Podcast
Questions and Answers
Which artery provides blood supply to the choroid plexus and the optic chiasma?
Which artery provides blood supply to the choroid plexus and the optic chiasma?
What is the role of the anterior communicating artery in the Circle of Willis?
What is the role of the anterior communicating artery in the Circle of Willis?
Which of the following arteries is NOT a terminal branch of the internal carotid artery?
Which of the following arteries is NOT a terminal branch of the internal carotid artery?
Which structure does the internal carotid artery primarily supply?
Which structure does the internal carotid artery primarily supply?
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What is the significance of the posterior communicating artery in the cerebral arterial circle?
What is the significance of the posterior communicating artery in the cerebral arterial circle?
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Which areas are primarily supplied by the anterior cerebral artery?
Which areas are primarily supplied by the anterior cerebral artery?
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What is the primary function of the areas supplied by the middle cerebral artery?
What is the primary function of the areas supplied by the middle cerebral artery?
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Which statement accurately describes the posterior cerebral artery?
Which statement accurately describes the posterior cerebral artery?
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Which regions are NOT supplied by the middle cerebral artery?
Which regions are NOT supplied by the middle cerebral artery?
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Which arteries branch from the anterior cerebral artery to supply important brain structures?
Which arteries branch from the anterior cerebral artery to supply important brain structures?
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What area of the brain is primarily supplied by the vertebro-basilar arteries?
What area of the brain is primarily supplied by the vertebro-basilar arteries?
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What is the primary role of the Circle of Willis?
What is the primary role of the Circle of Willis?
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What causes an ischaemic stroke?
What causes an ischaemic stroke?
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Which arteries contribute to the anterior spinal artery?
Which arteries contribute to the anterior spinal artery?
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What is the correct path of the internal carotid arteries as they enter the skull?
What is the correct path of the internal carotid arteries as they enter the skull?
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Which of the following arteries is NOT part of the posterior system supplying the brain?
Which of the following arteries is NOT part of the posterior system supplying the brain?
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Which vessels supply the areas of the spinal cord?
Which vessels supply the areas of the spinal cord?
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From which artery do the two vertebral arteries originate?
From which artery do the two vertebral arteries originate?
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Which area is primarily supplied by the medial striate arteries?
Which area is primarily supplied by the medial striate arteries?
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What type of attack is characterized by temporary neurological symptoms due to ischaemia?
What type of attack is characterized by temporary neurological symptoms due to ischaemia?
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Which type of stroke refers to a sudden focal neurological deficit due to impaired cerebral blood flow?
Which type of stroke refers to a sudden focal neurological deficit due to impaired cerebral blood flow?
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The lateral striate arteries originate from which cerebral arteries?
The lateral striate arteries originate from which cerebral arteries?
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Which is a common cause of ischaemic stroke?
Which is a common cause of ischaemic stroke?
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What indicates contralateral impaired sensations of position and movement in the context of corticospinal tracts?
What indicates contralateral impaired sensations of position and movement in the context of corticospinal tracts?
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Which cranial nerve nucleus is related to ipsilateral paralysis of the tongue?
Which cranial nerve nucleus is related to ipsilateral paralysis of the tongue?
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Which of the following veins are part of the superficial cerebral veins?
Which of the following veins are part of the superficial cerebral veins?
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What is the pathway for venous drainage of the brain?
What is the pathway for venous drainage of the brain?
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What is a characteristic feature of the venous drainage of the spinal cord?
What is a characteristic feature of the venous drainage of the spinal cord?
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What is the primary cause of cell death in a stroke?
What is the primary cause of cell death in a stroke?
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Which type of stroke is primarily due to the rupture of a blood vessel?
Which type of stroke is primarily due to the rupture of a blood vessel?
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What is a common symptom associated with occlusion of the middle cerebral artery?
What is a common symptom associated with occlusion of the middle cerebral artery?
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How does a PICA syndrome manifest concerning sensory loss?
How does a PICA syndrome manifest concerning sensory loss?
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What symptom is NOT typically associated with medial medullary syndrome?
What symptom is NOT typically associated with medial medullary syndrome?
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What is a major consequence of thrombosis affecting cerebral arteries?
