Bone Tumor Systematic Approach Quiz

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40 Questions

Which term is used for osteonecrosis within the diaphysis or metaphysis?

Bone infarct

What is the typical presentation of bone infarcts on imaging?

Central lesion in metaphysis or diaphysis with a well-defined serpentiginous border

What imaging feature characterizes bone infarcts on both T1 and T2 weighted images?

Low signal intensity

What is the main cause of bone infarcts?

Corticosteroid use

In which type of lesions do we see aggressive periosteal reactions and soft tissue masses?

Mixed osteolytic and sclerotic lesions

What type of lesion is characterized by a thick cartilage cap, lytic peripheral part with subtle calcifications, and a zone of high signal intensity on T2-weighted images?

Osteoid osteoma

Which condition may show a periosteal and endosteal reaction leading to reactive sclerosis, obscuring the central nidus in certain localizations?

Osteoid osteoma

Which bone tumor is characterized by a highly malignant formation with a permeative pattern of the transition zone, irregular cortical destruction, and interruption of the periosteum?

Osteosarcoma

What type of lesion may manifest as a large tumor mass infiltrating a significant portion of the bone and extending into the soft tissues?

Osteosarcoma

Which condition can present with a mix of lytic and sclerotic components, often with cortical soft tissue extension and elevation of periosteum from underlying bone?

Osteosarcoma

Which condition can present as an osteolytic lesion with sharp margins and may have septa and ridges?

Brown tumors from hyperparathyroidism

What is the typical presentation of chondroblastoma?

A well-defined osteolytic lesion in the tarsal bone, patella, or epiphysis of a long bone in a 20-year old with joint pain and swelling

Which bone lesion is characterized by being expansile, well-defined, and filled with blood?

Solitary Bone Cyst (SBC)

What is the radiological hallmark of chondrosarcoma?

Formation of a chondroid (cartilagenous) matrix with stippled or popcorn-like calcifications

Which pathology can mimic bone tumors and has a broad spectrum of radiographic features, occurring at any age?

Infection or osteomyelitis

What is the typical appearance of a bone island on imaging?

Round or oval benign lesion consisting of mature bone tissue within the medullary cavity

Which disease can lead to avascular osteonecrosis resulting in osteolytic lesions and permeative cortical destruction patterns?

Bone infarct

How can an enchondroma be differentiated from chondrosarcoma?

Presence of peripheral low signal intensity due to calcifications

Which bone pathology is characterized by a true cyst, frequently presents with a fracture, and has a predilection for the proximal humerus and femur?

Solitary Bone Cyst (SBC)

Which bone tumor is almost always low-grade and known for its primary presentation in the proximal long bones, around the knee, pelvis, and shoulder girdle?

Chondrosarcoma

Which type of bone lesion typically presents as a solitary, benign tumor producing osteoid and bone?

Osteoblastoma

In which age group is bone metastasis more common?

Over 40

Which bone tumor is characterized by multiple lytic 'punched out' lesions in the axial skeleton and diaphysis of long bones?

Multiple Myeloma

Which type of lesion will not show any uptake on a bone scan?

Bone infarct

Which type of bone tumor can be discriminated by the patient being over the age of 40?

Multiple Myeloma

Which type of bone tumor is typically located centric in long bones?

Enchondroma

Which type of mineralization pattern is typically seen in osseous tumors like osteoid osteomas?

Rings-and-arcs

Which type of bone tumor is characterized by a chondroid matrix with rings-and-arcs pattern?

Chondrosarcoma

Which type of bone tumor is commonly eccentrically located in long bones?

Giant cell tumor (GCT)

Which type of bone tumor primarily arises from the periosteum?

Parosteal osteosarcoma

Which type of bone lesion may show uniform cortical bone destruction?

Benign lesion

In ballooning, the addition of new bone occurs at the same rate as the destruction of which cortical bone surface?

Endosteal cortical bone

Which term is used to describe the smooth and uninterrupted 'neocortex' formed in ballooning?

Neoplastic cortex

What is a feature of more aggressive lesions like giant cell tumor (GCT) with regards to ballooning?

Focal interruption in the neocortex

Which condition can present with endosteal scalloping of the cortical bone?

Chondromyxoid myxoma

Avascular osteonecrosis typically affects which part of the bone?

Epiphysis

Mixed lytic-sclerotic lesions are commonly seen in which type of tumor or condition?

Chondrosarcoma

Osteolytic tumors are characterized by which of the following?

Destruction of the bone cortex

Bone infarcts may present with what imaging feature on both T1 and T2 weighted images?

Double line sign

Complete destruction of cortical bone may be seen in high-grade malignant lesions and which other type of lesions?

Fibrous dysplasia (FD)

Test your knowledge on bone tumors with a systematic approach focusing on locations such as centric, eccentric, and juxtacortical in long bones. Identify various types of bone tumors based on their location and characteristics.

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