Cardiac Function Curve Quiz: Master Cardiac and Vascular Function Curves

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Questions and Answers

What is the pressure in the right atrium typically fluctuating around?

10 mmHg

15 mmHg

2 mmHg

5 mmHg (correct)

How does an increase in Right Atrial Pressure (RAP) affect venous return?

Increases venous return

Decreases venous return (correct)

Disrupts the steady state relationship with cardiac output

Has no effect on venous return

What determines venous return at steady state?

Mean circulatory pressure (MCP)

Right atrial pressure (RAP)

Cardiac output (CO) (correct)

Central venous pressure (CVP)

What does the vascular function curve show the relationship between?

Venous return and cardiac output Signup and view all the answers

Which of the following shifts the match between cardiac output and venous return?

Increase in contractility Signup and view all the answers

What does the mean systemic filling pressure (MSFP) represent?

The theoretical pressure if the heart pump is turned off Signup and view all the answers

What is the theoretical pressure that would exist if the heart pump is turned off and blood is allowed to distribute throughout the vasculature until pressure is equal throughout?

Mean circulatory pressure (MCP) Signup and view all the answers

Which part of the cardiovascular system receives 64% of total blood volume in the systemic circulation?

Systemic Venous system Signup and view all the answers

How do changes in blood volume and venous compliance affect the cardiac function curve?

Cause parallel shifts without changing Mean circulatory pressure (MCP) Signup and view all the answers

What does altering systemic vascular resistance (SVR) affect in the systemic function curves?

Alters the slope without changing Mean circulatory filling pressure (Pmc) Signup and view all the answers

Which part of the cardiovascular system receives 7% of total blood volume in the systemic circulation?

Capillaries Signup and view all the answers

What is the structure responsible for receiving blood from the veins and pumping it to the right ventricle of the heart?

Right Atrium Signup and view all the answers

What is the main physiological effect of Natriuretic Peptides on blood vessels?

Promote smooth muscle cell relaxation Signup and view all the answers

Which of the following is NOT a role of Natriuretic Peptides?

Promote vasoconstriction Signup and view all the answers

What is the main downstream effect of Natriuretic Peptides?

Promote smooth muscle cell relaxation Signup and view all the answers

Which receptor type is primarily responsible for the main physiological effect of Natriuretic Peptides on blood vessels?

Receptor type A Signup and view all the answers

What are the main diagnostic markers associated with Natriuretic Peptides?

Troponin and Brain Natriuretic Peptide (BNP) Signup and view all the answers

Which hormone is predominantly involved in promoting diuresis and natriuresis?

ANP (Atrial Natriuretic Peptide) Signup and view all the answers

Study Notes

Venous Return and Cardiac Output

Venous return (VR) determines right atrial pressure (RAP)
RAP determines VR
At steady state, VR = cardiac output (CO)

Mean Systemic Filling Pressure (MSFP)

Theoretical pressure if heart pump is turned off and blood is distributed throughout vasculature
Changes with changes in venous compliance or capacitance, and blood volume

Right Atrial Pressure (RAP)

Typically low, fluctuating around a mean of 0 mmHg
Required for pressure gradient to drive venous return (VR)
Difference between central venous pressure (CVP) and RAP is the driving pressure for blood into the atrium (ΔP = CVP-RAP)

Vascular Function Curve

Shows the relationship between venous return and right atrial pressure
Changes in blood volume and venous compliance cause parallel shifts in the curve
Changes in systemic vascular resistance (SVR) alter the slope of the curve without changing MSFP