L6 part 2 physiology
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Questions and Answers

What equation is used to calculate cardiac output?

  • CO = SV x HR (correct)
  • CO = HR + ESV
  • CO = SV / HR
  • CO = SV + HR
  • What is the normal value of ejection fraction?

  • Greater than 60% (correct)
  • Between 50% and 60%
  • Exactly 70%
  • Less than 50%
  • Which factor influences stroke volume directly?

  • Ejection fraction
  • Afterload (correct)
  • Heart rate
  • Cardiac reserve
  • If a ventricle has an end diastolic volume of 120 ml and an end systolic volume of 45 ml, what is the stroke volume?

    <p>75 ml</p> Signup and view all the answers

    What does the Frank-Starling principle state?

    <p>Increased preload leads to increased stroke volume</p> Signup and view all the answers

    What is cardiac reserve?

    <p>The difference between resting and maximal cardiac output</p> Signup and view all the answers

    Which of the following correctly defines preload?

    <p>The volume of blood available for pumping</p> Signup and view all the answers

    How is cardiac output expressed?

    <p>In liters per minute</p> Signup and view all the answers

    What is cardiac output?

    <p>The volume of blood pumped each minute.</p> Signup and view all the answers

    The equation for cardiac output is CO = SV x _____.

    <p>HR</p> Signup and view all the answers

    What is the normal value of cardiac output?

    <p>5 L/min</p> Signup and view all the answers

    What is ejection fraction?

    <p>The percentage of blood ejected from the ventricle during each heartbeat.</p> Signup and view all the answers

    What is the normal ejection fraction value?

    <p>60%</p> Signup and view all the answers

    What are the components that determine stroke volume?

    <p>Preload, afterload, and contractility.</p> Signup and view all the answers

    Define cardiac reserve.

    <p>The difference between resting and maximal cardiac output.</p> Signup and view all the answers

    Calculate cardiac output if HR is 75 beats/min and SV is 70 ml/beat.

    <p>5250 ml/min or 5.25 L/min.</p> Signup and view all the answers

    Study Notes

    Cardiac Output

    • Defined as the volume of blood pumped by the heart every minute.
    • Measured in Litres/minute ( L/min)
    • Calculated by multiplying Stroke Volume (SV) by Heart Rate (HR): CO = SV x HR
    • Normal cardiac output is approximately 5 L/min.

    Cardiac Indices and Values

    • Ejection Fraction (EF): Percentage of blood ejected from the ventricle during each contraction.
      • Measured using echocardiography.
      • Calculated using the formula: EF = (SV/EDV) * 100% (where SV is Stroke Volume, EDV is End-Diastolic Volume)
      • Normal EF is greater than 60%.
    • Stroke Volume (SV): Volume of blood ejected from the ventricle with each heartbeat.
      • Calculated by subtracting End-Systolic Volume (ESV) from End-Diastolic Volume (EDV): SV = EDV - ESV.
    • End-Diastolic Volume (EDV): Volume of blood in the ventricle at the end of diastole (relaxation).
    • End-Systolic Volume (ESV): Volume of blood remaining in the ventricle at the end of systole (contraction).

    Factors Affecting Stroke Volume

    • Preload: The degree of stretch of the ventricle muscle fibers before contraction.
    • Afterload: The resistance the ventricle must overcome to eject blood (arterial pressure).
    • Contractility: The intrinsic strength of the ventricle muscle.

    Frank-Starling Principle

    • The heart pumps more blood with a greater preload (increased EDV), as long as contractility is not depressed.
    • This mechanism regulates the heart to maintain a steady cardiac output.

    Cardiac Reserve

    • Represents the difference between resting cardiac output and maximum cardiac output.
    • Represents how much more the heart can pump when needed (e.g., during exercise).

    Cardiac Output

    • Cardiac output refers to the volume of blood pumped each minute and is expressed by the equation: CO = SV x HR.
    • Normal cardiac output is approximately 5 L/min.
    • SV represents stroke volume, which is the amount of blood pumped per beat, and HR is the heart rate, or the number of beats per minute.

    Ejection Fraction

    • Ejection fraction is a measure of the heart's pumping efficiency.
    • It is the percentage of blood ejected from the left ventricle with each contraction.
    • It is most commonly measured using echocardiography.
    • A normal ejection fraction is greater than 60%.

    Stroke Volume

    • Stroke volume is the amount of blood ejected from the heart with each beat.
    • It is determined by three factors: preload, afterload, and contractility.
    • Preload: The volume of blood in the ventricle at the end of diastole
    • Afterload: The pressure the heart must overcome to eject blood.
    • Contractility: The force of contraction of the heart muscle.
    • Formula: SV = EDV - ESV.
    • EDV: End-diastolic volume, the amount of blood in a ventricle at the end of diastole.
    • ESV: End-systolic volume, the amount of blood remaining in a ventricle after contraction.

    Cardiac Reserve

    • Cardiac reserve is the difference between resting heart output and the maximum achievable cardiac output.
    • This represents the ability of the heart to increase its output during exercise or stress.

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    Description

    Test your knowledge about cardiac output, stroke volume, and ejection fraction. This quiz covers the definitions, calculations, and normal values for various cardiac indices. It's a great resource for students studying cardiovascular physiology.

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