Podcast
Questions and Answers
What is the survival rate of children with brain cancer?
What is the survival rate of children with brain cancer?
Which of the following is NOT a risk factor for brain cancer?
Which of the following is NOT a risk factor for brain cancer?
What is the most common sign or symptom of brain cancer in adults?
What is the most common sign or symptom of brain cancer in adults?
What is the primary treatment for brain cancer?
What is the primary treatment for brain cancer?
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What is the name of the diagnostic test where dye is injected into blood vessels in the brain?
What is the name of the diagnostic test where dye is injected into blood vessels in the brain?
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What are some risk factors for colon and rectum cancer?
What are some risk factors for colon and rectum cancer?
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Which of the following is a sign or symptom of Type 1 and Type 2 diabetes?
Which of the following is a sign or symptom of Type 1 and Type 2 diabetes?
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What are the risk factors for Type 1 Diabetes?
What are the risk factors for Type 1 Diabetes?
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Which of the following is NOT a risk factor for Type 2 Diabetes?
Which of the following is NOT a risk factor for Type 2 Diabetes?
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Which of the following is a treatment option for breast cancer?
Which of the following is a treatment option for breast cancer?
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What is a possible sign or symptom of colon and rectum cancer?
What is a possible sign or symptom of colon and rectum cancer?
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What type of colon and rectum cancer is hereditary non-polyposis colon cancer?
What type of colon and rectum cancer is hereditary non-polyposis colon cancer?
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What type of colonoscopy is performed in a doctor's office and examines the lowest part of the colon?
What type of colonoscopy is performed in a doctor's office and examines the lowest part of the colon?
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What is the most preferred colon cancer detection test?
What is the most preferred colon cancer detection test?
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What is the recommended age to begin getting regular colonoscopies?
What is the recommended age to begin getting regular colonoscopies?
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What is a stoma?
What is a stoma?
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What kind of diabetes is caused by hormonal changes during pregnancy?
What kind of diabetes is caused by hormonal changes during pregnancy?
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Which of the following is TRUE about diabetes?
Which of the following is TRUE about diabetes?
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What is the role of insulin in the body?
What is the role of insulin in the body?
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What is the primary source of energy for the body?
What is the primary source of energy for the body?
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What is the estimated 5-year survival rate for Non-Hodgkin's Lymphoma?
What is the estimated 5-year survival rate for Non-Hodgkin's Lymphoma?
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Which type of leukemia has a higher survival rate in children compared to adults?
Which type of leukemia has a higher survival rate in children compared to adults?
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What is the main treatment for most types of leukemia?
What is the main treatment for most types of leukemia?
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Which type of lung cancer is characterized by larger cells that grow slower?
Which type of lung cancer is characterized by larger cells that grow slower?
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Which of the following is a common symptom of both Hodgkin's and Non-Hodgkin's Lymphoma?
Which of the following is a common symptom of both Hodgkin's and Non-Hodgkin's Lymphoma?
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What type of treatment involves the use of high-energy rays to shrink or kill cancer cells?
What type of treatment involves the use of high-energy rays to shrink or kill cancer cells?
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Which type of MS has the longest life expectancy?
Which type of MS has the longest life expectancy?
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Which of the following is a risk factor for both lung cancer and lymphoma?
Which of the following is a risk factor for both lung cancer and lymphoma?
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What is the estimated number of new cases of lung cancer diagnosed each year in the US?
What is the estimated number of new cases of lung cancer diagnosed each year in the US?
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Which of these is a common characteristic of Hodgkin's Lymphoma?
Which of these is a common characteristic of Hodgkin's Lymphoma?
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Which type of stem cell transplant uses the patient's own stem cells?
Which type of stem cell transplant uses the patient's own stem cells?
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What is the main imaging tool used for early detection of lung cancer?
What is the main imaging tool used for early detection of lung cancer?
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What is the name of the radioactive gas that can cause lung cancer when breathed in high levels?
What is the name of the radioactive gas that can cause lung cancer when breathed in high levels?
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Which of the following is a treatment option for both leukemia and lung cancer?
Which of the following is a treatment option for both leukemia and lung cancer?
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Which of the following is NOT a risk factor for dementia?
Which of the following is NOT a risk factor for dementia?
