Blood Components & Digestion: Study Notes

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Questions and Answers

What is plasma?

Liquid component of blood, 55% of volume.

What are erythrocytes?

Red blood cells, 99% of cellular components.

What are leukocytes?

White blood cells, less than 1% of components.

What are platelets?

<p>Cell fragments crucial for blood clotting.</p> Signup and view all the answers

What is erythropoiesis?

<p>Production of red blood cells in bone marrow.</p> Signup and view all the answers

What is Erythropoietin (EPO)?

<p>Hormone stimulating erythropoiesis, produced by kidneys.</p> Signup and view all the answers

What is hemostasis?

<p>Process of blood clotting to prevent bleeding.</p> Signup and view all the answers

What is the role of iron in blood?

<p>Essential for hemoglobin synthesis during erythropoiesis.</p> Signup and view all the answers

What is the role of Vitamin B12 in blood?

<p>Necessary for red blood cell production, prevents anemia.</p> Signup and view all the answers

What is the role of Folic Acid in blood?

<p>Vitamin aiding in red blood cell formation.</p> Signup and view all the answers

What is Oxyhemoglobin?

<p>Hemoglobin bound to oxygen for transport.</p> Signup and view all the answers

What is Carbaminohemoglobin?

<p>Hemoglobin bound to carbon dioxide.</p> Signup and view all the answers

What is Bilirubin?

<p>Product of hemoglobin breakdown, excreted in bile.</p> Signup and view all the answers

What is Iron-deficiency Anemia?

<p>Most common type of anemia due to low iron.</p> Signup and view all the answers

What is Pernicious Anemia?

<p>Anemia caused by lack of vitamin B12.</p> Signup and view all the answers

What is Sickle Cell Anemia?

<p>Genetic disorder affecting red blood cell shape.</p> Signup and view all the answers

What are Agranulocytes?

<p>Type of leukocytes without visible granules.</p> Signup and view all the answers

What are Neutrophils?

<p>Most abundant leukocytes, respond to bacteria.</p> Signup and view all the answers

What is Vascular Spasm?

<p>Initial phase of hemostasis, blood vessel constriction.</p> Signup and view all the answers

What is Platelet Plug Formation?

<p>Second phase of hemostasis, aggregation of platelets.</p> Signup and view all the answers

What is Coagulation?

<p>Final phase of hemostasis, formation of a blood clot.</p> Signup and view all the answers

What is the purpose of vascular spasm?

<p>Blood vessels constrict to reduce blood loss.</p> Signup and view all the answers

What is the Endothelium?

<p>Inner lining of blood vessels.</p> Signup and view all the answers

What are Endothelins?

<p>Peptides that cause blood vessel constriction.</p> Signup and view all the answers

What is Von Willebrand Factor?

<p>Binds collagen and platelets for clotting.</p> Signup and view all the answers

What is Adenosine Diphosphate?

<p>Increases platelet stickiness during clotting.</p> Signup and view all the answers

What is Platelet Factor 3 (PF-3)?

<p>Essential for blood coagulation process.</p> Signup and view all the answers

What is Clotting Factor XII?

<p>Also known as Hageman Factor, initiates clotting.</p> Signup and view all the answers

What is Thromboxane A2?

<p>Promotes platelet aggregation and vasoconstriction.</p> Signup and view all the answers

What effect does Cox-1 have on blood?

<p>Enzyme that enhances platelet stickiness.</p> Signup and view all the answers

How is the Intrinsic Pathway activated?

<p>Activated by exposed collagen fibers.</p> Signup and view all the answers

What factor does the Common Pathway involve in clotting?

<p>Involves Factor X in clotting.</p> Signup and view all the answers

What is the role of Vitamin K in clotting?

<p>Essential for synthesizing clotting factors II, VII, IX, X.</p> Signup and view all the answers

What is another name for Factor III?

<p>Also known as tissue factor.</p> Signup and view all the answers

What are Anticoagulants?

<p>Substances that prevent blood clotting.</p> Signup and view all the answers

What produces thromboxane?

<p>Aspirin prevents thromboxane production.</p> Signup and view all the answers

How does Coumadin prevent clotting

<p>Prevents vitamin K utilization in clotting.</p> Signup and view all the answers

How does Sodium Citrate prevent clotting?

<p>Binds calcium to prevent clotting.</p> Signup and view all the answers

How does EDTA prevent blood coagulation?

<p>Binds calcium to prevent blood coagulation.</p> Signup and view all the answers

How does Heparin prevent clotting?

<p>Inhibits prothrombin activation to prevent clotting.</p> Signup and view all the answers

What are Agglutinogens?

<p>Antigens on red blood cell surfaces.</p> Signup and view all the answers

What antibodies does Blood Type A have in plasma?

<p>Has anti-B antibodies in plasma.</p> Signup and view all the answers

What antibodies does Blood Type O have?

