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Questions and Answers
Which of the following is NOT a characteristic of a nutraceutical?
Which of the following is NOT a characteristic of a nutraceutical?
Which of these is an example of an organised vegetable crude drug?
Which of these is an example of an organised vegetable crude drug?
Which of the following is NOT a source of crude drugs?
Which of the following is NOT a source of crude drugs?
What is the main focus of pharmacognosy?
What is the main focus of pharmacognosy?
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What is a key difference between organised and unorganised vegetable crude drugs?
What is a key difference between organised and unorganised vegetable crude drugs?
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Which of the following are traditional medicine systems that utilize natural drugs?
Which of the following are traditional medicine systems that utilize natural drugs?
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Which of the following is an example of a food that contains carotenoids?
Which of the following is an example of a food that contains carotenoids?
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What percentage of the world's population is estimated to use traditional herbal medicine for primary healthcare?
What percentage of the world's population is estimated to use traditional herbal medicine for primary healthcare?
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What is the primary reason for studying pharmacognosy?
What is the primary reason for studying pharmacognosy?
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Which of the following topics is NOT covered in the introduction to pharmacognosy?
Which of the following topics is NOT covered in the introduction to pharmacognosy?
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What is the significance of understanding the historical development of plants in pharmacy and medicine?
What is the significance of understanding the historical development of plants in pharmacy and medicine?
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Which of the following is NOT a learning outcome of a basic pharmacognosy course?
Which of the following is NOT a learning outcome of a basic pharmacognosy course?
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What is the primary reason for studying adulteration and evaluation of crude drugs?
What is the primary reason for studying adulteration and evaluation of crude drugs?
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Which of the following is the oldest documented record of plant use for medicinal purposes?
Which of the following is the oldest documented record of plant use for medicinal purposes?
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What is the name of the plant species containing ephedrine?
What is the name of the plant species containing ephedrine?
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What is the significance of the Ebers Papyrus in the history of medicinal plant use?
What is the significance of the Ebers Papyrus in the history of medicinal plant use?
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Who is considered the "father of (Western) medicine"?
Who is considered the "father of (Western) medicine"?
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What is the Corpus Hippocraticum?
What is the Corpus Hippocraticum?
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What is the significance of Claudius Galen's work in the history of medicine?
What is the significance of Claudius Galen's work in the history of medicine?
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What was Pliny the Elder's contribution to the understanding of natural history?
What was Pliny the Elder's contribution to the understanding of natural history?
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How did Taoist thought influence traditional Chinese medicine?
How did Taoist thought influence traditional Chinese medicine?
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Which of the following is NOT a definition of pharmacognosy?
Which of the following is NOT a definition of pharmacognosy?
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What is a key difference between phytotherapy and phytomedicine?
What is a key difference between phytotherapy and phytomedicine?
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Which of the following is NOT a common example of a botanical drug used in herbal remedies?
Which of the following is NOT a common example of a botanical drug used in herbal remedies?
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What is the main focus of phytochemistry?
What is the main focus of phytochemistry?
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What differentiates a natural product from a synthetic compound?
What differentiates a natural product from a synthetic compound?
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What distinguishes a semi-synthetic compound from a pure compound?
What distinguishes a semi-synthetic compound from a pure compound?
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Which of these options is a pure compound, as defined in the text?
Which of these options is a pure compound, as defined in the text?
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What is the primary difference between a synthetic compound and a semi-synthetic compound?
What is the primary difference between a synthetic compound and a semi-synthetic compound?
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Which of these plants is the source of the drug Taxol (Paclitaxel)?
Which of these plants is the source of the drug Taxol (Paclitaxel)?
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What natural product is used in the production of the analgesic, morphine?
What natural product is used in the production of the analgesic, morphine?
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Which of these drugs is used to treat malaria?
Which of these drugs is used to treat malaria?
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What is the name of the natural product used to create the drug, Artemisinin?
What is the name of the natural product used to create the drug, Artemisinin?
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Which of these drugs is derived from a plant species that is NOT specifically identified in the content?
Which of these drugs is derived from a plant species that is NOT specifically identified in the content?
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What is the primary function of the drug Tubocurarine?
What is the primary function of the drug Tubocurarine?
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What is Pharmacognosy?
What is Pharmacognosy?
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What is the main difference between Quinine and Artemisinin?
What is the main difference between Quinine and Artemisinin?
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What is the main focus of the earliest classical Chinese medical texts, as described in the content?
What is the main focus of the earliest classical Chinese medical texts, as described in the content?
