Calcium Channel Blockers Quiz
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Questions and Answers

What is a key characteristic of L type voltage gated calcium channels?

  • They are activated by hyperpolarization
  • They are permeable to sodium ions
  • They are responsible for the upstroke of the action potential in cardiac myocytes (correct)
  • They are primarily found in skeletal muscle

    • Which of the following is a physiology characteristic of calcium?

  • It has no role in blood clotting
  • It decreases the release of neurotransmitters at synapses
  • It inhibits muscle contraction
  • It acts as a secondary messenger in signal transduction pathways (correct)

    • How do DHP and Non-DHP calcium channel blockers (CCBs) differ?

  • DHP CCBs primarily target cardiac calcium channels
  • DHP CCBs have a stronger effect on smooth muscle cells
  • Non-DHP CCBs are more effective in reducing peripheral vascular resistance (correct)
  • Non-DHP CCBs are contraindicated in hypertension

    • In the context of calcium channel blockers (CCBs), which factor is included in the pharmacokinetic profile?

    <p>Route of administration</p> Signup and view all the answers

    What condition should be considered when deciding to use or avoid calcium channel blockers (CCBs)?

    <p>Bronchospastic lung disease</p> Signup and view all the answers

    What is a key characteristic of L type voltage gated calcium channels?

    <p>They are activated by depolarization</p> Signup and view all the answers

    Which factor is NOT typically a pharmacokinetic profile detail of calcium channel blockers (CCBs)?

    <p>Cardiac contractility effect</p> Signup and view all the answers

    What is a common adverse drug reaction (ADR) associated with calcium channel blockers (CCBs)?

    <p>Hyperglycemia</p> Signup and view all the answers

    Which of the following conditions is important to consider when deciding to use or avoid calcium channel blockers (CCBs)?

    <p>Hypotension</p> Signup and view all the answers

    What effect do calcium channel blockers (CCBs) have on coronary blood flow?

    <p>Increase coronary blood flow</p> Signup and view all the answers

    What is a key characteristic of L type voltage gated calcium channels?

    <p>They are primarily found in the heart</p> Signup and view all the answers

    Which factor is NOT typically a pharmacokinetic profile detail of calcium channel blockers (CCBs)?

    <p>First-pass metabolism</p> Signup and view all the answers

    How do dihydropyridine (DHP) and non-dihydropyridine (Non-DHP) calcium channel blockers (CCBs) differ?

    <p>Non-DHPs have a greater vasodilatory effect on coronary arteries</p> Signup and view all the answers

    What condition should be considered when deciding to use or avoid calcium channel blockers (CCBs)?

    <p>Asthma</p> Signup and view all the answers

    What effect do calcium channel blockers (CCBs) have on plasma renin?

    <p>Decrease plasma renin levels</p> Signup and view all the answers

    What is a distinguishing feature of L type voltage-gated calcium channels?

    <p>They are activated by depolarization</p> Signup and view all the answers

    Which condition should generally be avoided when considering the use of calcium channel blockers (CCBs)?

    <p>Severe bradycardia</p> Signup and view all the answers

    What effect do calcium channel blockers (CCBs) typically have on cardiac contractility?

    <p>Decrease it</p> Signup and view all the answers

    In terms of pharmacokinetics, which detail is often associated with dihydropyridine (DHP) calcium channel blockers?

    <p>High bioavailability</p> Signup and view all the answers

    What is a possible effect of calcium channel blockers (CCBs) on left ventricular hypertrophy?

    <p>Reducing hypertrophy</p> Signup and view all the answers

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