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What is the primary goal of treatment for Type 1 diabetes?
What is the primary goal of treatment for Type 1 diabetes?
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What is the main test used to confirm a diagnosis of diabetes?
What is the main test used to confirm a diagnosis of diabetes?
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Which dementia type is NOT associated with a reduced life expectancy?
Which dementia type is NOT associated with a reduced life expectancy?
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What is a common sign or symptom of leukemia?
What is a common sign or symptom of leukemia?
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Which of these statements about Endometriosis is TRUE?
Which of these statements about Endometriosis is TRUE?
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Which of these is NOT a common treatment option for Endometriosis?
Which of these is NOT a common treatment option for Endometriosis?
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Which of these is NOT a risk factor for Heart Disease?
Which of these is NOT a risk factor for Heart Disease?
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What is the main difference between Acute and Chronic Leukemia?
What is the main difference between Acute and Chronic Leukemia?
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Which of the following is a treatment option for heart disease that involves opening up blocked coronary arteries?
Which of the following is a treatment option for heart disease that involves opening up blocked coronary arteries?
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What is the main difference between Type 1 and Type 2 diabetes?
What is the main difference between Type 1 and Type 2 diabetes?
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Which type of dementia is most common?
Which type of dementia is most common?
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Which of the following is NOT a common sign or symptom of Dementia?
Which of the following is NOT a common sign or symptom of Dementia?
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What is the approximate percentage of women who are diagnosed with Endometriosis?
What is the approximate percentage of women who are diagnosed with Endometriosis?
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Which of the following is NOT a non-pharmacological therapy for dementia?
Which of the following is NOT a non-pharmacological therapy for dementia?
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What is a common risk factor for both diabetes and heart disease?
What is a common risk factor for both diabetes and heart disease?
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Which of the following is a sign or symptom of colon cancer that is often experienced by patients?
Which of the following is a sign or symptom of colon cancer that is often experienced by patients?
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Which of the following is a risk factor for colon cancer?
Which of the following is a risk factor for colon cancer?
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Which of the following is a diagnostic test for colon cancer?
Which of the following is a diagnostic test for colon cancer?
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What is the 5-year survival rate for colon cancer when it has metastasized?
What is the 5-year survival rate for colon cancer when it has metastasized?
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What is the most common type of colon cancer?
What is the most common type of colon cancer?
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Which of the following is a type of colon cancer that is characterized by the presence of numerous polyps throughout the colon?
Which of the following is a type of colon cancer that is characterized by the presence of numerous polyps throughout the colon?
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Which of the following is a risk factor for ovarian cancer?
Which of the following is a risk factor for ovarian cancer?
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What tumor marker is used in the early detection of ovarian cancer?
What tumor marker is used in the early detection of ovarian cancer?
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What is the nickname for ovarian cancer?
What is the nickname for ovarian cancer?
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Which of the following is a surgical procedure used to treat ovarian cancer?
Which of the following is a surgical procedure used to treat ovarian cancer?
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Which of the following is a sign or symptom of pancreatic cancer?
Which of the following is a sign or symptom of pancreatic cancer?
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What is the 5-year survival rate for pancreatic cancer?
What is the 5-year survival rate for pancreatic cancer?
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Which of the following is a risk factor for pancreatic cancer?
Which of the following is a risk factor for pancreatic cancer?
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Which of the following is a common treatment for pancreatic cancer?
Which of the following is a common treatment for pancreatic cancer?
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Which of the following is a new chemotherapy pill that is used to treat pancreatic cancer?
Which of the following is a new chemotherapy pill that is used to treat pancreatic cancer?
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What is the most common syndrome linked to brain or spinal cord tumors?
What is the most common syndrome linked to brain or spinal cord tumors?
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Which type of testicular cancer is more common in men in their 40s and 50s?
Which type of testicular cancer is more common in men in their 40s and 50s?
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Which of the following is a risk factor for testicular cancer?
Which of the following is a risk factor for testicular cancer?
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Which of the following treatments is NOT used for melanoma?
Which of the following treatments is NOT used for melanoma?
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Which of the following is TRUE about testicular cancer?
Which of the following is TRUE about testicular cancer?
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What is the survival rate for those with localized, early-stage brain cancer?
