Blood Group Determination
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Questions and Answers

What happens when Rh (-) mother and Rh (+) father's baby receives Rh (+) character from the father in the womb?

  • The mother's immune system becomes Rh (+) permanently.
  • Rh antigens are passed from the baby to the mother during the last months of pregnancy, especially during delivery. (correct)
  • The mother's immune system starts to produce anti-Rh antibodies immediately.
  • The baby's erythrocytes are constantly destroyed as a result of hemolysis.

How long can anti-Rh antibodies remain in the mother's circulation?

  • Two or three years (correct)
  • A few days
  • A few months
  • A few weeks

What happens to the erythrocytes of the second Rh (+) baby?

  • They increase in number
  • They become resistant to hemolysis
  • They mutate to Rh (-)
  • They are constantly destroyed as a result of hemolysis (correct)

Why is increased bilirubin level in babies a concern?

<p>It can easily pass into the brain tissue and cause irreversible damage (C)</p> Signup and view all the answers

When are drugs administered to prevent Rh incompatibility?

<p>Within the first 72 hours after birth of the first Rh (+) baby (A)</p> Signup and view all the answers

What is pulse?

<p>The pressure exerted by the heartbeats on the arteries from certain parts of the body (B)</p> Signup and view all the answers

What is tension in the context of blood pressure?

<p>The pressure exerted by the blood on the artery walls with each beat of the heart (C)</p> Signup and view all the answers

What does systolic blood pressure measure?

<p>The force your heart exerts on the walls of your arteries each time it beats (C)</p> Signup and view all the answers

Which of these is the correct definition of diastolic blood pressure?

<p>The force your heart exerts on the walls of your arteries in between beats. (B)</p> Signup and view all the answers

What instrument is used for indirect measurement of arterial blood pressure?

<p>Sphygmomanometer (C)</p> Signup and view all the answers

How is the cuff inflated during the blood pressure measurement?

<p>To 30 mmHg above the systolic pressure (C)</p> Signup and view all the answers

What is the mechanism behind the sounds heard during blood pressure measurement?

<p>The sound of turbulent blood flow in the brachial artery (A)</p> Signup and view all the answers

What happens to the blood flow in the brachial artery when the cuff pressure is reduced to systolic pressure?

<p>Blood flow resumes, but it is turbulent and noisy (A)</p> Signup and view all the answers

What does the disappearance of the sounds during blood pressure measurement indicate?

<p>The cuff pressure is equal to the diastolic pressure (C)</p> Signup and view all the answers

What is the general donor blood group that can give blood to other groups?

<p>O group (C)</p> Signup and view all the answers

Which blood group can receive blood from all other groups?

<p>AB group (C)</p> Signup and view all the answers

What is the Rh factor's distinction compared to A and B agglutinogens?

<p>It has no natural antibodies. (C)</p> Signup and view all the answers

Which of the following is a potential consequence of incompatible blood transfusions?

<p>Hemolytic transfusion reactions (C)</p> Signup and view all the answers

What occurs when a person with blood group A receives blood from a group B donor?

<p>Agglutination and hemolysis. (C)</p> Signup and view all the answers

What percentage of people are Rh positive?

<p>80% (A)</p> Signup and view all the answers

What clinical condition can arise due to incompatibility of blood groups in terms of Rh antigen during pregnancy?

<p>Erythroblastosis fetalis (C)</p> Signup and view all the answers

What happens when Rh- individuals receive Rh+ blood?

<p>Antibody formation against the Rh antigen (B)</p> Signup and view all the answers

Which blood group contains both A and B agglutinogens?

<p>Group AB (C)</p> Signup and view all the answers

What are the antibodies present in the plasma of a person with blood group B?

<p>Anti-A (B)</p> Signup and view all the answers

What is the main reason why agglutinogens are crucial in blood grouping?

<p>They provide antigenic properties to erythrocytes. (C)</p> Signup and view all the answers

What happens when Anti-A agglutinin encounters erythrocytes carrying the A agglutinogen?

<p>The erythrocytes clump together and undergo hemolysis. (C)</p> Signup and view all the answers

Which blood group lacks both A and B agglutinogens?

<p>Group 0 (A)</p> Signup and view all the answers

What is the general rule regarding the presence of agglutinins in the plasma?

<p>A person has agglutinins against the antigen they do not carry in their erythrocytes. (D)</p> Signup and view all the answers

What are the antibodies present in the plasma of a person with blood group AB?

<p>No antibodies (A)</p> Signup and view all the answers

What is the scientific term for the antibodies found in blood plasma that react with the A and B agglutinogens?

<p>Agglutinins (B)</p> Signup and view all the answers

Flashcards

Agglutinogens

Glycoproteins found on the surface of red blood cells (erythrocytes) that determine blood type.

ABO Blood Group System

A blood group system that categorizes individuals based on the presence or absence of A and B agglutinogens on red blood cells.

Agglutinins

Antibodies found in blood plasma that react with specific agglutinogens on red blood cells.

