BMS 202 Cell Biology: DNA and Chromosomes

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Questions and Answers

What type of bond links nucleotides in DNA?

  • Peptide bond
  • Phosphodiester bond (correct)
  • Ionic bond
  • Hydrogen bond

How many bases are there per turn in the DNA double helix?

  • 10 (correct)
  • 20
  • 5
  • 15

What is the function of specialized proteins in eukaryotic cells in relation to DNA?

  • Generate new chromosomes
  • Transcribe the DNA
  • Replicate the DNA
  • Generate a series of coils and loops (correct)

What is the total genetic information in a cell called?

<p>Genome (D)</p> Signup and view all the answers

What are repeated sequences at the end of chromosomes used for?

<p>Cap the ends to save them from being mistakenly attacked (A)</p> Signup and view all the answers

What is the function of centromeres in mitotic chromosomes?

<p>Help in chromosome segregation (D)</p> Signup and view all the answers

What is the name of the complex of DNA and protein in a cell's nucleus?

<p>Chromatin (B)</p> Signup and view all the answers

How many meters of DNA does each human cell contain?

<p>~2 meters (D)</p> Signup and view all the answers

What do telomeres cap the ends of?

<p>Chromosomes (C)</p> Signup and view all the answers

What kind of bonds link nucleotides in DNA?

<p>Covalent bonds (B)</p> Signup and view all the answers

What is the mysterious material that turned harmless bacteria into pathogenic ones, as described in the text?

<p>DNA (C)</p> Signup and view all the answers

What did Avery, MacLeod, and McCarty demonstrate to be the genetic material?

<p>DNA (D)</p> Signup and view all the answers

Who definitively showed that genes are made of DNA?

<p>Hershey and Chase (D)</p> Signup and view all the answers

How are the two strands of the DNA double helix held together?

<p>Hydrogen bonds (D)</p> Signup and view all the answers

What are genes made of?

<p>DNA (B)</p> Signup and view all the answers

What did biologists recognize about inherited traits before understanding the DNA structure?

<p>Chromosomes contain both DNA and protein (D)</p> Signup and view all the answers

What are the most frequent chemical reactions known to create serious DNA damage in cells?

<p>Depurination and deamination (A)</p> Signup and view all the answers

What is the first basic step involved in repairing DNA damage?

<p>The damage is recognized and removed (B)</p> Signup and view all the answers

What is the consequence of leaving a DNA mismatch without correction?

<p>It will result in a permanent mutation (B)</p> Signup and view all the answers

Which type of repair plays an important role in preventing cancer?

<p>Mismatch repair (A)</p> Signup and view all the answers

What can cause the formation of thymine dimers in DNA?

<p>Ultraviolet radiation in sunlight (C)</p> Signup and view all the answers

What is the last step involved in repairing DNA damage?

<p>DNA ligase seals nick (D)</p> Signup and view all the answers

Which strategy for repairing double-strand DNA breaks is known for rapidly sticking before drifting apart and often leading to nucleotide loss?

<p>Nonhomologous end joining (A)</p> Signup and view all the answers

What occurs shortly after DNA replication and before cell division, allowing for error-free repair of DNA double-strand breaks?

<p>Homologous recombination (B)</p> Signup and view all the answers

What can lead to the fragmentation of chromosomes and is difficult to repair?

<p>Nonhomologous end joining (C)</p> Signup and view all the answers

Which process relies on genetic redundancy and is used for repairing DNA mismatches?

<p>DNA mismatch repair (D)</p> Signup and view all the answers

What less soluble type of hemoglobin is associated with sickle-cell anemia?

<p>Sickle-cell hemoglobin (B)</p> Signup and view all the answers

What type of repair strategy provides an 'error-free' approach for fixing DNA double-strand breaks?

<p>Homologous recombination (D)</p> Signup and view all the answers

Which specialized enzyme helps the broken 3’ strand to invade the unbroken homologous DNA and search for complementarity during DNA repair?

<p>Homologous recombination (D)</p> Signup and view all the answers

'Quick and dirty' repair of double-strand DNA breaks often leads to the loss of which component?

<p>Nucleotides (C)</p> Signup and view all the answers

'Error-free' repair of double-strand DNA breaks occurs shortly after which cellular process?

<p>Cell division (B)</p> Signup and view all the answers

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