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What is the primary difference between the two classical Chinese texts mentioned, 'The work' and 'Ben Cao Gang Mu'?
What is the primary difference between the two classical Chinese texts mentioned, 'The work' and 'Ben Cao Gang Mu'?
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What is a key characteristic of the 'Ben Cao Gang Mu' text?
What is a key characteristic of the 'Ben Cao Gang Mu' text?
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Which of the following is NOT a characteristic of the content provided about traditional medicine?
Which of the following is NOT a characteristic of the content provided about traditional medicine?
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Which of the following is NOT a traditional system of medicine mentioned in the text?
Which of the following is NOT a traditional system of medicine mentioned in the text?
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Which of the following best describes the significance of 'Ayurveda' in the context of the text?
Which of the following best describes the significance of 'Ayurveda' in the context of the text?
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What is the main reason for the continued importance of plants in modern pharmacy and medicine?
What is the main reason for the continued importance of plants in modern pharmacy and medicine?
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What is the main focus of the content regarding the importance of plants in modern pharmacy and medicine?
What is the main focus of the content regarding the importance of plants in modern pharmacy and medicine?
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Flashcards
Nutraceuticals
Nutraceuticals
Substances from food that provide health benefits and prevent disease.
Crude Drugs
Crude Drugs
Vegetable drugs from plant organs without chemical modifications.
Organised Vegetable Crude Drugs
Organised Vegetable Crude Drugs
Therapeutic substances extracted from plant parts like leaves and roots.
Unorganised Vegetable Crude Drugs
Unorganised Vegetable Crude Drugs
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Examples of Nutraceuticals
Examples of Nutraceuticals
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Artemisinin
Artemisinin
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Morphine
Morphine
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Quinine
Quinine
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Aspirin
Aspirin
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Tubocurarine
Tubocurarine
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Taxol
Taxol
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Physostigmine
Physostigmine
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Pharmacognosy
Pharmacognosy
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Phytotherapy
Phytotherapy
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Phytomedicine
Phytomedicine
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Phytochemistry
Phytochemistry
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Natural products
Natural products
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Pure compound
Pure compound
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Synthetic compounds
Synthetic compounds
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Semi-synthetic compounds
Semi-synthetic compounds
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Traditional Chinese Medicine (TCM)
Traditional Chinese Medicine (TCM)
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Ben Cao Gang Mu
Ben Cao Gang Mu
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Ayurveda
Ayurveda
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Four Temperatures
Four Temperatures
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Five Tastes
Five Tastes
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Natural Product Research
Natural Product Research
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Cinchona officinalis
Cinchona officinalis
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Adulteration
Adulteration
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Cytomorphology
Cytomorphology
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Traditional Medicine
Traditional Medicine
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WHO Statistic
WHO Statistic
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Collection & Preparation
Collection & Preparation
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Ebers Papyrus
Ebers Papyrus
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Pedanius Dioscorides
Pedanius Dioscorides
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Corpus Hippocraticum
Corpus Hippocraticum
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Galenical
Galenical
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Shen Nong Ben Cao Jing
Shen Nong Ben Cao Jing
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Pliny the Elder
Pliny the Elder
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Neanderthal medicine
Neanderthal medicine
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Study Notes
B.Pharm PCG 201: Introduction to Pharmacognosy
- Course title: B.Pharm PCG 201: Introduction to Pharmacognosy
- Lecturer: Dr. Ibrahim Malami
- Affiliation: Department of Pharmacognosy & Ethnopharmacy, Faculty of Pharmaceutical Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria.
- Additional Affiliation: Centre For Advanced Medical Research and Training (CAMRET), Usmanu Danfodiyo University, Sokoto, Nigeria.
Highlights
- Topics covered: Introduction to Pharmacognosy, Microscopy, Cytomorphology, Cytology and Cytogenesis, Cell inclusions.
- Hour allocation: Introduction to Pharmacognosy - 10 hours, Microscopy - 13 hours, Cytomorphology - 7 hours
Objectives
- Introduce the scope, significance, and applications of pharmacognosy.
- Highlight important natural products and phytomedicines in medicine and pharmacy.
- Detail different classifications of natural drugs.
- Explain the collection and preparation of natural drugs.
- Explain adulteration and evaluation of crude drugs.
- Provide various publications in pharmacognosy.
Learning Outcomes
- Provide a general scientific overview of pharmacognosy and its key applications.
- Give a historical overview of plant use in pharmacy and medicine.
- Discuss the collection, preparation, and potential adulteration of natural drugs.
- Establish pharmacognosy as a crucial discipline within pharmacy and medicine.