What is a major consequence of thrombosis affecting cerebral arteries?
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Which physiological impact does an embolism have when generated in a blood vessel outside of the brain?
Which physiological impact does an embolism have when generated in a blood vessel outside of the brain?
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What defining feature characterizes cerebellar symptoms in stroke?
What defining feature characterizes cerebellar symptoms in stroke?
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Study Notes
Course Information
- Class: Year 2 Semester 1
- Course: Medicine
- Lecturer: Dr. Vijayalakshmi S B
- Date: 06/11/2024
- Topic: Brain blood vessels and intracerebral bleeds
Learning Outcomes
- Describe the blood supply to the brain and spinal cord
- Identify the areas supplied by individual arteries
- Describe the Circle of Willis
- Define "stroke" and differentiate between ischaemic and hemorrhagic stroke causes
- Explain the effect of focal lesions caused by strokes in major cortical functional areas
Blood Supply to the Brain
- Anterior system: Internal carotid arteries supply most of the forebrain, except the occipital lobe.
- Posterior system: Vertebro-basilar arteries supply the spinal cord, brainstem, cerebellum, and occipital lobes.
- Connecting system: The two systems are connected via the Circle of Willis.
Blood Supply
- Internal carotid arteries
- Vertebral arteries
Vertebrobasilar System
- Two vertebral arteries arise from the subclavian artery.
- Ascend in transverse foramina.
- Enter foramen magnum.
- Release posterior inferior cerebellar artery (PICA)
- Release posterior and anterior spinal arteries.
- Merge into a single basilar artery.
Vertebral Arteries and Spinal Cord
- Anterior spinal arteries unite to form a single anterior spinal artery.
- Two posterior spinal arteries travel vertically.
- Spinal arteries are supplemented by radicular arteries entering intervertebral foramina arising from segmental arteries.
- Artery of Adamkiewicz is located in the lower thoracic or upper lumbar region.
Branches of the Basilar Artery
- Formed at the ponto-medullary junction.
- Anterior Inferior Cerebellar Arteries (AICA)
- Labyrinthine arteries
- Pontine arteries
- Superior cerebellar arteries
- Posterior cerebral arteries
- Communicate to internal carotid artery (ICA) via posterior communicating arteries (PCA)
Pontomedullary Junction
- Location of the basilar artery formation.
- Contains various arteries.
Internal Carotid Artery
- Cervical part of the ICA enters the carotid foramen/canal.
- Passes through the carotid canal as the petrous part of the ICA.
- Opens into the top part of the foramen lacerum and travels through the cavernous sinus (cavernous part).
- Cerebral part of the ICA joins the Circle of Willis.
Branches of the Internal Carotid Artery
- Ophthalmic
- Through the optic canal to the eye.
- Anterior choroidal artery
- To choroid plexus, enters the inferior tip of the lateral ventricle.
- Also supplies optic chiasma, optic tract, lateral geniculate body (thalamus), and part of the internal capsule.
- A branch to the pituitary gland.
- Posterior communicating artery
- Two terminal branches
- Leading to communicating arteries and middle cerebral arteries.
Anterior Cerebral Artery
- Supplies the orbital surface of the frontal lobe, medial aspect of hemisphere (except occipital lobe), upper border of frontal and parietal lobes.
- Supplies the lower limb.
- Supplies perineum, micturition, and defecation functions.
- Medial striate arteries supply basal ganglia and the anterior limb and genu of the internal capsule.
Middle Cerebral Artery
- Supplies the lateral fissure and lateral aspect of the hemisphere (except anterior cerebral strip and occipital lobe).
- Supplies the lateral aspects of the frontal, parietal, and temporal lobes.
- Medially supplies the anterior temporal lobe.
- Supplies speech areas (Broca's and Wernicke's areas) and auditory areas.
- Lateral striatal or lenticulostriate arteries supply basal ganglia and internal capsule.
Posterior Cerebral Artery
- Supplies the occipital lobe and infero-medial temporal lobe.
- Usually a terminal branch of the basilar artery.
- Rarely, may receive blood supply via posterior communicating artery.
Blood Supply of Central Cerebral Areas
- Basal ganglia, internal capsule.
