Carbohydrates Overview and Classification

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Questions and Answers

What condition occurs when blood glucose concentration falls below 3 mM for an extended period?

  • Stomach cramps
  • Increased energy levels
  • Diabetes
  • Confusion and coma (correct)

Which type of glycosidic bond does α-amilase disrupt?

  • α(1->4) bonds (correct)
  • α(1->6) bonds
  • Mixed glycosidic bonds
  • β(1->4) bonds

Which transporter is responsible for the absorption of glucose and galactose in the intestine?

  • SGLT-2
  • SGLT-1 (correct)
  • GLUT-2
  • GLUT-5

What is the typical blood glucose concentration maintained at about 5 mM?

<p>90 mg/dL (C)</p> Signup and view all the answers

Which substance cannot be digested by humans due to beta bonds?

<p>Cellulose (A)</p> Signup and view all the answers

What is the general formula for carbohydrates?

<p>(C.H2O)n (B)</p> Signup and view all the answers

Which of the following describes a disaccharide?

<p>It is formed by two monosaccharides linked by a glycosidic bond. (D)</p> Signup and view all the answers

Which term is used to classify carbohydrates containing three or more sugar units?

<p>Polysaccharide (C)</p> Signup and view all the answers

Fructose and glucose are examples of which type of carbohydrates?

<p>Monosaccharides (A)</p> Signup and view all the answers

What distinguishes aldose sugars from ketose sugars?

<p>The type of carbonyl group: aldehyde vs ketone (A)</p> Signup and view all the answers

Which polysaccharide is primarily responsible for energy storage in animals?

<p>Glycogen (D)</p> Signup and view all the answers

Which of the following carbohydrates is considered a storage polysaccharide?

<p>Glycogen (D)</p> Signup and view all the answers

What is a characteristic feature of polysaccharides like cellulose and chitin?

<p>They provide structural support. (D)</p> Signup and view all the answers

What type of bond forms between two monosaccharides to create a disaccharide?

<p>Glycosidic bond (A)</p> Signup and view all the answers

If a carbohydrate is classified as an aldopentose, how many carbons does it contain?

<p>5 (C)</p> Signup and view all the answers

What is the primary structural feature of proteoglycans?

<p>Negatively charged heteropolysaccharide chains associated with a core protein (D)</p> Signup and view all the answers

Which statement accurately describes glycoproteins?

<p>They are proteins with covalently attached oligosaccharides. (D)</p> Signup and view all the answers

What is one of the common functions of glycoproteins in the human body?

<p>Cell-surface recognition and antigenicity (C)</p> Signup and view all the answers

How do glycosaminoglycans contribute to the extracellular matrix?

<p>By binding large amounts of water to create a gel-like matrix (D)</p> Signup and view all the answers

What distinguishes amylose from amylopectin?

<p>Amylose is a linear chain of glucose, whereas amylopectin has branches. (A)</p> Signup and view all the answers

What effect does an increased number of branches have on carbohydrate degradation?

<p>It allows for faster energy production. (C)</p> Signup and view all the answers

Which component is NOT part of the extracellular matrix?

<p>Glycogen (B)</p> Signup and view all the answers

What determines the blood group type in relation to glycoproteins?

<p>The terminal sugar on the glycan chain (C)</p> Signup and view all the answers

Flashcards

What are Carbohydrates?

A group of carbonyl compounds (aldehydes or ketones) that also contain several hydroxyl groups.

What is the general formula for carbohydrates?

The general formula for carbohydrates is (C.H2O)n, where 'n' represents the number of carbon atoms in the molecule.

What are isomers in the context of carbohydrates?

Isomers have the same chemical formula but different structural arrangements. For example, fructose and glucose both have the formula C6H12O6, but their atoms are arranged differently.

What are monosaccharides?

Monosaccharides are the simplest form of carbohydrates and cannot be broken down further. They typically consist of 3-7 carbon atoms.

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What are disaccharides?

Disaccharides are formed when two monosaccharides join together through a glycosidic bond.

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What are polysaccharides?

Polysaccharides are complex carbohydrates that consist of many monosaccharide units linked together. Examples include starch, glycogen, and cellulose.

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What is glycogen?

Glycogen is a branched polysaccharide that serves as the main storage form of glucose in animals. It is found primarily in the liver and muscles.

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What is starch?

Starch is a polysaccharide that is a major storage form of glucose in plants. It is made up of two types of molecules: amylose and amylopectin.

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What is cellulose?

Cellulose is a structural polysaccharide that forms the cell walls of plants. It is the most abundant organic compound on Earth.

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What is chitin?

