Podcast
Questions and Answers
In which zone of the lung does no blood flow occur?
In which zone of the lung does no blood flow occur?
What is the defining characteristic of Zone 1 in terms of blood flow?
What is the defining characteristic of Zone 1 in terms of blood flow?
Which pressure is always greater in the pulmonary circulation in relation to pulmonary venous pressure?
Which pressure is always greater in the pulmonary circulation in relation to pulmonary venous pressure?
Under what conditions can Zone 1 occur?
Under what conditions can Zone 1 occur?
Signup and view all the answers
What effect does high alveolar pressures have on pulmonary blood flow?
What effect does high alveolar pressures have on pulmonary blood flow?
Signup and view all the answers
In which lung zone is there continuous blood flow?
In which lung zone is there continuous blood flow?
Signup and view all the answers
What percentage of Cardiac Output does the Bronchial Circulation account for?
What percentage of Cardiac Output does the Bronchial Circulation account for?
Signup and view all the answers
Where is the alveolar pressure highest compared to arterial pressure, resulting in no forward blood flow?
Where is the alveolar pressure highest compared to arterial pressure, resulting in no forward blood flow?
Signup and view all the answers
Why might new vessels branch from the bronchial veins?
Why might new vessels branch from the bronchial veins?
Signup and view all the answers
During exercise and when recumbent, which lung zone exhibits recruitment due to gravity?
During exercise and when recumbent, which lung zone exhibits recruitment due to gravity?
Signup and view all the answers
What is the average diameter of pulmonary capillaries?
What is the average diameter of pulmonary capillaries?
Signup and view all the answers
Where is pulmonary capillary wedge pressure (PCWP) typically measured within the lung?
Where is pulmonary capillary wedge pressure (PCWP) typically measured within the lung?
Signup and view all the answers
How long does a red blood cell (RBC) take to travel through the pulmonary capillaries at resting Cardiac Output?
How long does a red blood cell (RBC) take to travel through the pulmonary capillaries at resting Cardiac Output?
Signup and view all the answers
Which lung zone maintains a matching balance between pulmonary blood flow and ventilation under normal conditions?
Which lung zone maintains a matching balance between pulmonary blood flow and ventilation under normal conditions?
Signup and view all the answers
What is the primary function of Pulmonary Circulation?
What is the primary function of Pulmonary Circulation?
Signup and view all the answers
How many functional pulmonary capillaries are there that supply 300 million alveoli in the lungs?
How many functional pulmonary capillaries are there that supply 300 million alveoli in the lungs?
Signup and view all the answers
What causes compression or collapse of vessels due to negative transmural pressure differences?
What causes compression or collapse of vessels due to negative transmural pressure differences?
Signup and view all the answers
Why is pulmonary vascular resistance (PVR) usually 1/10 systemic vascular resistance (SVR)?
Why is pulmonary vascular resistance (PVR) usually 1/10 systemic vascular resistance (SVR)?
Signup and view all the answers
At high lung volumes, what happens to the resistance of alveolar vessels?
At high lung volumes, what happens to the resistance of alveolar vessels?
Signup and view all the answers
What is the relationship between lung volume and extra-alveolar vessel resistance?
What is the relationship between lung volume and extra-alveolar vessel resistance?
Signup and view all the answers
How does the location of alveolar vessels affect their resistance?
How does the location of alveolar vessels affect their resistance?
Signup and view all the answers
What happens to pulmonary vascular resistance (PVR) during exercise with increased cardiac output?
What happens to pulmonary vascular resistance (PVR) during exercise with increased cardiac output?
Signup and view all the answers
What causes the decrease in pulmonary vascular resistance (PVR) with increased pulmonary blood flow?
What causes the decrease in pulmonary vascular resistance (PVR) with increased pulmonary blood flow?
Signup and view all the answers
In the lungs, where does pulmonary edema typically first occur according to Starling's forces?
In the lungs, where does pulmonary edema typically first occur according to Starling's forces?
Signup and view all the answers
Why does hypoxic pulmonary vasoconstriction (HPV) occur?
Why does hypoxic pulmonary vasoconstriction (HPV) occur?
Signup and view all the answers
How does gravity affect blood flow in the lungs?
How does gravity affect blood flow in the lungs?
Signup and view all the answers
How does HPV help mitigate shunt in the lungs?
How does HPV help mitigate shunt in the lungs?
Signup and view all the answers
What happens to arterioles supplying hypoxic alveoli during HPV?
What happens to arterioles supplying hypoxic alveoli during HPV?
Signup and view all the answers
How do anesthetic gases affect the HPV response?
How do anesthetic gases affect the HPV response?
Signup and view all the answers
What is the role of O2-sensitive voltage-gated K+ channels in HPV?
What is the role of O2-sensitive voltage-gated K+ channels in HPV?
Signup and view all the answers
What is the main purpose of hypoxic pulmonary vasoconstriction (HPV)?
What is the main purpose of hypoxic pulmonary vasoconstriction (HPV)?
Signup and view all the answers
