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Blood Composition and Collection

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Questions and Answers

What is the effect of inflammation on fibrinogen formation?

Variable

No effect

Decrease

Increase (correct)

What is the role of calcium in clot formation?

Synthesis of prothrombin and fibrinogen

Conversion of inactive prothrombin to active prothrombin

Activation of coagulation factors (correct)

Production of bile

What is the role of the liver in clot formation?

Synthesis of prothrombin and fibrinogen (correct)

Conversion of fibrinogen to fibrin

Activation of platelets

Synthesis of vitamin K

What is the role of vitamin K in clot formation?

Conversion of inactive prothrombin to active prothrombin Signup and view all the answers

What is the first step in the extrinsic pathway?

TF (thromboplastin) + factor VII Signup and view all the answers

What is the role of thrombin in clot formation?

Conversion of fibrinogen to fibrin Signup and view all the answers

What is the effect of liver disease on fibrinogen formation?

Decrease Signup and view all the answers

What is the role of factor XII in clot formation?

Contact activation pathway Signup and view all the answers

What is the final step in clot formation?

Stabilization of the fibrin clot Signup and view all the answers

What is the role of tissue factor in clot formation?

Formation of TF:VIIa complex Signup and view all the answers