9 Questions
Which carbapenem is usually coadministered with cilastatin to inhibit its degradation in the kidneys?
Imipenem
Which carbapenem is highly resistant to β-lactamases and is active against Pseudomonas aeruginosa and Enterococcus?
Meropenem
Which carbapenem does not need to be coadministered with cilastatin to inhibit its degradation in the kidneys?
Meropenem
What is the mechanism of action of the cyclic polypeptides produced by Bacillus bacteria?
Inhibiting cell wall synthesis by interfering with the molecules that carry peptidoglycan subunits across the cell membrane to their site in the cell wall
Why are the cyclic polypeptides usually used topically?
Due to their high toxicity (nephrotoxic)
Against which type of bacteria are the cyclic polypeptides highly effective?
Gram-positive bacteria
Which of the following best describes the bactericidal activity of the cyclic polypeptides produced by Bacillus bacteria?
Inhibiting cell wall synthesis by interfering with the molecules that carry peptidoglycan subunits across the cell membrane
Why are the cyclic polypeptides usually used topically?
Due to their high nephrotoxicity
Against which type of bacteria are the cyclic polypeptides highly effective?
Gram-positive bacteria
Test your knowledge of carbapenems, a group of β-lactam antibiotics highly resistant to β-lactamases. This quiz covers drugs like ertapenem, imipenem, and meropenem, their mechanisms of action, and spectrum of activity against Gram-positive and Gram-negative bacteria including Pseudomonas aeruginosa and Enterococcus.
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