<p>Has both anti-A and anti-B antibodies.</p> Signup and view all the answers

What does the Digestive System include?

<p>Includes organs for food digestion and absorption.</p> Signup and view all the answers

What function does the Mouth serve in digestion?

<p>Site of mechanical digestion and starch breakdown.</p> Signup and view all the answers

What function does the Esophagus serve in digestion?

<p>Conducts food via peristalsis to stomach.</p> Signup and view all the answers

What function does the Small Intestine serve in digestion?

<p>Primary site for nutrient absorption.</p> Signup and view all the answers

What is the Large Intestine responsible for?

<p>Responsible for waste removal and water absorption.</p> Signup and view all the answers

What are the Accessory Organs?

<p>Liver, pancreas, gallbladder aid in digestion.</p> Signup and view all the answers

What is Bile?

<p>Produced by liver, stored in gallbladder.</p> Signup and view all the answers

What function does the Gallbladder serve in digestion?

<p>Stores bile for digestion.</p> Signup and view all the answers

What function does the Pancreas serve in digestion?

<p>Produces hormones and digestive enzymes.</p> Signup and view all the answers

What is Hepatopancreatic sphincter responsible for?

<p>Regulates flow from pancreas and gallbladder.</p> Signup and view all the answers

What is Cystic Duct responsible for?

<p>Connects gallbladder to bile duct.</p> Signup and view all the answers

What is the function of the Maltase enzyme?

<p>Enzyme breaking maltose into glucose.</p> Signup and view all the answers

What does Sucrose split into?

<p>Sugar split into fructose and glucose.</p> Signup and view all the answers

What is the function of the Carboxypeptidase enzyme?

<p>Pancreatic enzyme digesting proteins.</p> Signup and view all the answers

What is the function of the Trypsin enzyme?

<p>Pancreatic enzyme for protein digestion.</p> Signup and view all the answers

What purpose does the Chymotrypsin enzyme serve?

<p>Pancreatic enzyme breaking down proteins.</p> Signup and view all the answers

What is the function of the Salivary Amylase enzyme?

<p>Enzyme initiating starch digestion in saliva.</p> Signup and view all the answers

What is the function of the Pancreatic Amylase enzyme?

<p>Converts starch to maltose in small intestine.</p> Signup and view all the answers

What function does Sodium Bicarbonate serve in the body?

<p>Neutralizes stomach acid in small intestine.</p> Signup and view all the answers

What function does Gastrin serve in the body?

<p>Hormone stimulating gastric acid secretion.</p> Signup and view all the answers

What function does Cholecystokinin (CCK) have in the body?

<p>Hormone triggering bile release from gallbladder.</p> Signup and view all the answers

What function does Secretin have?

<p>Stimulates pancreatic buffer secretion.</p> Signup and view all the answers

What function does Vasoactive Intestinal Peptide serve?

<p>Promotes capillary dilation near small intestine.</p> Signup and view all the answers

What function does Glucose Insulinotropic Peptide serve?

<p>Stimulates insulin release from pancreas.</p> Signup and view all the answers

What is the normal range for MAP (Mean Arterial Pressure)?

<p>Normal range: 70-110 mmHg.</p> Signup and view all the answers

What is the normal range for EF (Ejection Fraction)?

<p>Normal range: 55-70%.</p> Signup and view all the answers

What is the normal range for CO (Cardiac Output)?

<p>Normal range: 4-8 L/min.</p> Signup and view all the answers

What are Anabolic Reactions?

<p>Building up processes requiring energy.</p> Signup and view all the answers

What is Glycolysis?

<p>Produces ATP in cytosol.</p> Signup and view all the answers

What does Krebs Cycle produce?

<p>Produces ATP, FADH2, NADH in mitochondria.</p> Signup and view all the answers

Define platelets.

<p>Cell fragments crucial for blood clotting.</p> Signup and view all the answers

Why is iron important for red blood cell production?

<p>Essential for hemoglobin synthesis during erythropoiesis.</p> Signup and view all the answers

Why is vitamin B12 important for red blood cell production?

<p>Necessary for red blood cell production, prevents anemia.</p> Signup and view all the answers

Why is Folic Acid important for red blood cell production?

<p>Vitamin aiding in red blood cell formation.</p> Signup and view all the answers

Define carbaminohemoglobin.

<p>Hemoglobin bound to carbon dioxide.</p> Signup and view all the answers

Define Sickle Cell Anemia.

<p>Genetic disorder affecting red blood cell shape.</p> Signup and view all the answers

Define agranulocytes.

<p>Type of leukocytes without visible granules.</p> Signup and view all the answers

What do Eosinophils target?

<p>Leukocytes that target parasites and allergens.</p> Signup and view all the answers

Describe basophils.

