Blood Pressure Regulation
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Questions and Answers

Which chamber of the heart receives oxygenated blood from the pulmonary veins?

  • Left ventricle
  • Right ventricle
  • Left atrium (correct)
  • Right atrium
  • What is the primary goal of the pulmonary circulation?

  • To carry nutrients from the digestive tract to the tissues
  • To carry metabolic waste products from the tissues to their point of elimination
  • To carry oxygen from the lungs to the tissues
  • To oxygenate blood and remove carbon dioxide (correct)
  • Which segment of the vascular system has lower pressure and vascular resistance compared to the systemic circuit?

  • Pulmonary circulation (correct)
  • Arteries
  • Systemic circulation
  • Veins
  • What is the purpose of blood flow redistribution in the systemic circulation?

    <p>To direct blood to areas with greater metabolic need</p> Signup and view all the answers

    Which layer of blood vessels contains concentric layers of smooth muscle cells?

    <p>Tunica media</p> Signup and view all the answers

    What is the primary site of systemic vascular resistance?

    <p>Arterioles</p> Signup and view all the answers

    Which layer of blood vessels forms a barrier that controls the passage of solutes and cells from the circulation into the subendothelial space?

    <p>Tunica intima</p> Signup and view all the answers

    What is the relationship between wall tension (T), pressure (P), radius (r), and wall thickness (h) in blood vessels?

    <p>T = P + r + h</p> Signup and view all the answers

    Which of the following factors has the greatest impact on vascular resistance?

    <p>Radius of the vessel</p> Signup and view all the answers

    Where does the greatest drop in mean arterial pressure (MAP) occur in the cardiovascular circuit?

    <p>Arterioles</p> Signup and view all the answers

    According to the Law of Laplace, which of the following occurs when the arterial wall weakens in response to increased pressure, causing a vicious cycle of dilation, increased radius, increased tension, and ultimately a weakened wall?

    <p>Aneurysm</p> Signup and view all the answers

    Which of the following is NOT a short-term regulator of blood pressure?

    <p>Aldosterone</p> Signup and view all the answers

    Which blood vessels are less compliant than veins but are subjected to greater pressure changes as they receive the stroke volume of the heart during systole?

    <p>Arteries</p> Signup and view all the answers

    What is the equation for cardiac output (CO)?

    <p>CO = heart rate × stroke volume</p> Signup and view all the answers

    What is the relationship between blood flow velocity and cross-sectional area?

    <p>Inversely related</p> Signup and view all the answers

    What is the most important biochemical mediator produced by endothelial cells and smooth muscle layers that promotes vasodilation, maintains vessel patency and vascular wall health, and lowers blood pressure?

    <p>Nitric oxide (NO)</p> Signup and view all the answers

    Which receptor is responsible for vasoconstriction and increased resistance in the vascular system?

    <p>NE α1</p> Signup and view all the answers

    Which hypothesis of autoregulation suggests that decreased pressure and flow result in buildup of vasodilator metabolites that produce vasodilation?

    <p>Metabolic hypothesis</p> Signup and view all the answers

    Which mediator acts as a potent vasoconstrictor and is the key regulator of adrenal aldosterone secretion in the RAAS?

    <p>Angiotensin II (ATII)</p> Signup and view all the answers

    Which mediator is responsible for reducing circulating volume by stimulating natriuresis and diuresis?

    <p>Atrial natriuretic peptide/BNP</p> Signup and view all the answers

    Which mediator is tonically produced by normal endothelial cells and promotes vasodilation?

    <p>Nitric oxide (NO)</p> Signup and view all the answers

    Which mediator is released by mast cells in areas of trauma or allergic responses and contributes to inflammatory and allergic vasodilation?

    <p>Histamine</p> Signup and view all the answers

    Which mediator is released by white blood cells in the process of inflammatory responses and contributes to inflammatory and allergic vasodilation?

    <p>PGE2 and PGI2</p> Signup and view all the answers

    Which of the following is the most likely cause of the patient's fainting spell?

    <p>Increased firing of parasympathetic fibers to the heart</p> Signup and view all the answers

    What is the effect of sympathetic stimulation on the sinoatrial node?

    <p>Increases heart rate</p> Signup and view all the answers

    What is the effect of sympathetic stimulation on vascular smooth muscle?

    <p>Increases vascular tone</p> Signup and view all the answers

    Which hypothesis of hypertension suggests that increased sympathetic tone leads to vasoconstriction and renin-angiotensin-aldosterone system (RAAS) activity?

    <p>Generalized autoregulation</p> Signup and view all the answers

    Which of the following is a potential contributing factor to hypertension seen as a component of the metabolic syndrome?