What is the survival rate for those with localized, early-stage brain cancer?
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What is the approximate number of new cases of testicular cancer diagnosed annually?
What is the approximate number of new cases of testicular cancer diagnosed annually?
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Which of the following is NOT a common symptom of testicular cancer?
Which of the following is NOT a common symptom of testicular cancer?
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What does the term 'orchidectomy' refer to?
What does the term 'orchidectomy' refer to?
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What is the main advantage of Mohs surgery for skin cancer?
What is the main advantage of Mohs surgery for skin cancer?
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Which of the following is a type of brain tumor?
Which of the following is a type of brain tumor?
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Which of the following is NOT a potential side effect of brain tumor treatment?
Which of the following is NOT a potential side effect of brain tumor treatment?
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Which type of brain tumor almost always occurs on both sides of the head?
Which type of brain tumor almost always occurs on both sides of the head?
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What is the survival rate for people with testicular cancer after 5 years?
What is the survival rate for people with testicular cancer after 5 years?
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What is the main treatment approach for brain tumors? (Select all that apply)
What is the main treatment approach for brain tumors? (Select all that apply)
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Which of these factors is NOT associated with an increased risk of prostate cancer?
Which of these factors is NOT associated with an increased risk of prostate cancer?
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What is the recommended SPF level for someone with very fair, sensitive skin who will be outdoors for 4 hours?
What is the recommended SPF level for someone with very fair, sensitive skin who will be outdoors for 4 hours?
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Which of the following is a characteristic of Basal Cell Carcinoma (BCC)?
Which of the following is a characteristic of Basal Cell Carcinoma (BCC)?
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Which of these statements is TRUE about the treatment of prostate cancer?
Which of these statements is TRUE about the treatment of prostate cancer?
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Which of the following is NOT a risk factor for melanoma?
Which of the following is NOT a risk factor for melanoma?
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What is the primary function of oxybenzone in sunscreen?
What is the primary function of oxybenzone in sunscreen?
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How does the 'PSA Velocity' factor contribute to prostate cancer diagnosis?
How does the 'PSA Velocity' factor contribute to prostate cancer diagnosis?
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Which of the following is a characteristic of Squamous Cell Carcinoma (SCC)?
Which of the following is a characteristic of Squamous Cell Carcinoma (SCC)?
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Which of the following is a treatment for prostate cancer that DOES NOT directly remove or destroy prostate tissue?
Which of the following is a treatment for prostate cancer that DOES NOT directly remove or destroy prostate tissue?
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The 'ABCDE' rule for early melanoma detection focuses on which characteristic?
The 'ABCDE' rule for early melanoma detection focuses on which characteristic?
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Flashcards
Brain Cancer Symptoms (Children)
Brain Cancer Symptoms (Children)
Headache, nausea, vomiting, blurred/double vision, difficulty walking, seizures.
Brain Cancer Symptoms (Adults)
Brain Cancer Symptoms (Adults)
Headache, nausea, vomiting, personality changes, drowsiness/coma, speech problems.
Risk Factors for Brain Cancer
Risk Factors for Brain Cancer
Includes neurofibromatosis, chemical exposure, viruses, head trauma, and family history.