Chitin is a structural polysaccharide that is found in the exoskeletons of insects and crustaceans and the cell walls of fungi.

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What is a glycosidic bond?

A type of bond that links monosaccharides together to form disaccharides and polysaccharides.

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What is an α-amylase?

A type of enzyme found in the mouth and intestines that breaks down starch, a type of glucose polymer.

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What is SGLT-1?

A type of transporter protein in intestinal mucosal cells that helps absorb glucose and galactose from the gut into the bloodstream.

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What is GLUT-5?

A transporter protein in intestinal mucosal cells that helps absorb fructose from the gut into the bloodstream.

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What is GLUT-2?

A type of transporter protein in the intestinal cells that helps move glucose from the intestines to the bloodstream.

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Amylopectin

A type of polysaccharide composed of glucose units joined by glycosidic bonds, with branched structures, making it suitable for rapid energy production.

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Amylose

A type of polysaccharide composed of linear chains of glucose units joined by glycosidic bonds.

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Proteoglycan

A large molecule consisting of a core protein to which long chains of negatively charged glycosaminoglycans (GAGs) are attached.

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Glycosaminoglycans (GAGs)

Long, unbranched polysaccharide chains composed of repeating disaccharide units, found in connective tissues and providing structural support.

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Glycoprotein

Proteins to which oligosaccharides (glycans) are covalently attached, playing a role in cell recognition, cell signaling, and various other functions.

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Glycosylation

The process of adding sugar molecules (glycans) to proteins, modifying their functions and structures.

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Mucous secretions

A substance found in the extracellular matrix (ECM) and various body fluids, providing lubrication and contributing to the gel-like nature of tissues.

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Extracellular Matrix (ECM)

A complex network of macromolecules that provides structural support, cell adhesion, and signaling functions in tissues.

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Study Notes

Carbohydrates Overview

  • Carbohydrates are carbonyl compounds (aldehydes or ketones)
  • They also contain several hydroxyl groups
  • Carbohydrates are classified based on the number of sugar units
  • The general formula for carbohydrates is (CH2O)n
  • Isomers have the same chemical formula but different structures

Objectives

  • Recognize the general structure of carbohydrates
  • Classify carbohydrates (monosaccharides, disaccharides, oligosaccharides, polysaccharides)
  • Recognize disaccharides
  • Recognize polysaccharides
  • Explain carbohydrate-modified protein structures and their functions
  • Explain carbohydrate digestion

Carbohydrate Classification

  • Monosaccharides: single sugar units
    • Aldoses: have an aldehyde group
    • Ketoses: have a ketone group
    • Examples: glucose, fructose, galactose, ribose
  • Disaccharides: two monosaccharides linked together
    • Examples: sucrose, lactose, maltose
  • Polysaccharides: numerous monosaccharides linked together
    • Examples: starch, glycogen, cellulose, chitin
  • Classification by the number of units:
    • Mono, di, oligo, poly

Monosaccharides

  • Aldoses have an aldehyde group on carbon 1
  • Ketoses have a ketone group on carbon 2
  • Classified further by the number of carbon atoms (e.g., trioses, tetroses, pentoses, hexoses)
  • Important examples: glucose, fructose, galactose, ribose, deoxyribose, fucose

Disaccharides

  • Formed by linking two monosaccharides through a glycosidic bond
  • The glycosidic bond involves the dehydration reaction
  • Examples: maltose, sucrose, lactose

Polysaccharides

  • Formed by linking numerous monosaccharides together
  • Examples: glycogen, starch, cellulose, chitin
  • Starch and glycogen are storage polysaccharides
  • Cellulose and chitin are structural polysaccharides

Protein-Carbohydrate Structures

  • Carbohydrates can combine with proteins
  • If the carbohydrate is more abundant, it can further modify the properties of the proteins
  • Glycoproteins and proteoglycans are examples of proteins linked to carbohydrates

Digestion

  • Carbohydrates are broken down to monosaccharides during digestion
  • Enzymes such as amylase break down polysaccharides into simpler forms in the mouth & intestine
  • Carbohydrates with α-glycosidic bonds are digested easily, such as starch
  • Carbohydrates with β-glycosidic bonds are not easily digested in humans, like cellulose

Absorption

  • Monosaccharides are absorbed into the bloodstream after digestion
  • Glucose, galactose are absorbed using a sodium-dependent transporter (SGLT1)
  • Fructose is absorbed using a different transporter (GLUT5)

Carbohydrate Metabolism

  • Blood glucose levels are tightly regulated
  • Normal blood glucose levels are crucial for brain function
  • High or low blood glucose levels for long periods can lead to health problems

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