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Questions and Answers

What is the primary mechanism by which muscle contraction is initiated?

  • Breakdown of the muscle fiber cell membrane
  • Binding of actin with myosin
  • Action potential spreading from the nerve terminal (correct)
  • Release of calcium from the sarcoplasmic reticulum

Which of the following is a consequence of rhabdomyolysis due to traumatic cause?

  • Electrolyte Imbalance
  • Muscle Swelling (correct)
  • Myalgia
  • Acute Kidney Injury

What is the function of ATP in muscle metabolism?

  • To release myoglobin into systemic circulation
  • To fuel complex muscle contraction and drive the cross-bridge of actin and myosin (correct)
  • To break down the muscle fiber cell membrane
  • To transport calcium from the sarcoplasmic reticulum

Which of the following is a potential cause of rhabdomyolysis?

<p>All of the above (D)</p> Signup and view all the answers

What is the result of the breakdown of the muscle fiber cell membrane in rhabdomyolysis?

<p>Entry of sodium and calcium into the myocyte (A)</p> Signup and view all the answers

What is the 'all or nothing' principle in muscle physiology?

<p>The principle that muscle contraction is an all-or-nothing response (C)</p> Signup and view all the answers

Which type of bone fracture typically occurs in young males and old people?

<p>Tibial fractures (A)</p> Signup and view all the answers

What is the primary difference between primary direct healing and secondary indirect healing of bone fractures?

<p>Formation of a callus (A)</p> Signup and view all the answers

During which phase of bone healing does the hematoma form?

<p>Inflammatory phase (D)</p> Signup and view all the answers

What is the term for the temporary displacement of a bone from its joint?

<p>Dislocation (D)</p> Signup and view all the answers

Which type of injury is characterized by the inflammation of a tendon at the location of its attachment to the bone?

<p>Epicondylitis (B)</p> Signup and view all the answers

What is the term for the inflammation of bursa sacs that are located on tendons, muscles, or bony prominences?

<p>Bursitis (C)</p> Signup and view all the answers

What is the primary cause of muscular cell death in rhabdomyolysis?

<p>Depletion of ATP leading to increased intracellular calcium (B)</p> Signup and view all the answers

What is the primary function of osteocytes in bone maintenance?

<p>To maintain bone by signaling osteoblasts and osteoclasts (B)</p> Signup and view all the answers

What is the main difference between osteoporosis and osteomalacia?

<p>Osteoporosis is caused by low bone density, while osteomalacia is caused by inadequate mineralization (C)</p> Signup and view all the answers

What is the primary function of RANKL in bone metabolism?

<p>To activate osteoclasts and promote bone resorption (C)</p> Signup and view all the answers

What is the characteristic feature of Paget's disease?

<p>Excessive bone resorption and formation (D)</p> Signup and view all the answers

What is the origin of all bone tumors?

<p>Mesoderm (A)</p> Signup and view all the answers

What is the primary function of osteoprotegerin (OPG) in bone metabolism?

<p>To block the effects of RANKL and osteoclast activity (A)</p> Signup and view all the answers

What is the characteristic symptom of rhabdomyolysis?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary cause of osteoporosis?

<p>All of the above (D)</p> Signup and view all the answers

What is the criteria for malignancy in bone tumors?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT a characteristic of noninflammatory joint disease?

<p>Presence of systemic signs and symptoms (A)</p> Signup and view all the answers

What is the primary mechanism of cartilage destruction in osteoarthritis?

<p>Proteolytic destruction of cartilage matrix and chondrocyte death (B)</p> Signup and view all the answers

Which of the following is a characteristic of rheumatoid arthritis but not osteoarthritis?

<p>Hypersensitivity reaction to antigens (B)</p> Signup and view all the answers

What is the primary source of uric acid in the body?

<p>Purine breakdown (B)</p> Signup and view all the answers

Which of the following is a complication of osteomyelitis?

<p>Microscopic chambers in the bone are hard to penetrate with antibiotics (A)</p> Signup and view all the answers

What is the primary mechanism of joint damage in gout?

<p>Crystal formation in the synovial fluid (D)</p> Signup and view all the answers

Which of the following is a risk factor for osteoarthritis?

<p>Hormonal status (C)</p> Signup and view all the answers

What is the primary mechanism of bone destruction in osteomyelitis?

<p>Thrombosis and necrosis caused by bacterial infection (A)</p> Signup and view all the answers

Which of the following is a characteristic of osteomyelitis but not osteoarthritis?

<p>Infection of the bone (A)</p> Signup and view all the answers

What is the primary mechanism of joint inflammation in rheumatoid arthritis?

<p>Hypersensitivity reaction to antigens (B)</p> Signup and view all the answers

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