- Anterior choroidal and striate arteries.
Internal Capsule
- Anterior limb - frontopontine fibers, thalamus to prefrontal.
- Genu - corticobulbar fibers.
- Posterior limb - corticospinal and sensory fibers, corticobulbar fibers.
- Retrolentiform - fibers to auditory and visual cortex.
Striate Arteries
- Various names (lenticulostriate, thalamostriate, long central artery).
- Medial striate arteries: anterior cerebral artery, internal capsule, nearby basal ganglia, and parts of the hypothalamus.
- Lateral striate arteries: middle cerebral artery and anterior choroidal arteries, nearby basal ganglia, and putamen.
- Central branches of posterior cerebral arteries including branches from posterior communicating arteries and supply thalamus and third ventricle.
Stroke
- Sudden development of focal neurological deficits due to impaired cerebral blood flow.
- Types: ischaemic and hemorrhagic.
- Common causes: spontaneous cerebrovascular accidents (CVA), cerebral thrombosis, cerebral hemorrhage, cerebral embolism, subarachnoid haemorrhage.
- Transient Ischaemic Attacks (TIAs): neurologic symptoms due to ischemia (e.g., carotid or vertebrobasilar stenosis). Symptoms last a few minutes (but can be up to an hour), with symptoms like staggering, dizziness, light-headedness, fainting, and paraesthesia. TIAs are a risk factor for stroke.
FAST
- Face: Has the face fallen on one side? Can they smile?
- Arms: Can they raise both arms and keep them there?
- Speech: Is their speech slurred?
- Time: Time to call 999 immediately if you see any of these signs.
Stroke Symptoms
- Cerebral hemispheres: contralateral symptoms.
- Anterior cerebral: contralateral hemiplegia and anaesthesia
- Middle cerebral: contralateral hemiplegia and anaesthesia, possible aphasia
- Posterior cerebral: contralateral hemianopia
- Vertebrobasilar: mix of contralateral and ipsilateral symptoms
- Brainstem: varies depending on the specific area affected.
- Cerebellar hemispheres: ipsilateral symptoms, with cerebellar signs (balance and coordination problems), including involvement of superior cerebellar, AICA and PICA.
Middle Cerebral Artery (MCA) Stroke
- Contralateral motor and sensory loss (sparing lower limb and perineum).
- Possible speech deficits if the dominant hemisphere is involved.
- Supplies lateral striatal or lenticulostriate arteries to basal ganglia and the internal capsule.
PICA Syndrome (Lateral Medullary Syndrome)
- Lateral medulla is supplied by the PICA.
- Symptoms: ipsilateral pain and temperature loss from the face, vertigo, nystagmus, tinnitus, ipsilateral Horner's syndrome (ptosis, meiosis, anhydrosis), contralateral pain and temperature loss in the body, loss of taste from ipsilateral tongue, hoarseness/dysphagia, and involvement of cranial nerves.
Medial Medullary Syndrome
- Medial part of the medulla is supplied by the vertebral artery.
- Symptoms: contralateral hemiparesis, impaired position and tactile discrimination, ipsilateral tongue paralysis (involving hypoglossal nerve and nucleus).
Subarachnoid Hemorrhage
- High-density blood in the subarachnoid space.
Venous Drainage of the Brain
- Drained by a system of veins that empty into dural sinuses.
- Sinuses drain into the right and left internal jugular veins.
- Cerebral veins are divided into superficial and deep cerebral veins.
- Superficial: superficial middle cerebral vein, superior anastomotic vein of Trolard, inferior anastomotic vein of Labbé
- Deep: great cerebral vein of Galen, basal vein of Rosenthal, internal cerebral vein
Venous Drainage of the Spinal Cord
- Posterior lateral spinal veins, posterior median spinal vein, anterior median spinal vein, anterior lateral spinal veins.
- Drainage of veins from the spinal cord to the venous system.
Video Links (for further learning)
- Provide links to videos about specific stroke types.
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Description
This quiz focuses on the anatomy of brain blood vessels, specifically the blood supply to the brain and spinal cord. It covers key topics such as the Circle of Willis, types of strokes, and the impact of focal lesions. Test your understanding of these critical vascular concepts in medicine.