Buspirone: Uses, Mechanism of Action, and Metabolism

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9 Questions

What is the primary elimination mechanism of buspirone?

Oxidative metabolism

Which receptor is buspirone known to bind optimally to?

Serotonin receptor

Which of the following compounds has similar potency as buspirone?

1-pyrimidinylpiperazine

What type of inhibitor can block the formation of major buspirone metabolites?

CYP3A inhibitor

What alkyl spacer length is typically observed in buspirone analogs?

Chain of 2-5 methylene groups

What is the typical aryl portion in buspirone analogs?

Phenyl, substituted phenyl, or a heteroaryl group

What is the analysis method used to determine the amount of buspirone present in a sample?

Spectrophotometric analysis

What color is produced due to the oxidation reaction of buspirone with alkaline potassium permanganate?

Bluish green

Which atom is typically found in the terminus of buspirone analogs?

Nitrogen

This quiz covers the uses of Buspirone in treating generalized anxiety disorder, its mechanism of action for managing anxiety symptoms, and its metabolism through oxidative pathways. Test your knowledge on this anti-anxiety medication.

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