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Questions and Answers
In the one-compartment open model, what does the plot of drug concentration (C) versus time (t) look like on a linear paper?
In the one-compartment open model, what does the plot of drug concentration (C) versus time (t) look like on a linear paper?
- Exponential
- Logarithmic
- Linear
- Curvelinear (correct)
What is the unit of the elimination rate constant (Ke)?
What is the unit of the elimination rate constant (Ke)?
- mg/min
- mg/L
- min^-1 (correct)
- L/min
What does a linear plot of drug concentration (C) versus time (t) on a semi-log paper indicate?
What does a linear plot of drug concentration (C) versus time (t) on a semi-log paper indicate?
- Logarithmic decay
- Exponential growth
- Logarithmic growth
- Exponential decay (correct)
What characterizes the elimination phase in the one-compartment open model?
What characterizes the elimination phase in the one-compartment open model?
What happens to the drug concentration in plasma during intravenous (IV) infusion at a zero-order rate?
What happens to the drug concentration in plasma during intravenous (IV) infusion at a zero-order rate?
What is the time required to reach steady-state drug concentration in the blood primarily dependent on in the one-compartment open model?
What is the time required to reach steady-state drug concentration in the blood primarily dependent on in the one-compartment open model?
What happens to the time needed to reach steady state if a higher infusion rate is used in the one-compartment open model?
What happens to the time needed to reach steady state if a higher infusion rate is used in the one-compartment open model?
What occurs when the rate of infusion equals the rate of elimination during IV infusion?
What occurs when the rate of infusion equals the rate of elimination during IV infusion?
What happens to the amount of drug in the body when a constant rate of infusion is started and there is no elimination?
What happens to the amount of drug in the body when a constant rate of infusion is started and there is no elimination?
What is the primary advantage of giving a drug by intravenous infusion at a zero-order rate?
What is the primary advantage of giving a drug by intravenous infusion at a zero-order rate?
What is the time required to reach steady-state drug concentration in the blood if the rate of infusion is increased?
What is the time required to reach steady-state drug concentration in the blood if the rate of infusion is increased?
What does the plateau level during IV infusion at a constant rate indicate?
What does the plateau level during IV infusion at a constant rate indicate?
What is a compartment in the context of body composition?
What is a compartment in the context of body composition?
What does the simplest model predict the body as?
What does the simplest model predict the body as?
What does the one compartment open model assume about changes in plasma levels of a drug?
What does the one compartment open model assume about changes in plasma levels of a drug?
What does 'open' reflect in the one compartment open model?
What does 'open' reflect in the one compartment open model?
In the context of various one compartment open models, what does 'intravenous adm' stand for?
In the context of various one compartment open models, what does 'intravenous adm' stand for?
What is the main characteristic of a compartment in the body?
What is the main characteristic of a compartment in the body?
What is the key feature of the simplest model for body composition?
What is the key feature of the simplest model for body composition?
What is the assumption of the one compartment open model about drug concentration in plasma and other body tissues?
What is the assumption of the one compartment open model about drug concentration in plasma and other body tissues?
What does 'open' imply in the one compartment open model?
What does 'open' imply in the one compartment open model?
What is the meaning of 'intravenous adm' in the context of various one compartment open models?
What is the meaning of 'intravenous adm' in the context of various one compartment open models?
Which statement best describes a compartment in the body?
Which statement best describes a compartment in the body?
What is the primary implication of the simplest model for body composition?
What is the primary implication of the simplest model for body composition?
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