Blood Group Systems and Transfusion Reactions
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Questions and Answers

What is the primary role of the red blood cells in the Ag-Ab reaction?

  • To provide antibodies
  • To facilitate incubation
  • To store fibrinogen
  • To act as antigens (correct)
  • What happens to the reactivity of properly stored red cells?

  • It improves (correct)
  • It decreases
  • It remains the same
  • It becomes unpredictable
  • What is the purpose of washing red cells repeatedly?

  • To change the pH of the blood
  • To increase the ionic strength
  • To remove excess antibodies
  • To get rid of plasma containing fibrinogen (correct)
  • What is the typical storage location of antibodies?

    <p>In the serum</p> Signup and view all the answers

    What is the optimal temperature range for IgM antibodies?

    <p>4-25°C, known as 'cold' antibody</p> Signup and view all the answers

    What is the average incubation time for the Ag-Ab reaction?

    <p>60 minutes</p> Signup and view all the answers

    What is the effect of LISS (Low-ionic strength solution) on the Ag-Ab reaction?

    <p>It increases the rate of antibody uptake</p> Signup and view all the answers

    What is the optimal pH range for the Ag-Ab reaction?

    <p>6.5-7.5</p> Signup and view all the answers

    What is the purpose of having a dilute solution of cells in the Ag-Ab reaction?

    <p>To ensure proper saturation of antigen sites with antibody molecules</p> Signup and view all the answers

    What is the effect of the negative electric charge (zeta potential) of erythrocytes?

    <p>It keeps the cells apart</p> Signup and view all the answers

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