Podcast
Questions and Answers
What is the function of PTH?
What is the function of PTH?
- Indirectly increases phosphate reabsorption in the kidneys, stimulates bone resorption, decreases plasma calcium levels
- Mobilizes calcium from bone, enhances renal reabsorption of calcium, indirectly increases intestinal absorption of calcium (correct)
- Stimulates bone formation, decreases plasma calcium levels, decreases intestinal absorption of calcium
- Inhibits calcium reabsorption in the kidneys, decreases plasma calcium levels, decreases bone resorption
What is the function of calcitriol (1,25-dihydroxycholecalciferol/Vitamin D3)?
What is the function of calcitriol (1,25-dihydroxycholecalciferol/Vitamin D3)?
- Decreases plasma calcium levels, inhibits bone formation
- Regulated at the kidneys by PTH, increases intestinal absorption of calcium (correct)
- Enhances renal excretion of calcium, decreases phosphate reabsorption in the kidneys
- Stimulates bone resorption, inhibits calcium reabsorption in the intestines
What activates adenylyl cyclase and intracellular calcium mobilization in response to PTH binding?
What activates adenylyl cyclase and intracellular calcium mobilization in response to PTH binding?
- PTH (correct)
- Calcitonin
- PTH-related peptide (PTHrP)
- Calcitriol
Where is the Ca2+-Sensing Receptor (CaSR) expressed?
Where is the Ca2+-Sensing Receptor (CaSR) expressed?
Which hormone is primarily responsible for enhancing Ca2+ uptake from the small intestine?
Which hormone is primarily responsible for enhancing Ca2+ uptake from the small intestine?
What is the major effect of PTH on phosphate handling?
What is the major effect of PTH on phosphate handling?
Which hormone is released when plasma Ca2+ increases?
Which hormone is released when plasma Ca2+ increases?
What is the primary target of 1, 25-(OH)2D3 (Vitamin D)?
What is the primary target of 1, 25-(OH)2D3 (Vitamin D)?
What is the most common cause of hypercalcemia in primary hyperparathyroidism?
What is the most common cause of hypercalcemia in primary hyperparathyroidism?
What is the treatment for hypoparathyroidism?
What is the treatment for hypoparathyroidism?
What is the most important etiologic factor in osteoporosis?
What is the most important etiologic factor in osteoporosis?
What is the mechanism of action of Bisphosphonates?
What is the mechanism of action of Bisphosphonates?
What is the primary action of PTH Derivatives like teriparatide (Forteo)?
What is the primary action of PTH Derivatives like teriparatide (Forteo)?
What is the most common cause of osteomalacia in children?
What is the most common cause of osteomalacia in children?
What is the primary effect of estrogen deficiency in osteoporosis?
What is the primary effect of estrogen deficiency in osteoporosis?
What is the cause of hypercalcitoninemia in Medullary Carcinoma (Thyroid)?
What is the cause of hypercalcitoninemia in Medullary Carcinoma (Thyroid)?
What is the primary function of parathyroid hormone (PTH)?
What is the primary function of parathyroid hormone (PTH)?
What is the function of the Ca2+-Sensing Receptor (CaSR)?
What is the function of the Ca2+-Sensing Receptor (CaSR)?
What is the main site of production regulation for calcitriol (1,25-dihydroxycholecalciferol/Vitamin D3)?
What is the main site of production regulation for calcitriol (1,25-dihydroxycholecalciferol/Vitamin D3)?
Which hormone is considered most important for calcium balance in adults?
Which hormone is considered most important for calcium balance in adults?
What is the primary target of parathyroid hormone (PTH)?
What is the primary target of parathyroid hormone (PTH)?
What is the function of oxyphil cells in the parathyroid glands?
What is the function of oxyphil cells in the parathyroid glands?
What activates adenylyl cyclase and intracellular calcium mobilization in response to parathyroid hormone (PTH) binding?
What activates adenylyl cyclase and intracellular calcium mobilization in response to parathyroid hormone (PTH) binding?
Which hormone enhances renal reabsorption of calcium?
Which hormone enhances renal reabsorption of calcium?
What is the primary ligand for the Ca2+-Sensing Receptor (CaSR)?
What is the primary ligand for the Ca2+-Sensing Receptor (CaSR)?
What is the size range of chief cells in the parathyroid glands?
What is the size range of chief cells in the parathyroid glands?
Which hormone controls calcium homeostasis and is very sensitive to small changes in serum calcium concentration?
Which hormone controls calcium homeostasis and is very sensitive to small changes in serum calcium concentration?
What is the physiological function of calcium in the body?
What is the physiological function of calcium in the body?
What is the primary function of Calcitonin?
What is the primary function of Calcitonin?
What is the main effect of Fibroblast Growth Factor-23 (FGF-23)?
What is the main effect of Fibroblast Growth Factor-23 (FGF-23)?
What is the primary target of 1, 25-(OH)2D3 (Vitamin D)?
What is the primary target of 1, 25-(OH)2D3 (Vitamin D)?
What is the main effect of PTH on phosphate handling?
What is the main effect of PTH on phosphate handling?
What is the mechanism of action of Bisphosphonates?
What is the mechanism of action of Bisphosphonates?
What is the most common cause of hypercalcemia in primary hyperparathyroidism?
What is the most common cause of hypercalcemia in primary hyperparathyroidism?
What is the primary effect of estrogen deficiency in osteoporosis?
What is the primary effect of estrogen deficiency in osteoporosis?
What is the primary action of PTH Derivatives like teriparatide (Forteo)?
What is the primary action of PTH Derivatives like teriparatide (Forteo)?
Where is the Ca2+-Sensing Receptor (CaSR) predominantly expressed?
Where is the Ca2+-Sensing Receptor (CaSR) predominantly expressed?
What is the cause of hypercalcitoninemia in Medullary Carcinoma (Thyroid)?
What is the cause of hypercalcitoninemia in Medullary Carcinoma (Thyroid)?
What is the most important etiologic factor in osteoporosis?
What is the most important etiologic factor in osteoporosis?
What is the primary function of Osteocytes?
What is the primary function of Osteocytes?