Detection Methods for Brain Cancer
Detection Methods for Brain Cancer
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Breast Cancer Statistics
Breast Cancer Statistics
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Oral Glucose Tolerance Test
Oral Glucose Tolerance Test
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HbA1c Test
HbA1c Test
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Type 1 Diabetes Treatment
Type 1 Diabetes Treatment
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Type 2 Diabetes Risk Reduction
Type 2 Diabetes Risk Reduction
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Gestational Diabetes Care
Gestational Diabetes Care
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Signs of Dementia
Signs of Dementia
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Alzheimer’s Disease
Alzheimer’s Disease
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Vascular Dementia
Vascular Dementia
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Dementia Life Expectancy
Dementia Life Expectancy
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Endometriosis Symptoms
Endometriosis Symptoms
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Heart Disease Symptoms
Heart Disease Symptoms
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Blood Tests for Heart Disease
Blood Tests for Heart Disease
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Leukemia Categories
Leukemia Categories
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Common Childhood Leukemia
Common Childhood Leukemia
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Risk Factors for Leukemia
Risk Factors for Leukemia
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Breast Cancer Symptoms
Breast Cancer Symptoms
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BRCA1 and BRCA2
BRCA1 and BRCA2
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Mammogram
Mammogram
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Lumpectomy
Lumpectomy
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Colon Cancer Signs
Colon Cancer Signs
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Risk Factors for Colon Cancer
Risk Factors for Colon Cancer
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Colonoscopy
Colonoscopy
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Type 1 Diabetes
Type 1 Diabetes
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Type 2 Diabetes
Type 2 Diabetes
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Gestational Diabetes
Gestational Diabetes
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Insulin
Insulin
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Symptoms of Diabetes
Symptoms of Diabetes
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Fecal Occult Blood Test
Fecal Occult Blood Test
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Colostomy
Colostomy
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Leukemia
Leukemia
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Stem Cell Transplant
Stem Cell Transplant
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Chemotherapy
Chemotherapy
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Immunotherapy
Immunotherapy
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Early Detection of Leukemia
Early Detection of Leukemia
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Lung Cancer Types
Lung Cancer Types
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Lobectomy
Lobectomy
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Symptoms of Lung Cancer
Symptoms of Lung Cancer
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Risk Factors for Lung Cancer
Risk Factors for Lung Cancer
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Hodgkin's Lymphoma
Hodgkin's Lymphoma
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Non-Hodgkin's Lymphoma
Non-Hodgkin's Lymphoma
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Multiple Sclerosis (MS)
Multiple Sclerosis (MS)
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Treatment for MS
Treatment for MS
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Survival Rates of Cancer
Survival Rates of Cancer
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Oral Cancer Statistics
Oral Cancer Statistics
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Prostate Cancer Statistics
Prostate Cancer Statistics
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Prostate Cancer Symptoms
Prostate Cancer Symptoms
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Risk Factors for Prostate Cancer
Risk Factors for Prostate Cancer
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Lycopene's Role
Lycopene's Role
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PSA Test Function
PSA Test Function
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Prostate Cancer Treatments
Prostate Cancer Treatments
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Survival Rates for Prostate Cancer
Survival Rates for Prostate Cancer
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Types of Skin Cancer
Types of Skin Cancer
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ABCDE for Skin Cancer Detection
ABCDE for Skin Cancer Detection
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SPF Importance
SPF Importance
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Characteristics of Melanoma
Characteristics of Melanoma
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Excisional Surgery
Excisional Surgery
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Mohs Surgery
Mohs Surgery
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Cryosurgery
Cryosurgery
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Radiation Therapy
Radiation Therapy
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Melanoma Survival Rate
Melanoma Survival Rate
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Testicular Cancer Statistics
Testicular Cancer Statistics
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Seminoma vs Non-seminoma
Seminoma vs Non-seminoma
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Testicular Self Examination (TSE)
Testicular Self Examination (TSE)
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Orchidectomy
Orchidectomy
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Risk Factors for Testicular Cancer
Risk Factors for Testicular Cancer
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Brain Tumor Survival Rate
Brain Tumor Survival Rate
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Neurofibromatosis Type 1 (NF1)
Neurofibromatosis Type 1 (NF1)
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Symptoms of Brain Tumors
Symptoms of Brain Tumors
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Lumbar Puncture
Lumbar Puncture
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Colorectal Cancer Symptoms
Colorectal Cancer Symptoms
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Colorectal Cancer Risk Factors
Colorectal Cancer Risk Factors
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FAP
FAP
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Lynch Syndrome
Lynch Syndrome
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CA125
CA125
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Ovarian Cancer Symptoms
Ovarian Cancer Symptoms
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Risk Factors for Ovarian Cancer
Risk Factors for Ovarian Cancer
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Pancreatic Cancer Symptoms
Pancreatic Cancer Symptoms
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CA 19-9
CA 19-9
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Whipple Procedure
Whipple Procedure
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5-Year Survival Rate Colorectal Cancer
5-Year Survival Rate Colorectal Cancer
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Oophorectomy
Oophorectomy
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Pancreatic Cancer Risk Factors
Pancreatic Cancer Risk Factors
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Colon Cancer Early Detection
Colon Cancer Early Detection
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Study Notes
Brain Cancer
- New Cases: Approximately 22,850 new cases per year
- Signs and Symptoms (Children): Headache, nausea, vomiting, blurred/double vision, difficulty walking, seizures, difficulty handling objects.
