Medical Biology 5 Altklausuren ähnlich

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What is the primary function of cell communication?

Regulating cellular activities by responding to signals from the environment

In which type of signaling do cells target themselves?

Autocrine signaling

What role do G protein-coupled receptors play in cell communication?

They transmit signals from the cell surface to intracellular targets

Which molecule commonly acts as a second messenger in cell signaling pathways?

$cAMP$ (cyclic Adenosine Monophosphate)

What is the main role of proteases in apoptosis?

They degrade key cellular components

What activates a ligand-gated ion channel?

The activation of G proteins

In hormone signaling, what is the role of the hormone?

To function as a signaling molecule that binds to a receptor

What is the role of a transcription factor in cell signaling?

To regulate the expression of specific genes

What best describes the role of scaffolding proteins in cell signaling?

They organize multiple signaling components into complexes

What role do phosphodiesterases play in cell signaling?

To break down cAMP, thus terminating the signal

In cell signaling, what does negative feedback primarily do?

Prevents over-activation of the pathway

'Downstream' components in cell signaling are involved in:

Involved in steps following the activation of the receptor

What is characteristic of synaptic signaling?

Nerve cells

Intracellular signaling pathways often involve:

Cascades of sequential biochemical reactions

What results from amplification of a signal in cell communication?

An increased response to a small amount of signal

Which process leads to the activation of a protein by adding a phosphate group?

Phosphorylation

What regulates the cell cycle by fluctuations in their levels?

Cyclins and cyclin-dependent kinases

During which process do somatic cells divide?

Budding

Which characteristic is associated with benign tumors?

They are typically cancerous

When does the reduction of chromosome number from diploid to haploid occur?

Mitosis

What crucial role do telomeres play?

Energy production

What accurately describes the role of growth factors in cell division?

They decrease the rate of cell division

What is the main difference between plant and animal cell cytokinesis?

The formation of a cell plate in plants

What is apoptosis?

Programmed cell death

Which enzyme is responsible for DNA replication in cells?

DNA polymerase

What is the significance of the S phase checkpoint in the cell cycle?

It ensures that DNA is properly replicated before mitosis begins

The separation of sister chromatids occurs during which phase of mitosis?

Anaphase

Which protein complex is crucial for the separation of sister chromatids during mitosis?

Anaphase-promoting complex (APC)

During which phase of the cell cycle does the cell grow and synthesize RNA and proteins in preparation for subsequent steps leading to mitosis?

G1 phase

What is the primary purpose of checkpoints in the cell cycle?

To ensure the accurate completion of key processes like DNA replication

In which phase of mitosis do chromosomes decondense and the nuclear envelope re-forms?

Telophase

What is the main function of the mitotic spindle?

Separating sister chromatids and moving them to opposite poles

What is the primary role of a kinase in cell signaling?

To add phosphate groups to proteins

Which process involves the conversion of an extracellular signal to a specific cellular response in a series of steps?

Signal transduction

Intracellular receptors typically bind to:

Gases like oxygen

In which type of cell signaling do cells communicate by direct contact?

Juxtacrine signaling

Phosphatases are enzymes that:

Synthesize ATP

What is the function of ion channel receptors in cell communication?

To allow ions to flow across the membrane in response to a signal

'Cross-talk' in cell communication refers to:

The interaction between different signaling pathways

Which process in cell signaling involves the amplification of the signal?

Signal transduction

'Apoptosis' or programmed cell death can be initiated by:

External signals binding to cell surface receptors

Which type of molecule often acts as an intracellular second messenger in G protein-coupled receptor pathways?

Protein kinases

The specificity of a signaling pathway is often determined by:

The location of the target cell

What is the main function of adhesion receptors in cell communication?

To organize components of the signaling pathway

What is the primary role of a signal cascade in cell signaling?

To amplify the signal and produce a cellular response

In juxtacrine signaling, which type of molecule typically acts as a receptor?

Membrane-bound proteins

How do steroid hormones typically transmit their signal inside a cell?

By binding to intracellular receptors

What is the result of activating a G protein-coupled receptor?

Activation of a signal transduction pathway

Which process in cell signaling involves a relay of signals from the cell surface to target molecules inside the cell?

Signal transduction

What is the main function of a second messenger in cell signaling pathways?

