarction (MI)

    Congestive Heart Failure (CHF)

    • The heart struggles to adequately pump blood, leading to fluid buildup (edema) in the body.
    • CHF symptoms include swelling in the lungs (pulmonary edema), lower extremities (peripheral edema), tiredness, shortness of breath (dyspnea).
    • Treatment may involve medications like vasodilators and beta-blockers, and diuretics to reduce fluid.

    Coronary Artery Disease (CAD)

    • Insufficient blood flow to the myocardium through coronary arteries.
    • It is often linked to arteriosclerosis (hardening of arteries) and atherosclerosis (plaque buildup).
    • CAD can lead to angina pectoris (chest pain) due to temporary insufficient oxygen supply to the muscles. Different types of angina have varying characteristics.
    • Myocardial infarction (MI) is a serious complication of CAD, involving the death of heart muscle tissue due to blockage of a coronary vessel.

    Myocardial Infarction (MI)

    • This is a critical event with symptoms of chest pain, which may involve the blockage of a coronary artery.
    • Damage to heart muscle results, which may subsequently lead to conditions like heart failure.

    Antianginal Drugs

    • Medications like nitroglycerin, beta-blockers, and calcium channel blockers are frequently treatments for chest pain associated with CAD.
    • Nitrates work by opening (dilating) blood vessels, reducing blood pressure, and relieving pain associated with insufficient oxygen to heart cells.
    • Beta-blockers reduce heart rate and contractility.
    • Calcium channel blockers reduce the heart's workload by dilating the coronary blood vessels.

    Arrhythmias

    • Arrhythmias represent irregular heartbeats that originate from an abnormal heart rhythm.
    • Arrhythmias may stem from issues such as damaged hearts (e.g., from a previous coronary event), or from drug actions or interactions.
    • Medications like beta-blockers, calcium channel blockers, or digoxin treat heart rhythm disorders.

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    Cardiology Review PDF

    Description

    This quiz explores the anatomy and physiology of the heart, focusing on its structure and function. It covers the heart's chambers, muscle components, conduction system, and nerve supply. Test your knowledge on how the heart pumps blood and the electrical impulses that regulate its activity.

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