Cancer Immunotherapy

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Questions and Answers

Which cells can be replenished after antibody treatment is stopped?

Normal B cells

Which antibodies are used in cancer therapy to block growth factor signaling?

Anti-EGF-receptor

What is the process of adoptive T cell therapy with CAR-T cells?

All of the above

Which of the following is a main strategy for cancer immunotherapy mentioned in the text?

<p>Introduction of antitumor antibodies</p> Signup and view all the answers

What is the purpose of using monoclonal antibodies in tumor immunotherapy?

<p>To activate tumor-specific immunity</p> Signup and view all the answers

What has largely supplanted the initial empirical approaches in cancer immunotherapy?

<p>Rational strategies based on improved understanding of immune responses</p> Signup and view all the answers

Study Notes

Cancer Immunotherapy

  • Immune cells that can be replenished after antibody treatment is stopped are memory T cells.

Antibody Treatment in Cancer Therapy

  • Monoclonal antibodies are used in cancer therapy to block growth factor signaling, targeting specific molecules that promote cancer growth.

CAR-T Cell Therapy

  • Adoptive T cell therapy with CAR-T cells involves collecting T cells from a patient, genetically modifying them to produce chimeric antigen receptors (CARs), expanding the modified cells, and reinfusing them into the patient to target cancer cells.

Strategies for Cancer Immunotherapy

  • A main strategy for cancer immunotherapy is targeted therapy, which involves using antibodies or small molecules to block specific molecules that promote cancer growth.

Monoclonal Antibodies in Tumor Immunotherapy

  • The purpose of using monoclonal antibodies in tumor immunotherapy is to selectively target and destroy cancer cells while sparing normal cells.

Advances in Cancer Immunotherapy

  • Rational design approaches have largely supplanted the initial empirical approaches in cancer immunotherapy, allowing for more precise and effective treatment strategies.

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