Carbapenems Quiz

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Questions and Answers

Which carbapenem is usually coadministered with cilastatin to inhibit its degradation in the kidneys?

Imipenem (correct)
Ertapenem
Meropenem
None of the above

Which carbapenem is highly resistant to β-lactamases and is active against Pseudomonas aeruginosa and Enterococcus?

Ertapenem
Imipenem
Meropenem (correct)
None of the above

Which carbapenem does not need to be coadministered with cilastatin to inhibit its degradation in the kidneys?

Ertapenem
Imipenem
Meropenem (correct)
None of the above

What is the mechanism of action of the cyclic polypeptides produced by Bacillus bacteria?

Inhibiting cell wall synthesis by interfering with the molecules that carry peptidoglycan subunits across the cell membrane to their site in the cell wall (A) Signup and view all the answers

Why are the cyclic polypeptides usually used topically?

Due to their high toxicity (nephrotoxic) (C) Signup and view all the answers

Against which type of bacteria are the cyclic polypeptides highly effective?

Gram-positive bacteria (B) Signup and view all the answers

Which of the following best describes the bactericidal activity of the cyclic polypeptides produced by Bacillus bacteria?

Inhibiting cell wall synthesis by interfering with the molecules that carry peptidoglycan subunits across the cell membrane (C) Signup and view all the answers