Calcitonin: Osteoporosis and Hypercalcemia Treatment
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Questions and Answers

A nurse is teaching a client how to self-administer intranasal calcitonin. Which instruction should the nurse include?

  • Use the same nostril for each administration to ensure consistent absorption.
  • Store the medication at room temperature away from light.
  • Administer the spray while lying down to prevent nasal irritation.
  • Prime the pump of the new container prior to the first use. (correct)

A client taking calcitonin reports tingling in their fingers and muscle spasms. What is the priority action for the nurse?

  • Instruct the client to monitor the adverse effect.
  • Advise the client to reduce their sodium consumption.
  • Instruct the client to notify their provider immediately. (correct)
  • Instruct the client to increase their potassium intake.

A client with a history of salmon allergy is prescribed calcitonin. What is the most appropriate nursing action?

  • Administer a test dose of calcitonin and monitor for a reaction.
  • Administer the medication with epinephrine available.
  • Educate the client about potential side effects.
  • Confirm that this is a safe medication with the provider due to the allergy. (correct)

A client is prescribed both lithium and calcitonin. What nursing intervention is most important?

<p>Monitoring serum lithium levels. (C)</p> Signup and view all the answers

A client has been taking calcitonin for 2 years. What assessment is most important for the nurse to monitor?

<p>Bone density studies. (B)</p> Signup and view all the answers

Which of the following instructions regarding calcitonin administration should the nurse include when teaching a client?

<p>Alternate nostrils daily when using the intranasal form. (B)</p> Signup and view all the answers

A postmenopausal client is prescribed calcitonin. What dietary instruction is most important for the nurse to emphasize?

<p>Consume a diet high in calcium and vitamin D. (C)</p> Signup and view all the answers

A client is receiving calcitonin via subcutaneous injection. What action promotes client safety?

<p>Rotating injection sites with each dose. (B)</p> Signup and view all the answers

A client with hyperparathyroidism is prescribed calcitonin. What is the primary expected outcome of this medication in this client?

<p>Decreased serum calcium levels by promoting calcium excretion. (B)</p> Signup and view all the answers

Which of the following assessment findings would warrant withholding calcitonin and notifying the healthcare provider?

<p>Erythema observed at the intradermal allergy test site within 10 minutes. (B)</p> Signup and view all the answers

A client is prescribed injectable calcitonin salmon. Which instruction should the nurse include in the client's teaching plan regarding potential adverse effects?

<p>&quot;Be aware that polyuria is a potential side effect, so stay well-hydrated.&quot; (D)</p> Signup and view all the answers

A client is prescribed calcitonin for long-term management of osteoporosis. What should the nurse emphasize to maximize the therapeutic effects of the medication?

<p>Maintain a diet rich in calcium and vitamin D. (C)</p> Signup and view all the answers

When administering calcitonin nasal spray to a client, what is the most important action for the nurse to take prior to administration?

<p>Assess the client's nostrils for irritation or ulceration. (B)</p> Signup and view all the answers

A nurse is caring for a client receiving calcitonin. Which of the following findings would indicate a therapeutic effect of the medication?

<p>Decrease in serum calcium level. (B)</p> Signup and view all the answers

A client with a known fish allergy is prescribed calcitonin salmon. What is the most appropriate nursing action?

<p>Contact the healthcare provider to discuss an alternative medication. (C)</p> Signup and view all the answers

A client receiving calcitonin reports tingling in their fingers and toes. Which electrolyte imbalance should the nurse suspect?

<p>Hypocalcemia (A)</p> Signup and view all the answers

Flashcards

Calcitonin

A hormone that decreases bone resorption, used to treat osteoporosis, hypercalcemia, and Paget's disease.

Calcitonin's Action

Inhibits osteoclasts to prevent bone breakdown and increases calcium excretion.

Calcitonin Contraindications

Clients with salmon protein or gelatin allergies.

Hypocalcemia Signs

Muscle spasms, tingling, and low serum calcium levels.

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Calcitonin Diet

High calcium and vitamin D intake.

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Calcitonin Allergy Test

Check for erythema within 15 minutes.

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Calcitonin Nasal Spray Side Effects

Nasal dryness, irritation, headaches, and epistaxis.