Introduction
- Natural drugs (especially terrestrial higher plants) have historically been alternatives to anti-infectives.
- These played a significant role in ancient traditional medicine systems, for example:
- Traditional Chinese Medicine (Chinese)
- Ayurvedic Medicine (Indians)
- Egyptian Traditional Medicine (Ancient Egyptian)
Importance of Plants in Modern Pharmacy and Medicine
- WHO data: Up to 80% of the global population uses traditional herbal medicine for primary healthcare.
- Modern medicine: Approximately 50% of modern medicines are either derived from natural origins or based on natural products.
- Recent drug development: The majority of recently introduced natural product-derived drugs resulted from:
- Terrestrial microbe sources
- Higher plants
- Marine animal origins
Examples of Natural Drugs
- Atropine – Atropa belladonna
- Aspirin – Salix spp
- Quinine – Cinchona spp
- Paclitaxel – Taxus brevifolia
- Penicillin – Penicillium spp
- Doxorubicin – Streptomyces spp
- Streptomycin – Streptomyces spp
- Morphine – Papaver somniferum
- Artemisinin – Artemisia annua
- Vinca alkaloids – Catharanthus roseus
Pharmacognosy's History
- Definition: Coined in the early 19th century by Johann Adam Schmidt, the term derives from "pharmakon" (remedy) and "gignosco" (knowledge).
- Established field: A crucial pharmaceutical science within pharmacy education for over a century.
- Evolution of focus: Shifted focus from mainly 19th and early 20th century focus on chemical and biological focus over 60 years.
- Key historical concepts:
- Historical studies are essential to gaining a better understanding of medicines and diseases
- The methods of understanding are archaeology and documented records
- Examples: Ephedra altissima (ephedrine), Egyptian Ebers Papyrus (~1500 BC), and Greek medicine (Dioscorides, Hippocrates and Galen)
Modern Aspects of Pharmacognosy
- Evolved to include phytotherapy, phytomedicine, phytochemistry, and nutraceuticals.
- Increased relevance: A significant increase in the use of herbal remedies by the public, particularly in Europe, North America, and Australasia.
Phytotherapy
- Definition: Primarily focused on using natural extracts as healthcare or health-enhancing agents.
- Role: Integral part of traditional medicine, often a treatment method for common illnesses.
Phytomedicine
- Definition: Herbal medicine with strong therapeutic properties which form a basis for herbal remedies.
- Examples: Aerial parts, leaves, flowers, roots, barks, rhizomes.
Phytochemistry
- Definition: Study of the chemical constituents of plants and their compounds, like morphine, taxol, and artemisinin.
Other Key Concepts
- Natural products: Isolated compounds originated from natural sources including bacteria, fungi, plants, and animals .
- Pure compounds: A single chemical entity, well-defined structure and composition, isolated and purified from natural sources.
- Synthetic compounds: Chemically synthesized substances originating from natural substances.
- Semi-synthetic compounds: Substances partly synthesized in the laboratory using natural compounds as raw materials.
- Nutraceuticals: A substance or part of a food, providing health advantages and preventative effects (e.g, spices, certain plants).
- Crude drugs: Plant-derived substances (or exudates) unmodified in chemical composition, prepared from plant organs.
- Crude drug sources: Plants (e.g., leaves, stems, roots, bark, seeds), animals, and minerals.
- Organized/Unorganized crude drug types: Organized are therapeutic substances from plants. Unorganized are substances like dry latex, gums, resins etc, typically extracted from plants.
Notable Figures and Discoveries
- Artemisinin: A significant antimalarial, discovered by Youyou Tu who was awarded a Nobel Prize for her research.
- Morphine: Derived from opium poppy, a potent analgesic and smooth muscle relaxant.
- Quinine: Derived from Cinchona bark, effective anti-malaria agent.
- Aspirin: Salix spp, the basis of nonsteroidal anti-inflammatory drug, used for pain, fever, and inflammation relief.
- Tubocurarine: Derived from American arrow poison, potent analgesic and myorelaxant, used in anesthesiology.
- Taxol: Derived from Pacific yew tree bark, a notable anticancer drug for breast, lung, and ovarian cancer.
- Physostigmine: Derived from Calabar bean, effective in managing anti-muscarinic toxicity and glaucoma.
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Description
This quiz covers key concepts in Pharmacognosy as part of the B.Pharm PCG 201 course. Topics include Microscopy, Cytomorphology, and the significance of natural products in medicine. Students will demonstrate their understanding of drug classification and preparation processes.