    <p>All of the above</p> Signup and view all the answers

    Which layer of blood vessels contains concentric layers of smooth muscle cells?

    <p>Tunica media</p> Signup and view all the answers

    What is the relationship between wall tension (T), pressure (P), radius (r), and wall thickness (h) in blood vessels?

    <p>T = P * r * h</p> Signup and view all the answers

    Which of the following is the most likely cause of the patient's fainting spell?

    <p>Decreased blood pressure</p> Signup and view all the answers

    Which vessel receives output from the left ventricle and branches into numerous parallel vascular circuits?

    <p>Aorta</p> Signup and view all the answers

    What is the primary role of the pulmonary circulation?

    <p>To carry oxygen from the lungs to the tissues</p> Signup and view all the answers

    What is the range of mean arterial pressure in which cerebral autoregulation maintains constant cerebral blood flow?

    <p>60-80 mmHg</p> Signup and view all the answers

    Which hypothesis of hypertension suggests that increased sympathetic tone leads to vasoconstriction and renin-angiotensin-aldosterone system (RAAS) activity?

    <p>Neurogenic hypothesis</p> Signup and view all the answers

    Which of the following mediators is responsible for vasoconstriction and increased resistance in the vascular system?

    <p>Thromboxane A2 (TXA2)</p> Signup and view all the answers

    Which of the following is NOT a potential contributing factor to hypertension seen as a component of the metabolic syndrome?

    <p>Low levels of renin</p> Signup and view all the answers

    Which hypothesis of autoregulation suggests that acute pressure-induced stretch of the arterial and arteriolar walls stimulates immediate constriction, while a rapid pressure drop elicits vasodilation?

    <p>Myogenic hypothesis</p> Signup and view all the answers

    According to the Law of Laplace, which of the following occurs when the arterial wall weakens in response to increased pressure, causing a vicious cycle of dilation, increased radius, increased tension, and ultimately a weakened wall?

    <p>Increased wall tension</p> Signup and view all the answers

    Which of the following factors has the greatest impact on vascular resistance?

    <p>Radius of the vessel</p> Signup and view all the answers

    What is the equation for cardiac output (CO)?

    <p>CO = heart rate x stroke volume</p> Signup and view all the answers

    Which of the following is the most likely cause of the patient's fainting spell?

    <p>Increased parasympathetic tone</p> Signup and view all the answers

    What is the effect of sympathetic stimulation on vascular smooth muscle?

    <p>Vasoconstriction</p> Signup and view all the answers

    Which mediator is responsible for reducing circulating volume by stimulating natriuresis and diuresis?

    <p>Atrial natriuretic peptide/BNP</p> Signup and view all the answers

    Which mediator is released by white blood cells in the process of inflammatory responses and contributes to inflammatory and allergic vasodilation?

    <p>Histamine</p> Signup and view all the answers

    Which receptor is responsible for vasoconstriction and increased resistance in the vascular system?

    <p>a1 receptor</p> Signup and view all the answers

    According to the Law of Laplace, which of the following occurs when the arterial wall weakens in response to increased pressure, causing a vicious cycle of dilation, increased radius, increased tension, and ultimately a weakened wall?

    <p>Aneurysm</p> Signup and view all the answers

    What is the relationship between blood flow velocity and cross-sectional area?

    <p>Inversely related</p> Signup and view all the answers

    What is the most important biochemical mediator produced by endothelial cells and smooth muscle layers that promotes vasodilation, maintains vessel patency and vascular wall health, and lowers blood pressure?

    <p>Nitric oxide</p> Signup and view all the answers

    Which of the following is a compensatory response to an acute drop in blood pressure?

    <p>Increased firing of sympathetic fibers to vascular smooth muscle</p> Signup and view all the answers

    Which of the following hypotheses of hypertension suggests that increased sympathetic tone leads to vasoconstriction and renin-angiotensin-aldosterone system (RAAS) activity?

    <p>Chronically increased sympathetic tone that leads to vasoconstriction and RAAS activity</p> Signup and view all the answers

    Which mediator is responsible for reducing circulating volume by stimulating natriuresis and diuresis?

    <p>Atrial natriuretic peptide (ANP)</p> Signup and view all the answers

    Which segment of the vascular system has lower pressure and vascular resistance compared to the systemic circuit?

    <p>Pulmonary circuit</p> Signup and view all the answers

    What is the most important biochemical mediator produced by endothelial cells and smooth muscle layers that promotes vasodilation, maintains vessel patency and vascular wall health, and lowers blood pressure?

    <p>Nitric oxide (NO)</p> Signup and view all the answers

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