Podcast
Questions and Answers
Which complement components bind to specific receptors on erythrocytes, neutrophils, monocytes, and macrophages to facilitate phagocytosis?
Which complement components bind to specific receptors on erythrocytes, neutrophils, monocytes, and macrophages to facilitate phagocytosis?
C4b, C3b, and iC3b
What is the consequence of binding C5a to monocytes?
What is the consequence of binding C5a to monocytes?
Oxidative burst with increased production of hydrolytic enzymes
List three cases where complement can be harmful.
List three cases where complement can be harmful.
- Gram-negative septicaemia, 2. Tissue necrosis like myocardial infarction, 3. Lysis of red cells
What is the main function of the Membrane Inhibitor of Reactive Lysis (MIRL)?
What is the main function of the Membrane Inhibitor of Reactive Lysis (MIRL)?
What prevents lysis from occurring despite the binding of C8 and C9?
What prevents lysis from occurring despite the binding of C8 and C9?
What is another name for the S protein?
What is another name for the S protein?
What is the significance of the activation of complement in biological manifestations?
What is the significance of the activation of complement in biological manifestations?
Where is the Membrane Inhibitor of Reactive Lysis (MIRL) widely distributed?
Where is the Membrane Inhibitor of Reactive Lysis (MIRL) widely distributed?
What is the role of complement receptors found on host cells?
What is the role of complement receptors found on host cells?
What does the S protein interact with as it forms in the fluid phase?
What does the S protein interact with as it forms in the fluid phase?
What does the Membrane Inhibitor of Reactive Lysis (MIRL) prevent from forming?
What does the Membrane Inhibitor of Reactive Lysis (MIRL) prevent from forming?
What are the consequences of binding C5a to monocytes?
What are the consequences of binding C5a to monocytes?
What serves as a means of linking innate and natural immunity?
What serves as a means of linking innate and natural immunity?