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Questions and Answers
Enzyme-linked receptors have intracellular domains that are associated with an enzyme.
Enzyme-linked receptors have intracellular domains that are associated with an enzyme.
True (A)
When a ligand binds to the extracellular domain of an enzyme-linked receptor, the enzyme is directly activated.
When a ligand binds to the extracellular domain of an enzyme-linked receptor, the enzyme is directly activated.
False (B)
The binding of a phosphate group to an amino acid is one of the steps in the activation of a tyrosine kinase receptor.
The binding of a phosphate group to an amino acid is one of the steps in the activation of a tyrosine kinase receptor.
True (A)
G-protein-linked receptors bind directly to an enzyme in the cell membrane.
G-protein-linked receptors bind directly to an enzyme in the cell membrane.
Adenylyl cyclase is an enzyme that converts ATP to cyclic adenosine monophosphate (cAMP).
Adenylyl cyclase is an enzyme that converts ATP to cyclic adenosine monophosphate (cAMP).
CAMP (Cyclic Adenosine Monophosphate) is a derivative of adenosine triphosphate (ATP) and is used for intracellular signal transduction in many different organisms.
CAMP (Cyclic Adenosine Monophosphate) is a derivative of adenosine triphosphate (ATP) and is used for intracellular signal transduction in many different organisms.
There are only two types of G-protein receptors: Gs and Gi.
There are only two types of G-protein receptors: Gs and Gi.
The Gs receptor is an inhibitory G protein that inhibits adenylyl cyclase, thus lowering the level of cAMP in the cell.
The Gs receptor is an inhibitory G protein that inhibits adenylyl cyclase, thus lowering the level of cAMP in the cell.
Diacylglycerol (DAG), produced by phospholipase C (PLC) activated by the Gq receptor, can directly contract and constrict the heart and blood vessels, similar to cAMP.
Diacylglycerol (DAG), produced by phospholipase C (PLC) activated by the Gq receptor, can directly contract and constrict the heart and blood vessels, similar to cAMP.
Inositol triphosphate (IP3), another secondary messenger produced by PLC, mediates intracellular release of calcium, which can result in contraction and constriction.
Inositol triphosphate (IP3), another secondary messenger produced by PLC, mediates intracellular release of calcium, which can result in contraction and constriction.
