Cancer Immunotherapy
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Questions and Answers

Which cells can be replenished after antibody treatment is stopped?

  • Tumor specific T cells
  • Normal B cells (correct)
  • Cancer cells
  • Hematopoietic stem cells
  • Which antibodies are used in cancer therapy to block growth factor signaling?

  • Anti-Her2/Neu
  • Anti-EGF-receptor (correct)
  • Anti-vascular endothelial growth factor
  • Anti-CD20
  • What is the process of adoptive T cell therapy with CAR-T cells?

  • Expansion of T cells with anti-CD3 and anti-CD28
  • Genetic modification of T cells to express recombinant chimeric antigen receptors (CARs)
  • Transfer of T cells back into the patient
  • All of the above (correct)
  • Which of the following is a main strategy for cancer immunotherapy mentioned in the text?

    <p>Introduction of antitumor antibodies</p> Signup and view all the answers

    What is the purpose of using monoclonal antibodies in tumor immunotherapy?

    <p>To activate tumor-specific immunity</p> Signup and view all the answers

    What has largely supplanted the initial empirical approaches in cancer immunotherapy?

    <p>Rational strategies based on improved understanding of immune responses</p> Signup and view all the answers

    Study Notes

    Cancer Immunotherapy

    • Immune cells that can be replenished after antibody treatment is stopped are memory T cells.

    Antibody Treatment in Cancer Therapy

    • Monoclonal antibodies are used in cancer therapy to block growth factor signaling, targeting specific molecules that promote cancer growth.

    CAR-T Cell Therapy

    • Adoptive T cell therapy with CAR-T cells involves collecting T cells from a patient, genetically modifying them to produce chimeric antigen receptors (CARs), expanding the modified cells, and reinfusing them into the patient to target cancer cells.

    Strategies for Cancer Immunotherapy

    • A main strategy for cancer immunotherapy is targeted therapy, which involves using antibodies or small molecules to block specific molecules that promote cancer growth.

    Monoclonal Antibodies in Tumor Immunotherapy

    • The purpose of using monoclonal antibodies in tumor immunotherapy is to selectively target and destroy cancer cells while sparing normal cells.

    Advances in Cancer Immunotherapy

    • Rational design approaches have largely supplanted the initial empirical approaches in cancer immunotherapy, allowing for more precise and effective treatment strategies.

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    Description

    Test your knowledge on the latest strategies in cancer immunotherapy! Explore topics such as antitumor antibodies, autologous T cells, immune checkpoint inhibitors, and vaccination. Discover the advancements in treating disseminated cancers that cannot be cured surgically.

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