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Rh Antigens and Blood Transfusion

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Questions and Answers

What is the name of the small integral trans-membrane protein that carries the Vel antigen?

SMIM2

HLA-B7

SMIM1 (correct)

Tamm-Horsfall

What is the effect of anti-Vel on hemoglobin concentration?

Decreases hemoglobin concentration

Influences the mean hemoglobin concentration (correct)

Has no effect on hemoglobin concentration

Increases hemoglobin concentration

Which antigen is resistant to enzyme treatment and has a null phenotype common among Japanese?

Jra (correct)

Sda

Ata

Vel

What is the characteristic of anti-Sda agglutinates under the microscope?

Shiny and refractile Signup and view all the answers

Where is the Sda antigen not expressed in newborns?

RBCs Signup and view all the answers

What is the effect of anti-Ata on hemolytic transfusion reactions?

Severe reactions Signup and view all the answers

What is the origin of the Ata antigen?

From serum of black woman, Mrs. Augustine Signup and view all the answers

What is the characteristic of Bg antibodies?

Not considered clinically significant Signup and view all the answers

What is the target of anti-Bga?

Human Leukocyte Antigen (HLA)-B7 Signup and view all the answers

What is the effect of enzyme-treated RBCs on anti-Vel?

Enhances reaction Signup and view all the answers