Breast Cancer Overview and Treatment
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Questions and Answers

What is the most common type of breast cancer?

  • Ductal carcinoma in situ
  • Phyllodes tumor
  • Adenocarcinoma (correct)
  • Lobular carcinoma
  • What genetic mutations significantly increase the risk of breast cancer?

  • APC and XRCC2
  • TP53 and PTEN
  • HER2 and MMR
  • BRCA1 and BRCA2 (correct)
  • Which of the following factors is NOT a risk factor for breast cancer?

  • Obesity
  • Family history
  • Early menarche
  • Frequent exercise (correct)
  • What are the two types of post-mastectomy breast reconstruction?

    <p>Prosthetic implant-based and autologous tissue-based</p> Signup and view all the answers

    Which factor would NOT influence the choice of reconstruction technique?

    <p>Patient's history of hypertension</p> Signup and view all the answers

    What is a key advantage of skin-sparing techniques in breast reconstruction?

    <p>Improved symmetry after reconstruction</p> Signup and view all the answers

    What is the primary purpose of placing a tissue expander in a two-stage reconstruction?

    <p>To minimize tension on the mastectomy flap until desired volume is achieved</p> Signup and view all the answers

    What is a potential limitation when using latissimus dorsi myo-cutaneous flap in breast reconstruction?

    <p>The availability of sufficient donor tissue</p> Signup and view all the answers

    During the second-stage procedure of a two-stage reconstruction, what is commonly performed to enhance breast aesthetics?

    <p>Capsulotomy to increase breast projection and ptosis</p> Signup and view all the answers

    What does the duration of implant-based breast reconstructive surgery typically range from?

    <p>2 to 9 hours</p> Signup and view all the answers

    What is the primary benefit of using autologous tissue for breast reconstruction?

    <p>More natural appearance and consistency</p> Signup and view all the answers

    Which procedure allows for the largest amount of tissue transfer in breast reconstruction?

    <p>Free TRAM flap</p> Signup and view all the answers

    What is a significant disadvantage of autologous tissue reconstruction?

    <p>More complex surgical procedure</p> Signup and view all the answers

    Which of the following factors would likely increase the risk of TRAM flap failure?

    <p>Smoking</p> Signup and view all the answers

    What technique does the DIEP flap utilize to enhance perfusion and minimize donor site morbidities?

    <p>Dissecting tissue while preserving muscle</p> Signup and view all the answers

    What is the typical duration range for a TRAM flap surgery?

    <p>5 to 12 hours</p> Signup and view all the answers

    Which statement about the pedicle TRAM flap is accurate?

    <p>It maintains blood supply via the superior epigastric artery.</p> Signup and view all the answers

    Which comorbidity is NOT associated with increased mortality from breast cancer?

    <p>Hyperlipidemia</p> Signup and view all the answers

    What is a primary reason that complicates anesthetic management in obese patients undergoing breast surgery?

    <p>Decreased airway compliance</p> Signup and view all the answers

    Which statement accurately reflects the effects of obesity on the cardiovascular system?

    <p>Hypertension with obesity can result in concentric hypertrophy.</p> Signup and view all the answers

    How does obesity impact the respiratory system in patients undergoing anesthesia?

    <p>Airway closure can lead to arterial hypoxemia.</p> Signup and view all the answers

    What impact does advanced age have on breast cancer incidence?

    <p>Increases the risk, especially in women over 65.</p> Signup and view all the answers

    Which of the following is NOT a negative consequence of obesity on anesthetic management?

    <p>Increased pulmonary compliance.</p> Signup and view all the answers

    What endocrine-related issue is more likely to occur in obese patients?

    <p>Altered glucose metabolism</p> Signup and view all the answers

    What is a potential outcome of small doses of Adriamycin in patients undergoing surgery?

    <p>Acute myocardial dysfunction</p> Signup and view all the answers

    Which anesthetic consideration is crucial for patients treated with Adriamycin?

    <p>Comprehensive preoperative cardiac evaluation</p> Signup and view all the answers

    What is a major concern associated with the use of Adriamycin during anesthesia?

    <p>Decreased myocardial performance</p> Signup and view all the answers

    For patients with bilateral mastectomies, what alternative site should be considered for IV placement?

    <p>Lower extremity</p> Signup and view all the answers

    What is the estimated frequency of significant cardiomyopathy in patients receiving less than 450 mg/m² of Adriamycin?

