Questions and Answers
What is the common name for Captopril?
What drug class does Captopril belong to?
Angiotensin-Converting Enzyme (ACE Inhibitor)
List three pharmacotherapeutic uses of Captopril.
Hypertension, Congestive heart failure, Diabetic nephropathy
How does Captopril work pharmacodynamically?
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Which of the following is a contraindication for administering Captopril?
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Which of the following is an adverse effect of Captopril?
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What should be assessed before administering Captopril?
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What is the recommended administration guideline for Captopril regarding meals?
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Study Notes
Captopril Overview
- Commonly known as Capoten.
- Belongs to the class of Angiotensin-Converting Enzyme (ACE) inhibitors.
Pharmacotherapeutics
- Indicated for the treatment of hypertension (HTN).
- Effective in managing congestive heart failure.
- Used in diabetic nephropathy to protect kidney function.
- Aids in left ventricular dysfunction.
Pharmacodynamics
- Inhibits ACE, blocking the conversion of inactive angiotensin I to active angiotensin II.
- Reduction in angiotensin II leads to decreased aldosterone secretion, preventing sodium and water retention.
- Less angiotensin II results in reduced vasoconstriction, promoting vasodilation.
Contraindications
- Contraindicated during the 2nd and 3rd trimesters of pregnancy due to potential fetal harm (BLACK BOX warning).
- Should not be administered to individuals with hypersensitivity.
- Caution against use in patients already taking other ACE inhibitors due to possible cross-sensitivity.
Adverse Effects
- Common side effects include persistent nonproductive cough and rash.
- May cause hypotension, hyperkalemia (elevated potassium levels), and hyponatremia (excessive sodium levels).
Patient Education
- Measure blood pressure prior to administering the drug.
- Anticipate a smaller antihypertensive effect in African American patients compared to Caucasian patients.
- Administer captopril at least one hour before meals as food can inhibit absorption.
- Monitor patients for at least two hours post-initial dose until blood pressure stabilizes.
- Regularly assess laboratory values for hyperkalemia, hypernatremia, neutropenia, and proteinuria.
- Continuously monitor blood pressure throughout the duration of therapy.
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Description
Test your knowledge of Captopril, commonly known as Capoten, an ACE inhibitor used for various pharmacotherapeutic purposes. This quiz covers its definitions, classifications, pharmacodynamics, and therapeutic uses. Perfect for medical students or anyone interested in pharmacology.
