Chapter 37 Pharm
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Questions and Answers

What is the main similarity between Emphysema, Chronic Bronchitis, and Asthma in the context of COPD?

  • None of them are fully reversible. (correct)
  • Emphysema is fully reversible while Chronic Bronchitis and Asthma are not.
  • Chronic Bronchitis is fully reversible while Emphysema and Asthma are not.
  • Asthma is fully reversible while Emphysema and Chronic Bronchitis are not.
  • Which type of Non selective adrenergic bronchodilator stimulates both alphas and betas?

  • Salmeterol
  • Epi (correct)
  • Albuterol
  • Metaproterenol
  • What is the MOA of Beta-Adrenergic Agonists?

  • Secretion of mucus in the airway
  • No effect on the airway
  • Dilation of the airway (correct)
  • Constriction of the airway
  • Which medication is known to help reduce secretions in COPD patients?

    <p>Ipratropium</p> Signup and view all the answers

    What is the main adverse effect of anticholinergics in COPD patients?

    <p>Dry mouth</p> Signup and view all the answers

    What is the primary indication for Corticosteroids in chronic asthma treatment?

    <p>Reduction of inflammation</p> Signup and view all the answers

    What is the primary purpose of LABAs in the treatment of COPD?

    <p>Preventing bronchospasms</p> Signup and view all the answers

    Which adverse effect is NOT commonly associated with Beta-Adrenergic agonists in COPD treatment?

    <p>Ototoxicity</p> Signup and view all the answers

    When educating patients taking Theophylline, what item should we most stress to them they need to avoid?

    <p>Caffeine</p> Signup and view all the answers

    What is the mechanism of action of anticholinergics in treating COPD?

    <p>Binding to Ach receptors causing airway dilation</p> Signup and view all the answers

    When can corticosteroids be given in the treatment of acute asthma?

    <p>Intravenously</p> Signup and view all the answers

    What should patients do to reduce the risk of oral fungal infections when taking corticosteroids?

    <p>Gargle and rinse mouth</p> Signup and view all the answers

    Which statement about education for patients taking corticosteroids is TRUE?

    <p>Patients should use a spacer for successful inhalations.</p> Signup and view all the answers

    Which inhaler ingredient combination is found in Advair?

    <p><strong>Fluticasone</strong> and salmeterol</p> Signup and view all the answers

    What is a common adverse effect of corticosteroids that can occur if not cleaned properly or with bad hygiene?

    <p>Oral fungal infections</p> Signup and view all the answers

    Which medication is indicated for mild to moderate cases of asthma?

    <p>Theophylline</p> Signup and view all the answers

    What is the main reason to educate patients taking corticosteroids about keeping their equipment clean and knowing the number of doses?

    <p>To avoid oral fungal infections</p> Signup and view all the answers

    Which beta-adrenergic bronchodilator stimulates both Beta2 and Beta1 receptors?

    <p>Metaproterenol</p> Signup and view all the answers

    What is the primary indication for the use of beta-adrenergic agonists in respiratory conditions?

    <p>Relieving bronchospasms</p> Signup and view all the answers

    What mediation is a Selective Beta2 – Stimulates only Beta2’s?

    <p>Albuterol</p> Signup and view all the answers

    COPD, a disease of the ____ respiratory tract

    <p>Lower</p> Signup and view all the answers

    COPD is an umbrella term for __________

    <p>All of the Answers are correct</p> Signup and view all the answers

    This SABA inhaler is used the most commonly

    <p>Albuterol</p> Signup and view all the answers

    Match

    <p>SABA inhaler = Levalbuterol LABA inhaler = Arformoterol Bronchodilator = Vilanterol Anticholinergic = Aclidinium</p> Signup and view all the answers

    Match

    <p>Anticholinergic = Tiotropium Corticosteroid = Beclomethasone SABA inhaler = Terbutaline LABA inhaler = Formoterol</p> Signup and view all the answers

    Match

    <p>Corticosteroid = Budesonide SABA inhaler = Metaproterenol Xanthine = Theophylline LABA = Salmeterol</p> Signup and view all the answers

    Match

    <p>Nonselective adrenergic = Epinepherine Selective Beta2 = Albuterol Corticosteroid = Ciclesonide Nonselective Beta-adrenergic = Metaproterenol</p> Signup and view all the answers

    <p>Corticosteroid inhaler = Flovent Corticosteroid = Mometasone Corticosteroid intranasal = Flonase Anticholinergic that is dosed twice daily = Ipratropium</p> Signup and view all the answers

    A prolonged asthma attack that does not respond to typical drug therapy.

    <p>Status Asthmaticas</p> Signup and view all the answers

    Study Notes

    Similarities and Conditions

    • Emphysema, Chronic Bronchitis, and Asthma are all forms of Chronic Obstructive Pulmonary Disease (COPD), characterized by air flow obstruction and difficulty breathing.
    • COPD is an umbrella term that encompasses various respiratory conditions including emphysema and chronic bronchitis.

    Adrenergic Bronchodilators

    • Non-selective adrenergic bronchodilators stimulate both alpha and beta receptors.
    • Beta-Adrenergic Agonists promote bronchodilation by relaxing bronchial smooth muscle through the activation of beta receptors.

    Treatments and Medications

    • Anticholinergics are primarily used to reduce secretions in COPD patients.
    • Main adverse effect of anticholinergics in COPD patients is dry mouth and throat irritation.
    • Corticosteroids are indicated for chronic asthma treatment to reduce inflammation.
    • Long-acting beta agonists (LABAs) are used primarily to provide sustained bronchodilation in COPD management.

    Adverse Effects and Education

    • A common adverse effect NOT associated with Beta-Adrenergic agonists is respiratory depression.
    • When using Theophylline, patients should avoid caffeine to prevent adverse effects.
    • Anticholinergics work by blocking acetylcholine receptors, leading to bronchodilation.

    Corticosteroids and Patient Management

    • Corticosteroids can be administered during an acute asthma episode to quickly reduce inflammation.
    • Patients should rinse their mouths after corticosteroid use to minimize the risk of oral fungal infections.
    • Teaching patients about maintaining clean inhalers is crucial to prevent contamination and ensure effective dosing.

    Inhaler Ingredients and Medications

    • Advair contains a combination of fluticasone (a corticosteroid) and salmeterol (a LABA).
    • Poor hygiene with corticosteroids can lead to oral candidiasis (thrush).
    • Mild to moderate asthma cases are often treated with Short-acting Beta Agonists (SABAs).
    • Patients must keep track of device doses to prevent the risk of overuse and ensure medication efficacy.

    Miscellaneous

    • A prolonged asthma attack that does not respond to typical drug therapy is termed status asthmaticus.
    • The most commonly used SABA inhaler is albuterol.
    • A beta-adrenergic bronchodilator that stimulates both Beta2 and Beta1 receptors is isoproterenol.
    • The primary indication for beta-adrenergic agonists is to relieve acute bronchospasm.

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