    <p>1% to 10%</p> Signup and view all the answers

    Which of the following statements about the anesthetic management for patients treated with chemotherapeutic agents is true?

    <p>Cardiac function should be monitored due to potential drug interactions.</p> Signup and view all the answers

    What physiological effect does hypothermia have on flap reconstruction during surgery?

    <p>Causes vasoconstriction and restricts blood supply</p> Signup and view all the answers

    Which of the following is a potential risk associated with the use of dextran during flap reconstruction?

    <p>Decreased hemostasis</p> Signup and view all the answers

    In what position should a patient typically be placed to harvest the latissimus dorsi flap?

    <p>Lateral decubitus</p> Signup and view all the answers

    What should be prioritized to prevent complications when the patient is moved to a sitting position during surgery?

    <p>Keeping the endotracheal tube secure</p> Signup and view all the answers

    How can the emergence from anesthesia be impacted by hypothermia post-surgery?

    <p>Decreased hepatic drug metabolism</p> Signup and view all the answers

    What complication may arise from abrupt positioning changes during breast reconstructive surgery?

    <p>Increased risk of nerve injury</p> Signup and view all the answers

    What is the primary reason to maintain mean arterial pressure within 20% of preoperative values during TRAM flap procedures?

    <p>To ensure adequate perfusion pressure to the flap tissue</p> Signup and view all the answers

    Which factor is most relevant when determining the need for blood or plasma transfusions during reconstructive breast surgery?

    <p>The patient's preoperative physical status and hemodynamic stability</p> Signup and view all the answers

    What is a significant potential complication associated with autologous blood donation prior to surgery?

    <p>Higher rates of postoperative transfusion due to preoperative anemia</p> Signup and view all the answers

    Why is the use of nitrous oxide discouraged during TRAM flap reconstruction?

    <p>It can lead to abdominal distention and compromise cosmetic results</p> Signup and view all the answers

    What is a significant drawback of administering large volumes of crystalloid fluids during surgery?

    <p>It may increase the risk of fluid overload</p> Signup and view all the answers

    What impact does hypertension have during the TRAM flap procedure?

    <p>It frequently causes excessive bleeding</p> Signup and view all the answers

    When considering hemostatic factors during surgery, which laboratory values need to be monitored most closely?

    <p>Serial hemoglobin values and coagulation profiles</p> Signup and view all the answers

    What is the most significant advantage of using a thoracic paravertebral nerve block in the postoperative period?

    <p>Promotes deep breathing to prevent atelectasis</p> Signup and view all the answers

    What common reason necessitates the reintervention of breast implants over the years?

    <p>Development of contractures, migration, leakage, or rupture.</p> Signup and view all the answers

    During the postoperative period, which of the following practices is crucial to prevent atelectasis?

    <p>Encouraging deep breathing exercises to inhibit sympathetic hyperactivity</p> Signup and view all the answers

    What is a major consideration when managing postoperative pain, particularly regarding narcotic administration?

    <p>Continuous monitoring is essential to prevent respiratory depression.</p> Signup and view all the answers

    Study Notes

    Breast Cancer Overview

    • Over 211,000 women and 1700 men are diagnosed with breast cancer annually.
    • Adenocarcinoma is the most common type.
    • Cellular dysplasia starts in breast duct and lobule cells.
    • Risk factors include family history, nulliparity, early menarche, advanced age, obesity, and personal breast cancer history.
    • BRCA1/2 mutations increase breast cancer risk by 40-85%.
    • Some with these mutations have prophylactic mastectomies.

    Breast Cancer Treatment

    • Often treated with surgery, radiation, chemotherapy, and hormone therapy.
    • Breast reconstruction is possible, either immediately or later.

    Post-Mastectomy Reconstruction Types

    • Prosthetic implant-based reconstruction.
    • Autologous tissue-based reconstruction.

    Factors Influencing Reconstruction Choice

    • Cancer type and location.
    • Resection extent.
    • Patient medical/surgical risk.
    • Desired breast size/shape.
    • Patient preference.

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    Description

    This quiz covers essential information about breast cancer, including statistics, types, risk factors, and treatment options. It also explores the different types of post-mastectomy reconstruction and the factors influencing the choice of reconstruction methods. Test your knowledge on breast cancer and its management.

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