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Questions and Answers
Which bronchodilator was found to be more effective in relieving dyspnea and had a quicker onset of action compared to ipratropium bromide in a study?
Which bronchodilator was found to be more effective in relieving dyspnea and had a quicker onset of action compared to ipratropium bromide in a study?
- Terbutaline
- Albuterol (correct)
- Salbutamol
- Fenoterol
Which short-acting beta2-agonist was taken off the market in many countries due to its adverse effects on the heart?
Which short-acting beta2-agonist was taken off the market in many countries due to its adverse effects on the heart?
- Ipratropium bromide
- Terbutaline
- Salbutamol
- Fenoterol (correct)
Which class of medication is recommended for all stages of COPD?
Which class of medication is recommended for all stages of COPD?
- Short-acting beta2-agonists (correct)
- Anticholinergics
- Methylxanthines
- Long-acting beta2-agonists
Which bronchodilator has shown some benefit in bronchodilation and dyspnea for stable COPD patients but has limited use for COPD?
Which bronchodilator has shown some benefit in bronchodilation and dyspnea for stable COPD patients but has limited use for COPD?
Which short-acting beta2-agonist provides effective relief of symptoms and prevention of exercise-induced bronchospasm?
Which short-acting beta2-agonist provides effective relief of symptoms and prevention of exercise-induced bronchospasm?
Which bronchodilator resulted in similar improvements in lung function and health status compared to albuterol in a study comparing the two medications?
Which bronchodilator resulted in similar improvements in lung function and health status compared to albuterol in a study comparing the two medications?
What is the most commonly used SABA in the USA?
What is the most commonly used SABA in the USA?
Which SABA shows the most potent effect on peripheral muscles due to its non-selectivity for beta receptors?
Which SABA shows the most potent effect on peripheral muscles due to its non-selectivity for beta receptors?
What effect do SABAs have on lung function decline?
What effect do SABAs have on lung function decline?
Which LABA showed significant bronchoprotective properties against challenges like methacholine and adenosine monophosphate?
Which LABA showed significant bronchoprotective properties against challenges like methacholine and adenosine monophosphate?
What is considered the minimal clinically important difference in FEV1 required to relieve symptoms and escalate to recovery?
What is considered the minimal clinically important difference in FEV1 required to relieve symptoms and escalate to recovery?
Which anticholinergic agent has demonstrated superiority over ipratropium in improving lung function and health-related quality of life?
Which anticholinergic agent has demonstrated superiority over ipratropium in improving lung function and health-related quality of life?
What was found to be associated with an increased risk of adverse cardiovascular events in a recent systematic review and meta-analysis?
What was found to be associated with an increased risk of adverse cardiovascular events in a recent systematic review and meta-analysis?
Which type of adverse effects are typically dose-dependent and mild for all SABAs?
Which type of adverse effects are typically dose-dependent and mild for all SABAs?
What have studies shown regarding the benefits of LABAs used in patients with stable COPD compared to a placebo?
What have studies shown regarding the benefits of LABAs used in patients with stable COPD compared to a placebo?
Which respiratory challenge showed significant bronchoprotective properties with arformoterol?
Which respiratory challenge showed significant bronchoprotective properties with arformoterol?
Why did the FDA approve the use of tiotropium and salmeterol in combination for COPD patients?
Why did the FDA approve the use of tiotropium and salmeterol in combination for COPD patients?
Why is combination therapy less well defined in COPD compared to asthma?
Why is combination therapy less well defined in COPD compared to asthma?
What was the rationale behind including a trial of dual bronchodilator therapy in the GOLD guidelines?
What was the rationale behind including a trial of dual bronchodilator therapy in the GOLD guidelines?
Why was there a previous assumption that only anticholinergics should be used in COPD management?
Why was there a previous assumption that only anticholinergics should be used in COPD management?
Why might the anti-inflammatory effects of corticosteroids in combination inhalers confound the interpretation of bronchodilator monotherapy in COPD?
Why might the anti-inflammatory effects of corticosteroids in combination inhalers confound the interpretation of bronchodilator monotherapy in COPD?
What makes combination therapy relevant for some COPD patients?
What makes combination therapy relevant for some COPD patients?
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