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Calcitonin Injectable Form Side Effects

Injection site reactions, nausea, vomiting, and polyuria.

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Intranasal Calcitonin Administration

Hold upright and prime before first use. Alternate nostrils daily.

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Subcutaneous/Intramuscular Calcitonin Administration

Rotate injection sites to avoid irritation and tissue damage.

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Calcitonin Storage

Keep away from light and refrigerate to maintain potency.

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Importance of Client Teaching (Calcitonin)

Allows self-administration, early detection of side effects, and monitoring effectiveness.

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Calcitonin - Reportable Side Effects

Report nasal irritation/bleeding, rash/itching, or muscle spasms/tingling.

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Calcitonin - Diet and Monitoring

A diet high in calcium and vitamin D supports bone health; calcitonin may lose effectiveness over time.

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Calcitonin-Lithium Interaction

Calcitonin may decrease serum lithium levels, requiring close monitoring.

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Study Notes

  • Calcitonin cannot prevent osteoporosis, unlike SERMs, bisphosphonates, and calcium supplements
  • It treats established postmenopausal osteoporosis, hypercalcemia (secondary to hyperparathyroidism), and Paget’s disease

Prototype Medication

  • Calcitonin salmon is the prototype and only medication in its classification

Medication Classification

  • Hypocalcemic

Expected Pharmacologic Action

  • Decreases bone resorption
  • Functions similarly to calcitonin produced by the thyroid gland
  • Inhibits osteoclasts, preventing bone tissue breakdown
  • Increases calcium excretion
  • Decreases serum calcium in clients with hypercalcemia

Adverse Drug Reactions

  • Hypersensitivity reactions and anaphylaxis in clients with salmon protein or gelatin diluent allergies
  • Hypocalcemia if calcium excretion exceeds intake
  • Nasal dryness and irritation, headaches, and epistaxis with the nasal form
  • Injection site reactions, nausea, vomiting, and polyuria with the injectable form
  • Decreased therapeutic effects with long-term use

Interventions

  • Assess nostrils for irritation or ulceration before intranasal administration
  • Monitor for hypocalcemia manifestations like muscle spasms and tingling in fingers/toes, and check serum calcium levels
  • Provide a diet high in calcium and vitamin D when treating osteoporosis with calcitonin salmon
  • Perform an intradermal allergy test before therapy

Safety Alert

  • Anaphylactic shock can occur in clients allergic to salmon or fish protein
  • Erythema development within 15 minutes in allergy test indicates sensitivity: Withhold the medication if this occurs
  • Even without an allergic reaction, keep antihistamines, oxygen, and epinephrine (1:1000 concentration) available during the first few days of therapy

Administration

  • Hold the nasal pump upright when administering intranasally
  • Prime the pump before first use by following the manufacturer’s instructions
  • Spray once in a nostril, alternating nostrils daily
  • Rotate injection sites for subcutaneous or intramuscular administration
  • Protect parenteral calcitonin from light and refrigerate it

Client Instructions

  • Self-administer calcitonin properly (especially intranasally)
  • Prime the pump for each new container before first use, following the manufacturer’s instructions
  • Alternate nostrils daily during administration
  • Report nasal irritation or bleeding
  • Immediately notify provider if rash, itching, muscle spasms, or tingling of fingers/toes occurs
  • Consume a diet high in calcium and vitamin D
  • Calcitonin may lose effectiveness after a year or more of use, so regular bone density studies are needed

Contraindications and Precautions

  • Contraindicated in clients allergic to salmon or other fish protein

Interactions

  • Calcitonin may decrease serum lithium levels in clients taking lithium, so monitor lithium levels closely
  • Previous bisphosphonate treatment (alendronate, risedronate, etidronate, ibandronate, or pamidronate) may decrease the body's response to calcitonin

Question Answer

  • When considering the adverse effects of calcitonin, the nurse should instruct the client to increase calcium and vitamin D intake.

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Description

Calcitonin, a hypocalcemic medication, is used to treat established postmenopausal osteoporosis, hypercalcemia, and Paget’s disease. It inhibits osteoclasts, reducing bone resorption and increasing calcium excretion. Adverse effects include hypersensitivity reactions, hypocalcemia, nasal issues, injection site reactions, nausea, vomiting and polyuria.

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