- Signs and Symptoms (Adults): Headache, nausea, vomiting, blurred/double vision, personality changes, drowsiness/coma, facial numbness, speech problems, coma.
- Risk Factors: Neurofibromatosis, gender (males), older age, exposure to chemicals, viruses, family history, allergies, head trauma. Gliomas incidence higher in Caucasians; CMV (cytomegalovirus), cleaning agents.
- Early Detection: Lumbar Puncture (spinal fluid removal), MRI scans, CT or PET scans, Angiograms, blood tests, chest X-rays; identification of symptoms.
- Treatment: Craniotomy (surgical removal), chemo, radiation, MRP (magnetic resonance perfusion, using dye to view blood vessels).
- Survival Rates: Decreases with age. Children: 75% (5-66 year range). Adults: Varies by tumor type, from as low as 4% to as high as 92% (65-92 year range).
Breast Cancer
- New Cases (Women): Approximately 310,720 new cases expected in 2024
- New Cases (Men): Approximately 2,800 new cases expected in 2024
- Mortality Rate Decline in Younger Women: Due to earlier detection and improved treatment.
- Signs and Symptoms: Lump or thickening, changes in size/shape/appearance, nipple discharge (blood or clear fluid), skin changes (redness, dimpling), breast pain (not always present).
- Risk Factors: BRCA1/2 gene mutations, family history, higher estrogen levels, smoking, drinking, obesity, lack of exercise.
- Early Detection: Mammograms (yearly for women over 40), Breast Self Exam (BSE).
- Treatment: Lumpectomy, mastectomy, chemotherapy, radiation therapy, hormone therapy, targeted therapy.
Colon and Rectum Cancer
- New Cases: 152,810 new cases annually
- Mortality Rate: 1 death every 9 minutes (53,010 deaths per year)
- Lifetime Risk: 1 in 10 chance
- Signs and Symptoms: Rectal bleeding, blood in stool, change in bowel habits, incomplete evacuation, smaller stools, cramping, gas, abdominal pain (>2 weeks), vomiting, unexplained anemia, reduced appetite.
- Risk Factors: Polyps (tumor-like growths), familial adenomatous polyposis (FAP, age 5-40), Lynch syndrome (HNPCC), inflammatory bowel disease, physical inactivity, lack of fiber, smoking, obesity, leukemia.
- Early Detection: Sigmoidoscopy, colonoscopy (age 50 or 10 years prior to family member diagnosed), barium enema, fecal occult blood test, stool DNA test.
- Treatment: Colectomy (removal of segment of colon), colostomy (permanent/temporary removal routing of colon), radiation, chemo.
- Survival Rates: 5-year survival: 91% (localized), 64% (adjacent organs), 14% (metastases)
Diabetes
- Type 1: Autoimmune condition where the immune system attacks insulin-producing beta cells in the pancreas. Typically develops in childhood or early adulthood, but can occur at any age.
- Type 2: Body resistance to insulin or pancreas doesn't produce enough insulin. Most common in adults over 45, but seen in children with rising obesity rates; typically slow onset.
- Gestational: Caused by hormonal changes during pregnancy; usually 2nd or 3rd trimester; usually subsides after birth
- Symptoms (Type 1 & 2): Frequent urination, extreme thirst, extreme hunger, weight loss, blurry vision, fatigue/weakness, mood changes, stomach cramps. Gestational diabetes symptoms tend to be more subtle.
- Risk Factors (Type 1): Genetics (e.g., MHC gene), age (4-7, 10-14 most at risk), family history, geography (higher prevalence further from equator).
- Risk Factors (Type 2): Obesity, family history, lack of physical activity, older age, gestational diabetes, and having given birth to a large baby.
- Risk Factors (Gestational): Inactivity, family history of diabetes, high-weight baby, obesity, polycystic ovary syndrome.
- Early Detection: Oral glucose tolerance test, routine blood tests, HbA1c test.
- Diagnosis: Blood tests are primary.
