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Questions and Answers
What is the primary characteristic of cancer cells that distinguishes them from normal cells?
What is the term for the spread of cancer cells from their site of origin to other sites within the body?
What is the term for a mass of cancer cells that are derived from a single original cancer cell?
What is the primary way in which cancer cells interfere with normal body processes?
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Why are cancers considered genetic diseases?
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What is the exception to the rule that tumours are a mass of cancer cells?
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What is the consequence of a mutation occurring in the promoter region of a gene?
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What is the estimated percentage of cancers that may originate from chromothripsis events?
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What is the consequence of an insertion or deletion mutation in the coding region of a gene?
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What is the role of error-prone DNA polymerase in gene mutation?
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What is the term for the process by which a large number of genomic rearrangements occur in a single event?
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What is the percentage of the genome that consists of genes?
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What is the primary mechanism that controls cell numbers in the body?
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What is the primary difference between benign and malignant tumours?
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What is the role of angiogenesis in cancer development?
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What is the function of oncogenes in normal cells?
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What is the function of cyclin-dependent kinases (cdks) in the cell cycle?
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What is the result of unlimited replicative potential in cancer cells?
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What is the effect of a mutation in a tumor suppressor gene?
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What is reprogramming of energy metabolism in cancer cells?
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What is the primary cause of death in cancer patients?
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What is the purpose of the G0 phase in the cell cycle?
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What is the function of the cyclin D/cdk4/6 complex in the cell cycle?
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What is the percentage of cancer cases that are inherited?
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What is the primary difference between normal and cancer cells in cell culture?
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What is the effect of disruption of checkpoints in the cell cycle?
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What is the characteristic of the effect of oncogenes on cell growth?
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What is the result of DNA damage in normal cells?
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What is the role of genome instability in cancer development?
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What is the function of p53 in the cell cycle?
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What is a common characteristic of tumor suppressor genes?
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What is the relationship between carcinogens and mutagens?
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What is the role of the Retinoblastoma (Rb) gene in cell cycle regulation?
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What is the function of Ras proteins in signal transduction?
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What is the correlation between UV exposure and cancer?
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What is the result of unrepaired or incorrectly repaired DNA damage?
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What is the role of transcription factors in gene expression?
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What is the function of protein phosphatases in cell signaling?
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What is the result of mutations occurring in genes involved in DNA repair?
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What is the definition of a mutagen?
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What is the consequence of genomic instability in cancer cells?
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What is the role of Cyclins and associated cyclin-dependent kinases in regulating Rb gene activity?
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