65 Questions
Why is cartilage considered weaker than bone?
Due to being avascular and having limited healing ability
What is the main function of bones in the human body?
To store and release minerals like calcium and phosphate
Which type of bone marrow is responsible for hematopoiesis?
Red marrow
What type of bone formation develops flat bones of the skull, some facial bones, the mandible, and central portions of clavicle?
Intramembranous ossification
Where do nutrient arteries typically enter a bone?
At the growth end of the bone
What covers the vital organs such as ribs, skull, and vertebral column for protection?
Compact bone
Which type of bone lamellae is associated with concentric plates of bone forming osteons around the central canal?
Concentric lamellae
In bones, what strengthens the extracellular matrix by depositing minerals?
Calcification
What is the term for the formation and development of bone?
Ossification
Why is cartilage considered a precursor model for bone growth?
As it serves as a template for bone formation during fetal development
Which layer gives rise to skeletal, cardiac, smooth muscles, bone, blood, dermis, kidneys, ureters, adrenal cortex, and dura mater during development?
Mesoderm
Which type of artery enters the periosteum in the diaphysis through interosteonic canals?
Periosteal artery
What is the primary role of vitamin D in the body?
Promotes calcium and phosphorus absorption in the intestine
Which type of fracture is characterized by the bone being bent with one side fractured and the other side intact?
Greenstick fracture
During which phase of bone repair does the formation of fibrocartilaginous callus occur?
Restorative Phase
Which age group experiences a stage where bone resorption is greater than bone deposition?
Middle age adults
In what type of fracture does one end of the broken bone get driven into the other end?
Impacted fracture
Which vitamin deficiency can lead to decreased bone density due to the impaired synthesis of bone proteins?
Vitamin K deficiency
What is the main function of osteoclasts in bone remodeling?
Removal of Ca2+ and collagen fibers
Which type of bone is replaced at a higher rate annually?
Spongy bone at 20%
What is the impact of orthodontic braces on bone remodeling?
They increase stress on the bones
In osteoporosis, what is one factor that contributes to the condition?
Decreased hormone production
Which hormone stimulates osteoblast activity in adults?
Thyroid hormone
What is the role of Vitamin C in bone health?
Promotes collagen synthesis
What is the primary function of osteoprogenitors?
Develop into mature bone cells
Which of the following bone cells is responsible for resorbing bone matrix?
Osteoclasts
What is the main inorganic component responsible for providing rigidity to bone?
Calcium phosphate [Ca3(PO4)2]
Where are osteocytes located within bone tissue?
In lacunae, communicating via canaliculi
Which type of bone tissue is abundant in epiphysis and supports/protects red bone marrow?
Spongy bone
What is the basic structural and functional unit of mature compact bone?
Osteon
During endochondral ossification, what happens as chondrocytes hypertrophy?
They start to die due to calcification of ECM
Which stage of endochondral ossification involves the development of the primary ossification center?
Development of medullary cavity
What triggers osteoprogenitor cells to form osteoblasts during endochondral ossification?
Nutrient artery penetration
In endochondral ossification, what type of bone is formed when osteoblasts develop spongy bone around the primary ossification center?
Cancellous bone
Which type of growth in the cartilage model leads to an increase in width?
Appositional growth
When does the diaphysis start to calcify first during endochondral ossification?
6th-8th week
Which structure breaks down trabeculae and replaces most of the diaphysis with compact bone?
Osteoclasts
Which type of ossification develops flat bones of the skull, some facial bones, the mandible, and central portions of the clavicle?
Intramembranous ossification
Where do metaphyseal arteries supply blood in bones?
Between diaphysis and epiphyseal plate
Which layer of bone gives rise to epithelial tissues during embryonic development?
Endoderm
Where do nutrient arteries typically enter bones?
Periosteum through interosteonic canals
What is the primary nutrient artery pathway that supplies blood to bones away from the growth end?
Nutrient arteries
Which is responsible for forming concentric plates of bone around the central canal, creating osteons?
Concentric lamellae
What is the main source of skeletal, cardiac, and smooth muscles during embryonic development?
Mesoderm
What type of growth in bone length involves the replacement of cartilage by bone on the diaphyseal side of the epiphyseal plate?
Interstitial growth
Which zone of the epiphyseal plate is characterized by large chondrocytes undergoing mitosis, often forming a 'stack of coins' appearance?
Zone of proliferating cartilage
What type of bone growth occurs through the deposition of concentric lamellae around blood vessels by osteoblasts?
Appositional growth
Which type of cells differentiate into osteoblasts to secrete collagen fibers and organic molecules for appositional growth in bones?
Periosteal cells
In bone remodeling, which cells destroy bone tissue in the medullary cavity and contribute to increasing the inner diameter as the outer width grows?
Osteoclasts
Which type of growth contributes to an increase in the width of bones and occurs throughout the lifespan?
Appositional growth
What is the final zone in the epiphyseal plate where minerals are deposited, chondrocytes undergo apoptosis, and bone tissue is formed?
Zone of calcified cartilage
Which type of tissues are bones primarily categorized as?
Connective
Where do chondrocytes, the functional cells of cartilage, reside?
Lacunae
Which function of bones involves the covering and protection of vital organs?
Protection
What is the main source and storage of calcium and phosphates in bones?
Calcification
Which type of bone tissue is more flexible and resilient compared to bone?
Hyaline cartilage
Where does hemopoiesis, the production of new red blood cells, primarily occur in adults?
Red bone marrow
What is the organic component responsible for maintaining bone strength and flexibility?
Collagen fibers
Which bone classification is associated with bones that are longer than they are wide?
Long bones
What is the main role of Vitamin D in bone health?
Facilitates Ca2+ and phosphorus absorption in the intestine
Which type of fracture is characterized by one end of the bone being driven into the other?
Impacted fracture
During which phase of bone repair does the formation of a fibrocartilaginous and bony callus occur?
Restorative Phase
What type of bone fracture is characterized by partial bending of the bone with one side fractured and the other side intact?
Greenstick fracture
Which group experiences a stage where bone resorption exceeds bone deposition?
Middle-aged individuals
What happens during the Bone Remodeling Phase of bone repair?
Osteoclasts absorb dead bone portions
Test your knowledge on the structure of bones, including lamellae (sheets of compact bone) and their blood and nerve supply. Learn about the different types of lamellae and how arteries and veins supply blood to bones.
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