- Treatment: Type 1: Insulin therapy, blood sugar monitoring, diet, exercise. Type 2: Healthy diet, exercise, weight loss, blood sugar monitoring, medications, insulin. Gestational: Healthy diet, exercise, blood sugar monitoring, sometimes insulin/meds.
- Insulin Pump: Small device that delivers regular insulin doses throughout the day.
Dementia
- New Cases: Approximately 10 million new cases globally per year.
- Common Types: Alzheimer's disease (60-70% of cases), Vascular dementia, Younger-onset dementia (5-10%).
- Symptoms: The 4 A's: Amnesia, Aphasia, Apraxia, Agnosia.
- Risk Factors: Age, family history/genetics, high blood pressure, smoking/alcohol, diabetes/obesity, inactivity/poor diet, social isolation/depression.
- Early Detection: Cognitive screening tests (Mini-Mental State Exam), brain imaging (MRI, CT), blood tests, biomarkers.
- Treatment: No cure. Medications may help manage symptoms (e.g., cholinesterase inhibitors, memantine), non-pharmacological treatments (cognitive stimulation, occupational therapy), physical activity, social engagement.
- Life Expectancy Impact: Significant reduction. 4-8 years after diagnosis on average. Can vary by type.
Endometriosis
- Prevalence: Roughly 10% of women experience it.
- Signs and Symptoms: Pelvic pain (worsens during period), severe period pain, pain during intercourse, feeling sick, pain/blood while using the restroom, difficulty conceiving.
- Risk Factors: Dysmenorrhea (painful periods), oligomenorrhea (infrequent periods), family history, early menstruation, short menstrual cycles.
- Early Detection: Difficult. Often diagnosed in late 20s/early adult. Severe pain, family history, and irregular periods can be indicators. Diagnosed through ultrasound, MRI, laparoscopy.
- Treatment: Birth control pills, pain medication, laparoscopy (surgery), menopause.
- Life Expectancy: No impact on overall life expectancy but may increase risks of depression or ectopic pregnancy.
Heart Disease
- New Cases: 30.3 Million
- Signs and Symptoms: Chest pain, shortness of breath, dizziness, fainting, fatigue.
- Risk Factors: Stenosis risk factors (Age, BMI, high cholesterol, metabolic syndrome), smoking, diabetes, obesity.
- Early Detection: Blood tests, chest X-ray, electrocardiogram.
- Treatment: Coumadin (blood thinner), pacemaker (regulates heart beat), cardiac catheterization (tests blood pressure and pressure), angioplasty (opens coronary arteries).
- Life Expectancy Impact: Decreases current life expectancy by 8-10%
Leukemia
- New Cases: 3% of all new cancer cases annually
- Categories: Acute (rapid onset, immediate treatment needed), chronic (slow development, no symptoms for years).
- Adult Types: Chronic Lymphocytic Leukemia (CLL), Acute Myeloid Leukemia (AML).
- Children's Types: Acute Lymphoblastic Leukemia (ALL).
- Acute Characteristics: Fast development; immature blood cells crowd out healthy cells.
- Chronic Characteristics: Slower progression; mature blood cells accumulate.
- ALL: Most common in children (high survival), also in adults. Originates in immature lymphocytes.
- AML: Primarily adults, starts in myeloid cells.
- CLL: Most common chronic leukemia in adults, slow progression often detected through blood tests.
- CML: Common in adults, associated with Philadelphia chromosome, slow progression but may accelerate, requires targeted therapies.
- Signs & Symptoms (general): Fatigue, infections, fever, swollen lymph nodes, easy bruising/bleeding, bone pain.
- Risk Factors: Benzene exposure (industrial chemicals, cigarette smoke), radiation exposure, family history, genetic disorders (Down syndrome).
- Early Detection: Routine blood tests (elevated white blood cells). Watch for persisting symptoms.
- Treatment: Stem cell transplant (autologous, allogenic); chemotherapy, targeted therapy, immunotherapy.
- Survival rates: Vary based on type and individual, but generally high for ALL in children and some chronic types.
Lung Cancer
- New Cases: 226,650 diagnosed/year
- Deaths: 124,730 deaths per year.
