Cardiac Cycle Overview

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Questions and Answers

During which phase of the cardiac cycle does the left ventricular volume decrease from 135mL to 65mL?

  • Ventricular systole (correct)
  • Atrial systole
  • Isovolumic ventricular contraction
  • Ventricular diastole

Which of the following events occurs immediately after the aortic valve closes?

  • Isovolumic ventricular relaxation (correct)
  • Atrial systole
  • Mitral valve opens
  • Aortic valve opens

Which of the following heart sounds is associated with the closing of the semilunar valves?

  • S1
  • S4
  • S3
  • S2 (correct)

During which phase of the cardiac cycle does the mitral valve open?

<p>Isovolumic ventricular relaxation (D)</p> Signup and view all the answers

Which of the following represents the end-diastolic volume of the ventricle?

<p>135 mL (D)</p> Signup and view all the answers

What action is responsible for a small amount of additional blood entering the ventricles during the cardiac cycle?

<p>Atrial contraction (B)</p> Signup and view all the answers

Which statement accurately describes the relationship between pressure and blood flow during the cardiac cycle?

<p>Blood flows from high pressure to low pressure (C)</p> Signup and view all the answers

Which of the following is NOT a general principle of the cardiac cycle?

<p>The left ventricle pumps blood to the lungs (C)</p> Signup and view all the answers

During which phase of the cardiac cycle do the semilunar valves snap closed?

<p>Isovolumic ventricular relaxation (A)</p> Signup and view all the answers

What is the primary function of the SA node in the cardiac cycle?

<p>Initiating electrical signals (C)</p> Signup and view all the answers

Which of these describes an event that occurs during late diastole?

<p>The heart is at rest (C)</p> Signup and view all the answers

What happens during isovolumic ventricular relaxation?

<p>The ventricles relax, pressure falls, and semilunar valves close (A)</p> Signup and view all the answers

Why is the heart considered a biological pump?

<p>It's capable of generating pressure gradients to direct blood flow (B)</p> Signup and view all the answers

Which of the following describes the event represented by point 'B' in the graph?

<p>The aortic pressure is at its highest point during systole. (C)</p> Signup and view all the answers

What does the 'Dicrotic notch' in the Wiggers diagram indicate?

<p>The closure of the semilunar valves. (A)</p> Signup and view all the answers

Which event corresponds with the upward deflection marked 'E' in the graph?

<p>The start of ventricular systole. (C)</p> Signup and view all the answers

Which phase of the cardiac cycle corresponds to the period between points 'C' and 'D'?

<p>Isovolumic ventricular contraction. (B)</p> Signup and view all the answers

Which of the following is TRUE regarding the relationship between left ventricular pressure and left ventricular volume during the period represented by 'F' in the graph?

<p>Both pressure and volume are decreasing. (A)</p> Signup and view all the answers

The interval between the first heart sound (S1) and the second heart sound (S2) represents which phase of the cardiac cycle?

<p>Ventricular systole. (A)</p> Signup and view all the answers

During isovolumic ventricular relaxation, which of the following is TRUE?

<p>All four heart valves are closed. (C)</p> Signup and view all the answers

Which of the following contributes to the peak of the 'Aorta' pressure curve in the Wiggers diagram?

<p>The contraction of the ventricles. (A)</p> Signup and view all the answers

Which event of the cardiac cycle MOST closely corresponds to the 'P' wave in the ECG?

<p>Atrial systole. (C)</p> Signup and view all the answers

What does the area enclosed by the pressure volume (PV) loop represent?

<p>Work done by the heart (B)</p> Signup and view all the answers

What happens to the PV loop if the heart rate increases?

<p>The loop becomes wider (C)</p> Signup and view all the answers

What happens to the PV loop if the contractility of the heart increases?

<p>The loop becomes larger (D)</p> Signup and view all the answers

What does the point labeled "A" represent on the PV loop?

<p>The beginning of ventricular filling (A)</p> Signup and view all the answers

What is represented by the difference in volume between point B and point A?

<p>End-diastolic volume (EDV) (B)</p> Signup and view all the answers

What is the typical range for stroke volume in a healthy adult?

<p>50-100 mL (D)</p> Signup and view all the answers

If the end-diastolic volume (EDV) is 135 mL and the end-systolic volume (ESV) is 65 mL, what is the stroke volume?

<p>70 mL (B)</p> Signup and view all the answers

Which of the following factors can influence the shape of the PV loop?

<p>All of the above (D)</p> Signup and view all the answers

What does the portion of the PV loop between points B and C represent?

<p>Isovolumetric contraction (D)</p> Signup and view all the answers

Flashcards

SA Node

The natural pacemaker of the heart that initiates electrical signals.

Cardiac Cycle

The sequence of events in one heartbeat, including diastole and systole.

Diastole

The phase when ventricles are relaxed and fill with blood.

Systole

The phase when ventricles contract to pump blood out.

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Atrial Systole

A phase where atria contract to push blood into ventricles.

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Isovolumic Ventricular Relaxation

The period when ventricles relax but no blood enters or leaves.

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Pressure Gradients

Difference in blood pressure that drives blood flow.

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Mechanics of the Cardiac Cycle

The ordered events of contraction and relaxation governing blood flow.

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End-diastolic Volume

The volume of blood in the left ventricle at the end of diastole before contraction.

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First Heart Sound (S1)

The sound produced by the closure of the AV valves during ventricular contraction.

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Second Heart Sound (S2)

The sound created by the closure of the semilunar valves at the end of ventricular systole.

