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Questions and Answers
What percentage of total body water is typically found within the intracellular fluid (ICF)?
What percentage of total body water is typically found within the intracellular fluid (ICF)?
Which of the following best describes the primary function of the capillary membrane in relation to plasma proteins?
Which of the following best describes the primary function of the capillary membrane in relation to plasma proteins?
Which of the following is NOT a direct function of body water?
Which of the following is NOT a direct function of body water?
How do the protein concentrations compare between plasma and the interstitial fluid (ISF)?
How do the protein concentrations compare between plasma and the interstitial fluid (ISF)?
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What is the main cation found in the extracellular fluid (ECF)?
What is the main cation found in the extracellular fluid (ECF)?
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Which ion is present in smaller amounts within the intracellular fluid (ICF) compared to the extracellular fluid (ECF)?
Which ion is present in smaller amounts within the intracellular fluid (ICF) compared to the extracellular fluid (ECF)?
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How does the pH of the intracellular fluid (ICF) compare to the pH of the extracellular fluid (ECF)?
How does the pH of the intracellular fluid (ICF) compare to the pH of the extracellular fluid (ECF)?
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Which of the following is NOT typically a component found within the extracellular fluid (ECF)?
Which of the following is NOT typically a component found within the extracellular fluid (ECF)?
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What primarily drives the continuous fluid exchange across cell membranes?
What primarily drives the continuous fluid exchange across cell membranes?
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What is the immediate effect of injecting a hypertonic NaCl solution intravenously?
What is the immediate effect of injecting a hypertonic NaCl solution intravenously?
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What happens to cell volume when a hypotonic NaCl solution is administered intravenously?
What happens to cell volume when a hypotonic NaCl solution is administered intravenously?
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How does injecting an isotonic solution affect the osmolality of body fluids?
How does injecting an isotonic solution affect the osmolality of body fluids?
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What determines the direction of water movement during osmosis?
What determines the direction of water movement during osmosis?
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If a membrane separates two compartments, and compartment B has a higher solute concentration, what will happen to water?
If a membrane separates two compartments, and compartment B has a higher solute concentration, what will happen to water?
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What happens to a cell when the water concentration outside the cell is lower than inside the cell?
What happens to a cell when the water concentration outside the cell is lower than inside the cell?
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How does the concentration of solute affect the concentration of water in a solution?
How does the concentration of solute affect the concentration of water in a solution?
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Which of the following best describes an 'effective' osmole?
Which of the following best describes an 'effective' osmole?
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Why do plasma proteins act as effective osmoles within the vascular compartment?
Why do plasma proteins act as effective osmoles within the vascular compartment?
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For osmosis to occur, what two conditions must be met?
For osmosis to occur, what two conditions must be met?
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What is osmotic pressure defined as?
What is osmotic pressure defined as?
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Under normal conditions, how does the body maintain a constant total body water (TBW) level?
Under normal conditions, how does the body maintain a constant total body water (TBW) level?
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Which of these is the main source of daily water gain for the body?
Which of these is the main source of daily water gain for the body?
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What is the primary source of insensible water loss?
What is the primary source of insensible water loss?
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What is the normal daily water loss through urine?
What is the normal daily water loss through urine?
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Flashcards
Hypertonic Solution
Hypertonic Solution
A type of solution where the solute concentration is higher outside the cell, causing water to move out of the cell.
Hypotonic Solution
Hypotonic Solution
A type of solution where the solute concentration is lower outside the cell, causing water to move into the cell.
Isotonic Solution
Isotonic Solution
A solution with the same solute concentration as the inside of the cell, resulting in no net movement of water.