To relay and amplify the signal received by a receptor

'Cross-talk' in cell communication refers to the interaction between:

Different signaling pathways

What is the role of the Ras protein in many signaling pathways?

It functions as a G protein

Which signaling molecule is commonly involved in growth factor signaling?

Insulin

What is involved in the termination of a signaling pathway?

Deactivation or removal of signaling components

What is the effect of a ligand binding to an ion channel receptor?

Change in the permeability of the cell membrane to specific ions

Intracellular signaling pathways often involve:

A series of protein modifications, such as phosphorylation

How does a cell signal often result in immediate response?

Alterations in protein function or enzyme activity

What is the role of cyclic AMP (cAMP) in a cell signaling pathway?

It serves as a secondary messenger relaying signals inside the cell

What is the function of phosphatases in signaling pathways?

Remove phosphate groups from proteins, often leading to inactivation of the signaling pathway

How are cell signaling pathways that rely on phosphorylation events typically regulated?

Kinases and phosphatases

What is the main purpose of the cell cycle?

Cell growth and division

Which phase of the cell cycle is characterized by cell growth and normal metabolic roles?

G1 phase

During which phase of the cell cycle does DNA replication occur?

S phase

What is the function of mitosis in the cell cycle?

Separation of sister chromatids

What occurs during the G2 phase of the cell cycle?

Cell growth and preparation for mitosis

What structure is responsible for the separation of chromosomes during mitosis?

Spindle apparatus

How is cytokinesis in animal cells accomplished?

Constriction of the actin ring

What are cyclins and cyclin-dependent kinases (Cdks)?

Regulatory proteins involved in cell cycle control

What is a characteristic feature of cancer cells?

Loss of contact inhibition

During which process do homologous chromosomes exchange genetic material?

Meiosis I

What is the role of telomeres in chromosomes?

Protecting chromosome ends during replication

Which enzyme is responsible for maintaining telomere length?

Helicase

What does the term 'oncogene' refer to?

A mutated form of a gene involved in normal cell growth, contributing to cancer

What is the primary function of the anaphase-promoting complex/cyclosome (APC/C) in cell division?

Regulating cytokinesis

During which stage of meiosis does synapsis, the pairing of homologous chromosomes, occur?

Prophase I

What does the G1/S checkpoint primarily ensure in cell division?

DNA is undamaged and ready for replication

Which enzyme is crucial for relieving tension in the DNA helix during DNA replication?

Helicase

In which cells does binary fission, a form of cell division, occur?

Fungal cells

What is a kinetochore?

A protein involved in chromosome condensation

What is the primary result of nondisjunction during meiosis?

Cells with an abnormal number of chromosomes

What plays a crucial role in protecting chromosome ends from degradation?

Protecting chromosome ends from degradation

During which stage of mitosis do the nuclear envelope and nucleolus disassemble?

Prophase

What is a characteristic feature of benign tumors?

They are usually encapsulated and grow slowly

What accurately describes the role of growth factors in cell division?

They stimulate cells to divide

What is the result of uncontrolled cell division?

The formation of tumors

When does the reduction of chromosome number from diploid to haploid occur?

Meiosis I

What is the role of telomeres in chromosomes?

Protecting chromosome ends from degradation

Which of the following accurately describes the role of telomeres?

Protecting chromosome ends from degradation

During which stage of cell division do the nuclear envelope and nucleolus disassemble?

Prophase

What is a characteristic feature of benign tumors?

They are usually encapsulated and grow slowly

What accurately describes the role of growth factors in cell division?

They stimulate cells to divide

What is the result of uncontrolled cell division?

The formation of tumors

Somatic cells divide by the process of:

Mitosis

What is the reduction of chromosome number from diploid to haploid occurs during?

Meiosis I

A centromere is:

A structure that links sister chromatids

Which of the following is a characteristic of benign tumors?

They are usually encapsulated and grow slowly

The cell cycle is regulated by fluctuations in the levels of:

Cyclins and cyclin-dependent kinases

What plays a crucial role in protecting chromosome ends from degradation?

Telomeres

What regulates the cell cycle by fluctuations in their levels?

Cyclins and cyclin-dependent kinases

Test your knowledge about cancer cells and cell division with this quiz. Questions cover characteristics of cancer cells, crossing over in chromosomes, and the role of centrosomes in cell division.

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