10 Questions
What is the result of the interaction between oxidised LDL and INFgamma M1 activation in the early phase of atherosclerotic lesion development?
NETosis of foam cells by contact with histones of DNA trap
What is the consequence of the pro-atherogenic vicious circle between lipids and cell components implicated in the inflammatory process?
All of the above
What is the effect of modified LDL on endothelium?
Pro-inflammatory response
Why are younger males more affected by atherosclerosis?
Due to hormonal reasons
What is the result of the recruitment of BM-derived SMCs progenitor synthesis of proteoglycans?
Advances in the atherosclerotic lesion development
What is the role of smooth muscle cells in the advanced phase of atherosclerotic lesion development?
Participation in the formation of the cap of the plaque
What is the effect of hypertension and smoking on atherosclerosis?
Environmental/Modifiable risk factors
What is the effect of overweight and obesity on atherosclerosis?
Environmental/Modifiable risk factors
What is the reason for the higher incidence of atherosclerosis in African and Asian populations compared to Caucasian populations?
Ethnicity-related factors
What is the result of the formation of fibroblast-like SMCs?
Advances in the atherosclerotic lesion development
Test your knowledge of Calviello metabolic maps, focusing on the structure and progression of atherosclerotic plaques, including the necrotic lesion, fibrous cap, and media.
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