10-L1

Play an AI-generated podcast conversation about this lesson

What is a consequence of a lack of leptin production or insensitivity to leptin?

Increased production of ATP

Reduced appetite

Obesity (correct)

Improved insulin sensitivity

What is the effect of leptin on mitochondria?

It has no effect on mitochondria

It induces the expression of uncoupling proteins (correct)

It decreases the production of heat

It increases the production of ATP

What is the role of insulin in appetite regulation?

It has no effect on appetite

It stimulates appetite

It only regulates long-term appetite

It suppresses appetite (correct)

What is amylin secreted with?

Insulin Signup and view all the answers

What is pramlintide?

An analogue of amylin Signup and view all the answers

What do neurons in the arcuate nucleus sense?

Both glucose and fatty acid levels in the blood Signup and view all the answers

What is the role of leptin in appetite regulation?

It suppresses appetite Signup and view all the answers

What is associated with obesity and often leads to type 2 diabetes?

Insulin resistance Signup and view all the answers

What is the role of POMC in the brain?

Suppresses appetite Signup and view all the answers

What is the function of the reward system in the brain?

Involved in the control of feeding Signup and view all the answers

What happens to ghrelin release when the stomach is full?

Ghrelin release decreases Signup and view all the answers

What is the function of PYY?

Suppresses appetite Signup and view all the answers

What is the function of leptin?

Suppresses appetite Signup and view all the answers

What is the source of leptin in the body?

Adipocytes in fat stores Signup and view all the answers

What is the relationship between leptin levels and adipose tissue?

Leptin levels increase with increased adipose tissue Signup and view all the answers

What is the effect of leptin on neurons in the arcuate nucleus?

Leptin inhibits stimulatory neurons Signup and view all the answers

According to the World Health Organization's estimate, how many people are overweight?

Over 1 billion Signup and view all the answers

What percentage of obese adults experience morbidity arising from their obesity?

80% Signup and view all the answers

What is thought to be a partial cause of obesity?

All of the above Signup and view all the answers

What is the estimated genetic component of obesity?

60-84% Signup and view all the answers

What concept suggests that individuals are genetically predisposed to store energy efficiently?

Thrifty phenotype Signup and view all the answers

What is metabolic syndrome characterized by?

A group of symptoms including insulin resistance, dyslipidaemia, glucose intolerance and hypertension associated with central adiposity Signup and view all the answers

What is thought to contribute to the rise of chronic obesity in the developed world?

Constant supply of food Signup and view all the answers

What is the primary reason for the development of metabolic syndrome?

Observation of a common pattern of symptoms in obese people Signup and view all the answers

Where is the appetite centre located in the brain?

Arcuate nucleus Signup and view all the answers

What is the role of excitatory neurons in the appetite centre?

Stimulate appetite Signup and view all the answers

What is the function of primary neurons in the appetite centre?

Sense metabolite levels and respond to hormones Signup and view all the answers

What is the role of inhibitory neurons in the appetite centre?

Suppress appetite Signup and view all the answers

What is the result of the release of neuropeptide Y (NPY) and agouti-related peptide (AgRP)?

Appetite stimulation Signup and view all the answers

What is the function of the vagus nerve in the appetite centre?

Co-ordinate a response Signup and view all the answers

What is pro-opiomelanocortin (POMC)?

A polypeptide prohormone Signup and view all the answers

What is the result of the release of pro-opiomelanocortin (POMC)?

Appetite suppression Signup and view all the answers

What is the risk of type 2 diabetes increased by in individuals with metabolic syndrome?

5-fold Signup and view all the answers

What is the prevalence of metabolic syndrome increasing due to?

Increasing obesity Signup and view all the answers

Where is fat storage associated with metabolic syndrome?

Around the abdomen Signup and view all the answers

What is the impact of metabolic syndrome on the prevalence of cardiovascular disease and type 2 diabetes?

Marked impact Signup and view all the answers

Which ethnic group has a higher predisposition to central obesity?

South Asians Signup and view all the answers

What is central fat accumulation strongly associated with?

Insulin resistance Signup and view all the answers

Why is BMI not an ideal measurement of central fat?

It does not account for muscle mass Signup and view all the answers

What is the relationship between obesity and type 2 diabetes in children?

Obesity is an important cause of type 2 diabetes in children Signup and view all the answers

What is the risk of heart disease increased by in individuals with metabolic syndrome?

3-fold Signup and view all the answers

What is a characteristic of metabolic syndrome?

High blood glucose Signup and view all the answers

10-L1

Choose a study mode

Podcast

Questions and Answers

What is a consequence of a lack of leptin production or insensitivity to leptin?

What is the effect of leptin on mitochondria?

What is the role of insulin in appetite regulation?

What is amylin secreted with?

What is pramlintide?

What do neurons in the arcuate nucleus sense?

What is the role of leptin in appetite regulation?

What is associated with obesity and often leads to type 2 diabetes?

What is the role of POMC in the brain?

What is the function of the reward system in the brain?

What happens to ghrelin release when the stomach is full?

What is the function of PYY?

What is the function of leptin?

What is the source of leptin in the body?

What is the relationship between leptin levels and adipose tissue?

What is the effect of leptin on neurons in the arcuate nucleus?

According to the World Health Organization's estimate, how many people are overweight?

What percentage of obese adults experience morbidity arising from their obesity?

What is thought to be a partial cause of obesity?

What is the estimated genetic component of obesity?

What concept suggests that individuals are genetically predisposed to store energy efficiently?

What is metabolic syndrome characterized by?

What is thought to contribute to the rise of chronic obesity in the developed world?

What is the primary reason for the development of metabolic syndrome?

Where is the appetite centre located in the brain?

What is the role of excitatory neurons in the appetite centre?

What is the function of primary neurons in the appetite centre?

What is the role of inhibitory neurons in the appetite centre?

What is the result of the release of neuropeptide Y (NPY) and agouti-related peptide (AgRP)?

What is the function of the vagus nerve in the appetite centre?

What is pro-opiomelanocortin (POMC)?

What is the result of the release of pro-opiomelanocortin (POMC)?

What is the risk of type 2 diabetes increased by in individuals with metabolic syndrome?

What is the prevalence of metabolic syndrome increasing due to?

Where is fat storage associated with metabolic syndrome?

What is the impact of metabolic syndrome on the prevalence of cardiovascular disease and type 2 diabetes?

Which ethnic group has a higher predisposition to central obesity?

What is central fat accumulation strongly associated with?

Why is BMI not an ideal measurement of central fat?

What is the relationship between obesity and type 2 diabetes in children?

What is the risk of heart disease increased by in individuals with metabolic syndrome?

What is a characteristic of metabolic syndrome?

More Like This

Neuroscience Quiz: Opiates and Ecstasy

Neuroscience Chapter 12 Flashcards

Neuroscience: Types of Neurons

Neuroscience: Circumventricular Organs