Capillary Fluid Exchange and Lymphatic System

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21 Questions

What is the process by which substances move across the capillary membrane from an area of high concentration to an area of low concentration?

Diffusion

Which process involves the transport of large molecules across the capillary wall inside vesicles?

Transcytosis

What is responsible for the outward force that tends to move fluid from the capillaries into the interstitial fluid?

Hydrostatic pressure inside the capillary

What is the inward force that tends to move fluid from the interstitial fluid into the capillaries?

Osmotic pressure in the interstitial fluid

What is the formula for calculating net filtration pressure (NFP)?

$NFP = (HPc + OPif) - (HPif + OPc)$

What term describes an abnormal accumulation of fluid in the interstitial spaces of tissues?

Edema

What specifically prevents substances such as bacteria or large proteins from entering the lymphatic vessels?

Small openings between lymphatic endothelial cells

Where are discontinuous capillaries most commonly found?

Liver

What is the main function of fenestrated capillaries?

Allowing high volumes of fluid to pass rapidly between plasma and interstitial fluid

What is the relative permeability of skeletal muscle capillary pores to glucose molecules compared to water molecules?

0.6 times

What is the role of transcytosis vesicles in capillary endothelial cells?

Transporting macromolecules across the cell membrane

Where are 'tight' junctions between capillary endothelial cells mainly found?

Brain

Which body fluid compartment primarily consists of fluid surrounding most cells of the body?

Interstitial fluid

What is the structure entrapping interstitial fluid among proteoglycan filaments called?

Tissue gel

What is the relative permeability of capillary pores to albumin molecules compared to water molecules?

< 1/1000 times

Which type of capillaries have large gaps and fenestrae?

'Sinusoidal' capillaries

What is the main function of transcytosis vesicles in capillary endothelial cells?

Facilitating the movement of large molecules across the capillary wall inside vesicles

What specifically prevents substances such as bacteria or large proteins from entering the lymphatic vessels?

The tight junctions between capillary endothelial cells in the brain

What is the relative permeability of skeletal muscle capillary pores to glucose molecules compared to water molecules?

0.6 times

Where are 'tight' junctions between capillary endothelial cells mainly found?

Brain

What is responsible for the outward force that tends to move fluid from the capillaries into the interstitial fluid?

Partial pressure gradient for the individual gas

Test your understanding of capillary exchange, factors affecting it, hydrostatic and osmotic pressures, calculation of net filtration pressure, edema, and alterations in capillary exchange. Explore concepts like diffusion, transcytosis, and bulk flow.

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