Bronchodilators: β2-agonists in Asthma Treatment

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12 Questions

What is the recommended way to use ULTRA-LONG ACTING β2—AGONISTS for asthma treatment?

In combination with an ICS

How long do ULTRA-LONG ACTING β2—AGONISTS provide bronchodilating effects for?

12 hours

Which beverage provides stimulant effects due to containing methylxanthines?

Coffee

What is the main mechanism of action by which methylxanthines cause bronchodilation?

Inhibition of phosphodiesterase

Which of the following medications should NOT be used as monotherapy for asthma?

Arformoterol

What is the most likely outcome associated with using ULTRA-LONG ACTING β2—AGONISTS as monotherapy for asthma?

Increased mortality rate

What is the primary use of short-acting β2-agonists?

Symptomatic treatment of bronchospasm

What is the mechanism of action of β2-agonists?

Stimulation of GPCRs leading to increased cAMP

What is the duration of action of short-acting β2-agonists?

4-6 hours

What is the benefit of administering β2-agonists by inhalation?

It reduces systemic toxicity

What is the example of a short-acting β2-agonist?

Salbutamol

What is the use of long-acting β2-agonists?

Adjunctive therapy for moderate to severe asthma

Learn about the mainstay treatment for asthma involving β2-agonists, including their uses and mechanism of action. Explore the two categories of β2-adrenoceptor agonists used in asthma treatment.

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