18 Questions
What is the purpose of the coating modification in soft gelatin capsules?
To decrease the solubility of the capsule
Which of the following is not a method of manufacturing soft gelatin capsules?
Spray Drying Process
What is the cause of 'Blooming' in soft gelatin capsules?
High concentration and low molecular weight of plasticizer
What is the cause of 'Twinning' in tablets?
Inappropriate tablet shape or tracky coating formulation
What is the cause of 'Orange Peel' defect in tablet coatings?
Inadequate spreading of the coating
What is the purpose of the 'Thermal Coupling' method in sealing gelatin capsules?
To use a liquid wetting agent to lower the melting point between cap and body, then bond them
Which of the following is a problem associated with the flowability of materials in tablet manufacturing?
Arching/Bridging
What is the typical moisture content range for the wet granulation process in tablet manufacturing?
31-35%
Which of the following is an advantage of fluid bed granulation over traditional granulation methods?
Easier and faster process
Which of the following is a requirement for direct compression tablet processing without granulation?
Good flowability and compressibility
Which of the following is a type of dry granulation method mentioned in the text?
Double compression
What is the purpose of coating tablets in the manufacturing process?
To prevent capping and lamination
What is the main disadvantage of the oldest method of sugar coating tablets?
All of the above
What is the purpose of the sealing step in the sugar coating process?
To waterproof the tablet core and separate it from water
Which of the following is NOT a common sub-coating agent used in the sugar coating process?
Talc
Which step in the sugar coating process is considered the most critical?
Sub-coating
Which type of tablet defect is caused by air entrapment during the tableting process?
Capping and lamination
Which type of tablet defect is caused by excessive moisture in the tablet formulation?
Sticking and picking
Test your knowledge on capsule encapsulation methods such as Sealing Gelatin Banding, Heat Welding, and Thermal Coupling. Learn about coating techniques that modify solubility characteristics. Explore the process of forming, filling, and sealing Soft Gelatin Capsules (SGC).
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
