10 Questions
What is the primary role of the red blood cells in the Ag-Ab reaction?
To act as antigens
What happens to the reactivity of properly stored red cells?
It improves
What is the purpose of washing red cells repeatedly?
To get rid of plasma containing fibrinogen
What is the typical storage location of antibodies?
In the serum
What is the optimal temperature range for IgM antibodies?
4-25°C, known as 'cold' antibody
What is the average incubation time for the Ag-Ab reaction?
60 minutes
What is the effect of LISS (Low-ionic strength solution) on the Ag-Ab reaction?
It increases the rate of antibody uptake
What is the optimal pH range for the Ag-Ab reaction?
6.5-7.5
What is the purpose of having a dilute solution of cells in the Ag-Ab reaction?
To ensure proper saturation of antigen sites with antibody molecules
What is the effect of the negative electric charge (zeta potential) of erythrocytes?
It keeps the cells apart
This quiz covers the main blood group systems, including Lewis, I, P, MNS, Kell, Kidd, and Duffy, and their clinical significance in transfusion reactions and hemolytic disease of newborn.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