Osmosis
Osmosis
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Osmolality
Osmolality
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Intracellular Fluid (ICF)
Intracellular Fluid (ICF)
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Extracellular Fluid (ECF)
Extracellular Fluid (ECF)
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Osmotic Equilibrium
Osmotic Equilibrium
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Interstitial Fluid (ISF)
Interstitial Fluid (ISF)
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Plasma
Plasma
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Sodium (Na+)
Sodium (Na+)
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Chloride (Cl-)
Chloride (Cl-)
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Potassium (K+)
Potassium (K+)
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Cerebrospinal Fluid
Cerebrospinal Fluid
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Effective Osmole
Effective Osmole
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Osmotic Pressure
Osmotic Pressure
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Water Balance
Water Balance
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Exogenous Water
Exogenous Water
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Endogenous Water
Endogenous Water
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Insensible Water Loss
Insensible Water Loss
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Comfortable Zone
Comfortable Zone
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Study Notes
Body Fluids
- Body fluids are crucial for maintaining homeostasis
- Total body water (TBW) is approximately 60% of body weight in adults
- Intracellular fluid (ICF) is about 2/3 of TBW
- Extracellular fluid (ECF) is approximately 1/3 of TBW
- Interstitial fluid (ISF) comprises about 3/4 of ECF
- Vascular compartment contains blood volume, including plasma and red blood cells; about 1/4 of ECF
- Cell membranes and capillary membranes act as barriers regulating fluid and solute exchange
Functions of Body Water
- Medium for chemical and enzymatic reactions
- Essential for diffusion and filtration
- Involved in regulating pH and osmolality
- Regulates body temperature through heat absorption, distribution, and evaporation
- Lubricant in joints and potential spaces (e.g., pleura)
- Refractive medium in the eye
- Cerebrospinal fluid acts as a mechanical buffer protecting the brain
- Medium for O2 and CO2 exchange in lungs and tissues
Composition of Extracellular Fluid (ECF)
- Composition is similar throughout ECF, except for protein concentration
- Primarily composed of Na+ (about 142 mEq/L) as the main cation and Cl- (about 106 mEq/L) as the main anion
- Other cations include K+ (about 4.2 mEq/L), Ca2+, and Mg2+
- Other anions include HCO3-(about 24 mEq/L), proteins, and small amounts of HPO4-2 and SO4-2
- Also contains non-electrolytes like glucose, cholesterol, urea, uric acid, creatinine, bile pigments, and phospholipids
- ECF pH is approximately 7.4
- ECF osmolality is about 300 mOsm/L
Composition of Intracellular Fluid (ICF)
- Main cations are K+ (about 140 mEq/L) and Mg2+ (about 20 mEq/L) along with small amounts of Na+ and Ca2+
- Main anions include HPO4-2 and proteins, along with small amounts of Cl-,HCO3-, and SO4-2
- ICF pH is less than that of ECF (around 7)
- ICF osmolality is similar to ECF osmolality
Fluid Exchange Between ICF and ECF
- Cell membranes are highly permeable to water, leading to continuous fluid exchange and equal osmolality
- Factors such as hypertonic or hypotonic NaCl injections alter osmolality, causing water to move between ICF and ECF until equilibrium is reached
Osmosis
- Osmosis is the diffusion of water across a semipermeable or selectively permeable membrane
- Movement of water from a region of higher-water concentration to a region of lower-water concentration
- Water concentration in a solution is determined by the solute concentration
- The number of particles, not the type of particle is crucial to osmolality
Osmotic Pressure
- Osmotic pressure is the amount of pressure needed to stop osmosis in a sodium chloride solution
- Differences in osmotic pressure create a driving force for water movement across a membrane
Water Balance
- Normal water balance involves equal daily water gain and loss (approximately 2300 mL/day)
- Water intake is primarily from exogenous sources such as ingested fluids and food
- Water loss occurs through various mechanisms like urinary, fecal, respiratory, and evaporative losses
Water Gain sources
- Drinking fluids: approximately 1400 ml daily
- Foodwater: approximately 600 ml daily
- Endogenous synthesis: approximately 300 ml daily
Water Loss sources
- Urine: approximately 1400 ml daily
- Feces: approximately 100 ml daily
- Respiratory tract: approximately 350 ml daily
- Skin: approximately 450 ml daily, often called insensible water loss
Summary
- Important role of body fluids in maintaining homeostasis
- Composition and functions of intracellular and extracellular fluids
- Mechanisms of fluid exchange, particularly osmosis, for maintaining equilibrium
- Water balance as an aspect of overall body homeostasis
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Description
Explore the essential role of body fluids in maintaining homeostasis, including the distribution of total body water and the specific functions of intracellular and extracellular fluids. This quiz covers the mechanisms that regulate fluid exchange and the various functions of body water in crucial physiological processes.