Podcast
Questions and Answers
Which indicator would be appropriate to measure interstitial fluid?
Which indicator would be appropriate to measure interstitial fluid?
Infusion of isotonic saline would primarily alter which of the following?
Infusion of isotonic saline would primarily alter which of the following?
What factor would decrease interstitial protein concentration if the capillary reflection coefficient is 1?
What factor would decrease interstitial protein concentration if the capillary reflection coefficient is 1?
Which infusion would cause the greatest increase in plasma osmolarity?
Which infusion would cause the greatest increase in plasma osmolarity?
Signup and view all the answers
Infusion of 15 L of isotonic saline would result in what after equilibration?
Infusion of 15 L of isotonic saline would result in what after equilibration?
Signup and view all the answers
Study Notes
Measurement of Interstitial Fluid
- Indicators for measuring interstitial fluid include 3H2O and Na or 125I-albumin.
- 125I-albumin is a specific marker used in assessing interstitial fluid concentrations.
Effects of Isotonic Saline Infusion
- Infusion of isotonic saline alters extracellular fluid volume, having no significant change to intracellular fluid volume.
- Extracellular fluid osmolarity remains stable during isotonic saline infusion.
Decrease in Interstitial Protein Concentration
- Increasing capillary hydrostatic pressure decreases interstitial protein concentration.
- Increasing interstitial hydrostatic pressure or capillary oncotic pressure also affects protein concentration.
Plasma Osmolarity Increases
- The greatest increase in plasma osmolarity is caused by increasing plasma Na+ by 10 mEq/L.
- Other solutes like K+, glucose, and urea produce smaller osmolarity changes.
Fluid Shifts and Infusions
- Hypotonic fluids cause fluid shifts from extracellular to intracellular compartments.
- Isotonic and hypertonic fluids do not lead to significant fluid shifts in this direction.
Outcomes of Isotonic Saline Infusion
- Infusion of 15 L isotonic saline leads to increased plasma Na+ after equilibration.
- It results in fluid shifts from intracellular to extracellular fluid compartments and expands extracellular fluid volume.
Effects of Glucose Addition
- Adding 500 mEq of glucose to plasma increases extracellular fluid volume after equilibrating.
- It also causes a decrease in plasma Na+ and elevates plasma osmolarity.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz covers the measurement and effects of interstitial fluid dynamics, including the role of isotonic saline infusion, osmolarity changes, and protein concentration shifts. Test your understanding of fluid shifts and how various pressures influence interstitial protein levels.
