BMS 111 Histology Final Revision Part 2: Epithelial Cell Surfaces and Celiac Disease

Cell Junctions

• Fasciae adherentes, a type of anchoring junction, form a spot-like junction similar to Zonula adherens.
• The main function of Tight junctions in the columnar cells of the intestine is to prevent the passage of molecules between cells.
• Celiac disease is caused by an immune response to gluten.
• Desmosomes (Macula adherens) contain transmembrane protein linkers such as cadherins.
• Tight junctions in the endothelium of blood capillaries in the brain prevent paracellular transport.
• The function of Hemidesmosomes is to attach epithelial cells to the underlying basement membrane.
• Basal infoldings are found in the kidney and are specialized for reabsorption and ion transport.
• Gap junctions (nexus) are composed of a cluster of connexons that form a channel.
• Fibroblasts mainly synthesize collagen fibers.
• The function of occluding (tight) junctions is to prevent the passage of molecules between cells.
• Cadherin sites are located on the surface of cells.
• The main function of intermediate filaments in hemidesmosomes is to provide mechanical strength.
• Gap junctions allow for direct communication between cells through the exchange of ions and small molecules.
• C.T. stands for Connective Tissue in the context of the text.