54 Questions
What is the primary aim of tertiary cancer prevention according to the text?
Reducing symptoms and morbidity of cancer
What is the primary cause of Chemotherapy-Induced Neuropathy?
Axonal transport interference
Which platinum-based chemotherapy agent is noted as the most detrimental in causing acute Oxaliplatin-Induced Peripheral Neuropathy?
Oxaliplatin
What symptom is common in patients experiencing acute Oxaliplatin-Induced Peripheral Neuropathy?
Muscle cramps
Which statement regarding Chemotherapy-Induced Neurotoxicity is true?
It primarily affects the central nervous system
What percentage of patients may experience cold-induced hypersensitivity as a symptom of Acute Oxaliplatin-Induced Peripheral Neuropathy?
71%
What are some potential consequences of Acute Oxaliplatin-Induced Peripheral Neuropathy?
Chemo dose reduction
What is one of the 'CAUTIONS' listed as a warning sign of cancer?
Long-term constipation
Which of the following is a 'CAUTION' associated with cancer diagnosis according to the text?
Persistent back pain
What warning sign of cancer involves a sore that does not heal in 6 weeks?
Unusual bleeding or discharge
Which of the following could be indicative of cancer according to the text?
Obvious change in wart or mole
What might be a warning sign of cancer based on experiencing thickening or a lump in certain areas?
Thickening or lump in breast or elsewhere
'Nagging cough or hoarseness' is mentioned as a warning sign of cancer. Which option best describes these symptoms?
Persistent, long-term coughing or throat irritation
What is the major long term effect of endocrine therapy?
Peripheral neuropathy
Which side effect is NOT associated with therapeutic radiation?
Mood swings & fatigue
How does radiation therapy destroy cancer cells?
Destroys hydrogen bonds between DNA strands in cancer cells
Which type of radiation therapy sculpts the beam and minimizes damage to healthy tissue?
Proton beam therapy
What is a common side effect of bone density loss?
Joint pain/arthralgias
What is the main pathophysiological process involved in radiation-induced tissue fibrosis?
Release of cytokines & growth factors
Which cells are primarily responsible for the increased synthesis of the Extracellular Matrix (ECM) in fibrosis?
Fibroblasts
What is a common consequence of radiation therapy in addition to tissue fibrosis?
Alopecia
Which of the following is NOT a potential cause of fibrosis according to the text?
Diabetes
In stem cell transplantation, what types of malignancies can be treated using this procedure?
Multiple myeloma and Leukemias
Which group of cells play a key role in the development of fibrosis through recruitment and proliferation in response to tissue injury?
Macrophages
What is a less common side effect of endocrine therapy for breast cancer mentioned in the text?
Muscle weakness
In addition to muscle weakness and osteoporosis, what other less common side effect is associated with endocrine therapy?
Blood clots
Which condition is noted as a potential consequence of endocrine therapy in men with prostate cancer?
Headaches
What is a side effect that may occur in men undergoing endocrine therapy for prostate cancer, according to the text?
Skin rash
Besides headaches, which symptom is noted in men undergoing endocrine therapy for prostate cancer?
Bone pain
Which side effect is specifically mentioned as common in men undergoing endocrine therapy for prostate cancer?
Fatigue
What type of biopsy involves removing the entire area along with a healthy margin for examination?
Surgical biopsy
Which imaging technique uses a wire with a hook at the end to mark the abnormal area for biopsy?
Ultrasound-guided biopsy
What is the primary purpose of tumor markers in cancer diagnosis and treatment?
Assessing responsiveness to various medical treatments
Which substance is NOT typically analyzed as a tumor marker?
Antibiotics
In cancer diagnosis, what is the purpose of a PET-CT scan?
Assessing cellular metabolism in tissues
Which procedure involves using a wide needle sample to obtain tissue from a suspicious area?
Core needle sample
What is the most common example of neuropathy induced by Oxaliplatin according to the text?
Tinnitus
How long does it typically take for most individuals who have experienced 'Chemo brain' to return to full cognitive function?
1-2 months
Which of the following is a common symptom associated with Vincristine-induced neurotoxicity?
Constipation
What percentage of adult cancer survivors may experience Ototoxicity?
40%-50%
In the context of chemotherapy, what does 'Coasting' refer to?
The progression of symptoms from acute to chronic
Which chemotherapy agent is specifically mentioned as causing paralytic ileus when combined with itraconazole?
Vincristine
What is a potential side effect of therapeutic radiation therapy that involves the destruction of hydrogen bonds between DNA strands in cancer cells?
Liver damage
Which long-term side effect of endocrine therapy is characterized by chemotherapy-induced peripheral neuropathy?
Bone loss
What is a possible consequence of total body irradiation (TBI) used before stem cell transplant?
Hair loss
Which side effect is associated with intensity-modulated radiation therapy (IMRT) in cancer treatment?
Cardiotoxicity
What is a potential side effect of therapeutic radiation involving skin color changes, desquamation, and swelling?
Fatigue
Which common long-term effect of endocrine therapy may manifest as cancer-related fatigue?
Gynecomastia
What is the primary role of fibroblasts in the development of fibrosis?
Increased synthesis of ECM
Which of the following factors is not mentioned as a cause of tissue injury leading to fibrosis?
Diabetes
What is a notable cellular response to tissue injury that contributes to fibrosis?
Activation of platelets
Which type of stem cell transplantation is mentioned in the text as being used for treating solid tumors?
Autologous stem cell transplantation
What are the primary cells responsible for recruitment and proliferation in response to tissue injury?
Macrophages
Which term is used to describe the increased synthesis and degradation of the Extracellular Matrix (ECM) leading to fibrosis?
'ECM Turnover'
Test your knowledge on the warning signs of cancer with this quiz. Learn to recognize changes in bowel or bladder habits, non-healing sores, and other symptoms indicative of potential cancer diagnosis.
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