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Auscultation

The act of listening to heart sounds using a stethoscope to assess heart health.

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End-systolic Volume

The volume of blood remaining in the left ventricle after contraction.

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Pressure Volume Loop

A graphical representation of pressure and volume throughout the cardiac cycle.

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End-Diastolic Volume (EDV)

The total volume of blood in the ventricle before contraction at the end of diastole.

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End-Systolic Volume (ESV)

The volume of blood remaining in the ventricle after contraction at the end of systole.

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Isovolumetric Contraction

Phase where ventricular muscles contract without changing volume, building pressure.

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Blood Ejection Phase

Phase of cardiac cycle where blood is expelled from the ventricles into the arteries.

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Stroke Volume

The amount of blood pumped by the heart with each contraction.

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Isovolumetric Relaxation

Period when the heart relaxes but there's no change in volume as the valves are closed.

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Ventricular Filling

The process where ventricles fill with blood during diastole.

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Pressure Rise in Ventricles

Increase in pressure during isovolumetric contraction as the ventricles prepare to eject blood.

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Phase A in PV Loop

Represents the filling of the ventricle (EDV) in the pressure-volume loop.

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Phase D in PV Loop

Represents the blood ejection phase where the heart pumps blood out.

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Ventricular Pressure

The pressure generated by the ventricles during contraction and relaxation.

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Ventricular Volume

The amount of blood present in the ventricles at any given time.

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Pressure-Volume Relationships

Correlations between pressure and volume that illustrate heart mechanics.

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Cardiac Cycle Phases

The sequence of events involving filling and emptying of the heart.

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Isovolumic Ventricular Contraction

The phase of the cardiac cycle where ventricles contract without change in volume, closing AV valves without opening semilunar valves.

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Ventricular Ejection

The phase where ventricular pressure exceeds arterial pressure, opening semilunar valves to eject blood.

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Semilunar Valves

Valves located at the exit of each ventricle, prevent backflow into the heart after blood is ejected.

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Dicrotic Notch

A small dip in the aortic pressure curve following the closure of the semilunar valves.

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Ventricular Diastole

The phase when the ventricles relax and fill with blood from the atria.

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QRS Complex

The electrical impulse on an ECG that corresponds to ventricular depolarization and contraction.

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Left Ventricular Volume

The volume of blood present in the left ventricle at any given time during the cardiac cycle.

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Atrial Diastole

The phase when the atria are relaxed and filling with blood from the veins.

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S1 and S2 Heart Sounds

S1 indicates closure of AV valves at the beginning of ventricular systole, while S2 signals closure of semilunar valves at the beginning of diastole.

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Wiggers Diagram

A graphical representation of the cardiac cycle illustrating pressures and volumes in the heart.

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Early Ventricular Diastole

The initial phase of ventricular relaxation where the ventricles begin filling with blood.

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Study Notes

Cardiac Cycle Overview

  • The cardiac cycle describes the sequence of events during a heartbeat
  • It involves two main phases: diastole (ventricles relax) and systole (ventricles contract)
  • Electrical signals initiate contraction and blood movement
  • Electrical signals originate in the SA node, propagate through the heart, and can be regulated
  • Contractile cells convert electrical signals to generate force and pump blood
  • This process requires coordinated electrical and contractile mechanisms
  • Cardiac function can be assessed by monitoring electrical signals and sounds

Mechanical Events of the Cardiac Cycle

  • Late diastole: Both heart chambers relax, ventricles fill passively
  • Atrial systole: Atrial contraction forces additional blood into ventricles
  • Isovolumic ventricular contraction: First phase of ventricular contraction; AV valves close but semilunar valves are not yet open
  • Ventricular ejection: Ventricular pressure exceeds arterial pressure, semilunar valves open and blood is ejected
  • Isovolumic ventricular relaxation: As ventricles relax, pressure falls, blood flows back, and semilunar valves close
  • These events are cyclical, and there are specific pressure and volume changes associated with each phase.

Heart Sounds

  • First heart sound ("lub"): Vibrations following closure of AV valves
  • Second heart sound ("dup"): Vibrations created by closing of semilunar valves

Wiggers Diagram

  • The diagram visually illustrates the relationship between electrical activity and pressure/volume changes during the cardiac cycle
  • It shows how events like mitral valve closure, aortic valve opening, and end diastolic volume relate to different stages of the cycle

Pressure-Volume Loops

  • These loops graphically represent the relationship between left ventricular pressure and volume during the cardiac cycle
  • Different phases of the cycle (e.g., isovolumetric contraction, ejection, isovolumetric relaxation) are shown as distinct parts of the loop
  • Critical values include:
    • End-diastolic volume (EDV)
    • End-systolic volume (ESV)
    • Stroke volume
  • These loops display how atrial filling pressure and aortic pressure affect the filling and ejection cycle.

Further Applications of Cardiac Cycle Knowledge

  • Understanding normal valve function is important
  • Irregularities in the valve operation, such as leakage, can be diagnosed using this knowledge
  • Techniques for diagnosing these irregularities are important clinical applications of the cardiac cycle mechanisms.

Key Terms

  • Diastole: Relaxation phase of the ventricles
  • Systole: Contraction phase of the ventricles
  • SA node: Sinoatrial node, the heart's pacemaker
  • AV valves: Atrioventricular valves (tricuspid and mitral)
  • Semilunar valves: Pulmonary and aortic valves
  • EDV: End-diastolic volume
  • ESV: End-systolic volume
  • Stroke volume: Volume of blood ejected per beat

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