Calcium Channel Blockers Quiz

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Which of the following statements about calcium channel blockers (CCBs) is correct?

Nifedipine and amlodipine do not reduce heart rate and contractility. (correct)

Amlodipine, a long-acting CCB, can cause myocardial hypoperfusion.

Short-acting nifedipine can lead to a sudden drop in blood pressure and reflex tachycardia.

Verapamil and diltiazem have marked effects on arteriolar vasodilatation.

Which of the following statements about potassium channel openers is incorrect?

They are considered first-line therapy for anti-ischemic treatment due to their potent effects. (correct)

They open ATP-sensitive K+ channels, leading to smooth muscle hyperpolarization.

They are chemically related to nitrates and act as weak NO donors, inducing venular dilation.

They inhibit the opening of L-type voltage-gated Ca+2 channels, producing vasodilatation.

Which of the following statements about beta-blockers is correct?

They are chemically related to nitrates and act as weak NO donors.

They decrease heart rate and contractility by blocking calcium channels.

They induce arteriolar vasodilatation by opening potassium channels.

They are considered the first choice for long-term use in reducing the incidence of sudden death. (correct)

Which of the following statements about organic nitrates is correct?

They are NO donors that induce venular dilation and are chemically related to potassium channel openers. (A) Signup and view all the answers

Which of the following statements about pFOX inhibitors is incorrect?

They belong to the same class as beta-blockers and calcium channel blockers. (B) Signup and view all the answers

Which of the following statements about the effects of calcium channel blockers is correct?

Non-dihydropyridines like verapamil and diltiazem have marked effects on arteriolar vasodilatation. (D) Signup and view all the answers

Which of the following statements about calcium channel blockers is correct?

They selectively block L-type calcium channels in vascular smooth muscle cells, leading to vasodilation. (A) Signup and view all the answers

Which of the following is NOT a pharmacological action of calcium channel blockers in the context of angina relief?

Increasing heart rate (+ve chronotropism) (B) Signup and view all the answers

Which of the following statements about organic nitrates is correct?

They cause vasodilation by increasing the production of nitric oxide. (C) Signup and view all the answers

Which of the following is a dihydropyridine calcium channel blocker?

Nifedipine sustained release (B) Signup and view all the answers

Which of the following statements about non-dihydropyridine calcium channel blockers is correct?

They are examples of verapamil and diltiazem. (C) Signup and view all the answers

Which of the following statements about beta-blockers is correct, based on the given information?

They are mentioned as one of the drug classes used for angina treatment. (B) Signup and view all the answers

What is the primary mechanism of action of organic nitrates in the treatment of angina?

Vasodilation of veins, reducing preload and ventricular filling pressure (D) Signup and view all the answers

Which of the following statements about the pharmacological actions of organic nitrates is NOT true?

They inhibit the enzyme $\text{pFOX}$, leading to reduced myocardial oxygen demand (A) Signup and view all the answers

Why are organic nitrates administered via sublingual, buccal, or transdermal routes?

To bypass first-pass metabolism in the liver, ensuring direct systemic arrival of the drugs (D) Signup and view all the answers

Which class of anti-anginal drugs acts by inhibiting calcium entry into vascular smooth muscle cells?

Dihydropyridines (C) Signup and view all the answers

Which of the following mechanisms of action is NOT associated with non-dihydropyridine calcium channel blockers in the treatment of angina?

Activation of protein kinase G (PKG), leading to vascular smooth muscle relaxation (B) Signup and view all the answers

What is the primary mechanism of action of beta-blockers in the treatment of angina?

Negative chronotropic and inotropic effects, reducing myocardial oxygen demand (C) Signup and view all the answers

Calcium Channel Blockers Quiz

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Questions and Answers

Which of the following statements about calcium channel blockers (CCBs) is correct?

Which of the following statements about potassium channel openers is incorrect?

Which of the following statements about beta-blockers is correct?

Which of the following statements about organic nitrates is correct?

Which of the following statements about pFOX inhibitors is incorrect?

Which of the following statements about the effects of calcium channel blockers is correct?

Which of the following statements about calcium channel blockers is correct?

Which of the following is NOT a pharmacological action of calcium channel blockers in the context of angina relief?

Which of the following statements about organic nitrates is correct?

Which of the following is a dihydropyridine calcium channel blocker?

Which of the following statements about non-dihydropyridine calcium channel blockers is correct?

Which of the following statements about beta-blockers is correct, based on the given information?

What is the primary mechanism of action of organic nitrates in the treatment of angina?

Which of the following statements about the pharmacological actions of organic nitrates is NOT true?

Why are organic nitrates administered via sublingual, buccal, or transdermal routes?

Which class of anti-anginal drugs acts by inhibiting calcium entry into vascular smooth muscle cells?

Which of the following mechanisms of action is NOT associated with non-dihydropyridine calcium channel blockers in the treatment of angina?

What is the primary mechanism of action of beta-blockers in the treatment of angina?

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