- Types: Small cell (13-15% of cases), grows fast, 1 stage; Non-small cell (the most common), grows more slowly, 4 stages
- Signs & Symptoms: Coughing, blood or sputum, chest pain, shortness of breath, wheezing, fatigue, weight loss
- Risk Factors: Asbestos exposure, radon exposure, cigarette smoking (major cause: 80-90% of deaths), second-hand smoke.
- Early Detection: Imaging tools like CT and MRI scans
- Treatment: Lobectomy (lobe removal), surgery, chemotherapy, radiation therapy, targeted therapy.
- Survival: Survival rates are low, with significantly better outlook if diagnosed earlier.
Lymphoma
- New Cases (US): 89,190 new cases annually
- Hodgkin's: Declining cases; curable; diagnosed through Reed-Sternberg cells.Primarily in 15-35 year olds, B lymphocytes; more common in wealthier areas and usually occurs in upper body lymph nodes, spreads methodically.
- Non-Hodgkin's: Doubling incidence; occurs primarily in 45-70 year olds; any lymph cells except B cells; 30 subtypes, usually occurs in lower body lymph nodes, and spreads disorderly.
- Signs & Symptoms (general): Enlarged lymph nodes, drenching night sweats, severe itching, poor appetite, fevers (come and go), anemia, weight loss, bone pain.
- Risk Factors: Agent Orange, reduced immunity, exposure to some infections, organ transplants, HIV, exposure to herbicides and chemicals, Epstein-Barr virus, smoking, drug use. Increasingly common in US, Canada, and Northern Europe; lower rates in Asian populations; high in Caucasian males,Eastern European Jews.
- Treatment: Hodgkin's - more treatable with chemo and radiation; Non-Hodgkin's- early stage chemo/radiation; ( high dose chemo with bone marrow or stem cell transplants for others)
- New Treatment: Hodgkin's vaccine therapy.
- Survival: 5 year survival rates: Hodgkin's - 89%; Non-Hodgkin's - 74%
Multiple Sclerosis
- Prevalence: Over 1.8 million worldwide.
- Signs and Symptoms: Vision loss, pain, fatigue, impaired coordination, tingling/loss of feeling in limbs.
- Risk Factors: Female predominance (3x more common), family history.
- Early Detection: Blurred vision, double vision, fatigue, muscle weakness, can be early onset symptoms
- Treatment: Corticosteroids (IV, oral), plasma exchange (plasmapheresis).
- Life Expectancy Impact: Relapsing MS has the highest longevity, then primary progressive, then secondary progressive.
Oral Cancer (Pharynx Cancer)
- This section appears to include information relevant to colon and rectum cancer, not oral/pharynx cancer. Skipping to the next section.
Ovarian Cancer
- New Cases (US): 19,680
- Mortality Rate: Highest of all gynecological cancers. (Approximately 1 in 72 women; 1 in ~95 women die from ovarian cancer)
- Nickname: "Silent Killer" (because of vague symptoms in early stages).
- Signs and Symptoms: Enlarged abdomen (fluid accumulation), digestive disturbances, rarely-vaginal bleeding, excessive hair growth or painful intercourse (less common)
- Risk Factors: Increases with age (peaks in 80s), no children (nulliparity); having many pregnancies and birth control pills lower the risk, fertility drugs; family history of breast cancer; history of other cancers; BRCA1/2; genetic syndromes. Industrialized nations (except Japan) higher prevalence; tubal ligation or hysterectomy lower risk; breastfeeding longer.
- Early Detection: CA125 (tumor marker), pelvic exams, Pap tests (rarely helpful), transvaginal ultrasound, LPA (new test).
- Treatment: Oophorectomy (removal of ovary/ovaries), radiation, chemo. Advanced stages (common) may require additional steps .
- Survival Rates: 51% overall, 92% if localized, 27% if older, 56% if younger
Pancreatic Cancer
- New Cases: 66,440 new cases yearly, 51,750 deaths per year (6 in 10 over 65)
- Incidence Trend: Increasing 1% yearly
- Cell Type: Primarily affects exocrine digestive function (producing digestive juices, insulin, endocrine hormones)
- Signs & Symptoms (usually advanced): Jaundice, headaches, fatigue, indigestion, nausea, sudden onset of diabetes, abdominal pain (worse with alcohol), abdominal mass, pale stools (less common in early stages).