Blood Type AB

Individuals with both A and B agglutinogens on their red blood cells.

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Blood Type O

Individuals with neither A nor B agglutinogens on their red blood cells.

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Rh Factor

Antigenic structure found on erythrocyte membranes, separate from the ABO blood group system.

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Rh Positive (Rh+)

Individuals who possess the Rh antigen on their red blood cells.

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Rh Negative (Rh-)

Individuals who lack the Rh antigen on their red blood cells.

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Hemolytic Transfusion Reaction

A severe reaction that occurs when incompatible blood types are mixed.

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Hemolytic Disease of the Newborn (Erythroblastosis Fetalis)

A potentially fatal condition in newborns where the mother's immune system attacks the baby's red blood cells.

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Pulse

The rhythmic pressure wave created by the pumping action of the heart, felt in arteries.

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Blood Pressure

The pressure exerted by the blood against the walls of arteries.

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Systolic Blood Pressure

The pressure measured during the contraction of the heart ventricles.

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Diastolic Blood Pressure

The pressure measured between heartbeats, when the ventricles are relaxed.

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Hypertension

An abnormally high blood pressure.

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Sphygmomanometer

A device used to measure blood pressure.

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Korotkoff Sounds

The sounds heard through a stethoscope during blood pressure measurement, caused by turbulent blood flow.

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Laminar Flow

Smooth, continuous blood flow in arteries.

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Turbulent Flow

Irregular, chaotic blood flow in arteries.

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mmHg (Millimeters of Mercury)

The standard unit for measuring blood pressure, 1 mmHg = 1 millimeter of mercury.

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Universal Donor

A characteristic of blood type O, lacking A and B agglutinogens, making it compatible with all blood types in transfusion.

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Universal Recipient

A characteristic of blood type AB, containing both A and B agglutinogens, making it able to receive blood from all blood types.

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Blood Type Incompatibility

The antigen-antibody reaction that occurs during blood transfusions when incompatible blood types are mixed.

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Blood Transfusion

The process of transferring blood from one individual to another.

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Rh Incompatibility

A condition caused by Rh incompatibility between a pregnant woman and her fetus, leading to hemolytic disease of the newborn.

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Antibody Formation

The process of forming antibodies in the blood, often triggered by exposure to foreign antigens.

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Anemia

A condition which prevents the proper delivery of oxygen to the body due to insufficient production of healthy red blood cells.

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Antigen

A substance that triggers the formation of an antibody.

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Antibody

A protein that is produced by the body's immune system to fight infection.

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Study Notes

Determination of Blood Groups

  • Glycoprotein molecules in erythrocyte membranes give them antigenic properties, classified into A and B agglutinogens.
  • People are grouped according to their blood based on the presence of A and/or B agglutinogens: A, B, AB, and 0.
  • Antibodies that can react with antigenic A and B agglutinogens are naturally found in blood plasma, called agglutinins (Anti-A and Anti-B).
  • A person has agglutinin in their plasma against the antigen they do not carry in their erythrocytes.
  • Group 0, lacking A and B agglutinogens, is the general donor blood group, but can only receive blood from its own group.
  • AB group, carrying both agglutinogens, is the general receiver, can take blood from all groups, but only in limited quantities and under controlled conditions.

Rh Factor

  • Rh factor is another antigenic structure found in erythrocyte membranes.
  • If a person carries the Rh antigen, they are Rh (+), if not, they are Rh (-), with 80% of people being Rh (+).
  • The Rh antigen has no natural antibody, and antibody formation occurs when an Rh (-) person receives blood from an Rh (+) person.
  • Rh factor is important in blood transfusions, as incompatibility can cause hemolytic transfusion reactions.

Blood Transfusions

  • Blood types are crucial in blood transfusions to prevent hemolytic transfusion reactions.
  • A reaction occurs when the recipient's blood contains agglutinins against agglutinogens in the donor's erythrocytes.
  • Hemolytic disease of the newborn (erythroblastosis fetalis) occurs when an Rh (-) mother and Rh (+) father have a baby, and the mother's immune system produces anti-Rh antibodies.

Pulse and Blood Pressure

  • Pulse is the feeling of pressure exerted by heartbeats on arteries from certain parts of the body.
  • Blood pressure is the pressure exerted by the blood on artery walls with each heartbeat.
  • Systolic blood pressure measures the force the heart exerts on artery walls with each beat, while diastolic blood pressure measures the force between beats.
  • Hypertension is another name for high blood pressure.
  • Indirect measurement of arterial blood pressure is done using a sphygmomanometer and stethoscope.
  • The mechanism of sounds during measurement is caused by turbulent flow in the brachial artery, with laminar flow being quiet and turbulent flow being noisy.
  • Arterial pressure is expressed as systolic / diastolic pressure, e.g., 120/75 mmHg.

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Blood Groups PDF

Description

Learn about the classification of blood groups based on agglutinogens in erythrocyte membranes. Understand the basis of blood grouping and its importance.

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