- Risk Factors: Smoking (2-3x higher risk), male gender, obesity, eating red meat (high fat), family history, chemical exposure (gasoline), alcohol and coffee consumption, diabetes, more common in wealthy countries, H. Pylori exposure, pesticides, dyes, metal refineries, sugar sweetened drinks.
- Early Detection: CA 19-9 (tumor marker), biopsy (usually late), ERCP, ultrasound/CT.
- Treatment: Whipple procedure (pancreas, gall bladder, duodenum, etc. removal), other surgeries, radiation, chemotherapy, palliative care, Tarceva (new chemo pill), ablation (heat/cold), embolization.
- Survival Rates: 5-year survival rate: 13% (often measured in months rather than years)
Prostate Cancer
- New Cases: 299,000 new cases; 2nd leading cause of death in men (1 in 6; 1 in 33 die from it)
- Signs and Symptoms: Weak/intermittent urine flow, urgency to urinate (esp. at night), painful ejaculation, pain/burning on urination, inability to urinate, back/thigh pain, blood in urine
- Risk Factors: Lycopene (in tomatoes, etc.) consumption, frequent ejaculations, trans fats/hydrogenated foods, drug use (steroids), increases with age, smoking, dietary fat, vasectomy, African American highest rate, lower prevalence in Asian descent, possible increase with pesticide exposure.
- Risk Reducing Factors: SELENIUM intake (in Brazil nuts, tuna, beef, chicken, canola oil) + aspirin.
- Early Detection/Diagnosis: PSA (prostate-specific antigen), prostate ultrasound, IGF-1 levels, DRE (digital rectal exam), PSA velocity, PSA density.
- Treatment: "Watchful Waiting" (common for elderly patients), hormone therapy, surgery (prostatectomy), ablative therapies (HIFU, cryotherapy). Provenge (vaccine for advanced prostate cancer).
- Survival Rates: Very high, close to 100% for localized disease within 5 and 10 years, much lower in distant-stage cancers
Skin Cancer
- Types: Basal cell carcinoma (BCC, 80%), squamous cell carcinoma (SCC, 20%), melanoma (less than 1%).
- Signs & Symptoms (General): Most appear on sun-exposed areas (face, ears, lips, hands, back)
- BCC: Tiny bumps with pink surface, painless, center can become sore/bleed, lesions/loss of color, swollen blood vessels in skin, ulcers.
- SCC: Small red lump/skin tag, painless and slowly growing, rough/reddish scaly area, open sore with raised border, firm, dome-shaped growth, wart-like growth, sore/old scar.
- Melanoma: Single dark skin spot, unusual moles, sores, lumps, blemishes, changes in appearance/feel..
- Risk Factors: Moles/Melanocytic nevi (can become cancerous); fair skin, more common in white populations than other racial groups, with incidence increasing with age.
- Prevention: Use high SPF sunscreen (varies by skin tone), reducing exposure to UV rays
- Early Detection: ABCDE (Asymmetry, Border, Color, Diameter, Evolving).
- Treatment: Surgery (excisional, Mohs), curettage, cryosurgery, radiation, cryotherapy.
- Survival: Non-melanoma: high (90%); melanoma survival varies greatly based on stage and if/when it spreads. Decline in death rates observed.
Testicular Cancer
- New Cases: Approx. 10,000 new cases annually.
- Types: Seminoma (slow-growing, men 40s-50s), Non-seminoma (faster-growing, multiple cell types).
- Symptoms: Lump/swelling in testicle, feeling of heaviness in scrotum, dull ache in lower belly/groin, back pain, breast enlargement/tenderness.
- Risk Factors: Family history, young adult males, white males, undescended testicle.
- Early Detection: Testicular Self-Examination (TSE); feeling for lumps or abnormalities in the testicles.
- Treatment: Surgery (orchidectomy), chemotherapy, radiotherapy, lymph node removal (if spread to them).
- Survival: About 95% 5-year survival rate.
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Test your knowledge on cancer, its symptoms, and treatments with this comprehensive quiz. Questions cover brain cancer, colon cancer, and diabetes, focusing on survival rates, risk factors, diagnostics, and treatment options. Ideal for anyone interested in understanding cancer better.