<p>Least common leukocytes, involved in allergic responses.</p> Signup and view all the answers

What leukocytes respond to viral infections?

<p>Leukocytes that respond to viral infections.</p> Signup and view all the answers

What do monocytes differentiate into?

<p>Leukocytes that differentiate into macrophages.</p> Signup and view all the answers

What physiological process occurs during the vascular spasm phase of hemostasis?

<p>Initial phase of hemostasis, blood vessel constriction.</p> Signup and view all the answers

What occurs during the platelet plug formation phase of hemostasis?

<p>Second phase of hemostasis, aggregation of platelets.</p> Signup and view all the answers

Describe the Coagulation phase of hemostasis.

<p>Final phase of hemostasis, formation of a blood clot.</p> Signup and view all the answers

Define endothelium.

<p>Inner lining of blood vessels.</p> Signup and view all the answers

What is the role of endothelins in hemostasis?

<p>Peptides that cause blood vessel constriction.</p> Signup and view all the answers

What is the role of Adenosine Diphosphate in hemostasis?

<p>Increases platelet stickiness during clotting.</p> Signup and view all the answers

Clotting Factor XII is also known as what?

<p>Also known as Hageman Factor, initiates clotting.</p> Signup and view all the answers

The Intrinsic Pathway is activated by what?

<p>Activated by exposed collagen fibers.</p> Signup and view all the answers

Which factor is involved in the Common Pathway of coagulation?

<p>Involves Factor X in clotting.</p> Signup and view all the answers

What activates the Extrinsic Pathway??

<p>Activated by tissue damage, involves Factor III.</p> Signup and view all the answers

Which clotting factors require Vitamin K for synthesis?

<p>Essential for synthesizing clotting factors II, VII, IX, X.</p> Signup and view all the answers

What is Factor IIa also know as?

<p>Active form of Prothrombin, known as Thrombin.</p> Signup and view all the answers

Define anticoagulants.

<p>Substances that prevent blood clotting.</p> Signup and view all the answers

Explain how Cox-1 Inhibitors act as an anticogulant.

<p>Aspirin prevents thromboxane production.</p> Signup and view all the answers

What is the role of Coumadin?

<p>Prevents vitamin K utilization in clotting.</p> Signup and view all the answers

What is the role of Sodium Citrate?

<p>Binds calcium to prevent clotting.</p> Signup and view all the answers

What is the role of EDTA?

<p>Binds calcium to prevent blood coagulation.</p> Signup and view all the answers

How does Heparin work?

<p>Inhibits prothrombin activation to prevent clotting.</p> Signup and view all the answers

Define agglutinogens

<p>Antigens on red blood cell surfaces.</p> Signup and view all the answers

What does Blood Type A blood have in its plasma?

<p>Has anti-B antibodies in plasma.</p> Signup and view all the answers

What antibodies does Blood Type AB blood have in its plasma?

<p>Has no antibodies in plasma.</p> Signup and view all the answers

What is the digestive system?

<p>Includes organs for food digestion and absorption.</p> Signup and view all the answers

What is the Mouths role in digestion?

<p>Site of mechanical digestion and starch breakdown.</p> Signup and view all the answers

What is the Esophagus's role in digestion?

<p>Conducts food via peristalsis to stomach.</p> Signup and view all the answers

What is the Stomach's role in digestion?

<p>Secretes acids and enzymes for protein digestion.</p> Signup and view all the answers

What is the Small Intestines role in digestion?

<p>Primary site for nutrient absorption.</p> Signup and view all the answers

Which organs are the Accessory Organs?

<p>Liver, pancreas, gallbladder aid in digestion.</p> Signup and view all the answers

Explain the role of Bile in digestion.

<p>Produced by liver, stored in gallbladder.</p> Signup and view all the answers

What is the role of the Gallbladder?

<p>Stores bile for digestion.</p> Signup and view all the answers

What is the function of the Pancreas in digestion?

<p>Produces hormones and digestive enzymes.</p> Signup and view all the answers

What is the role of the Hepatopancreatic sphincter?

<p>Regulates flow from pancreas and gallbladder.</p> Signup and view all the answers

What is the role of the Cystic Duct?

<p>Connects gallbladder to bile duct.</p> Signup and view all the answers

What does Maltase break down?

<p>Enzyme breaking maltose into glucose.</p> Signup and view all the answers

What does Lactase digest?

<p>Enzyme digesting lactose into glucose and galactose.</p> Signup and view all the answers

What does Carboxypeptidase digest?

<p>Pancreatic enzyme digesting proteins.</p> Signup and view all the answers

What is the role of Trypsin?

<p>Pancreatic enzyme for protein digestion.</p> Signup and view all the answers

What does Salivary Amylase do?

<p>Enzyme initiating starch digestion in saliva.</p> Signup and view all the answers

What does Pancreatic Amylase do?

<p>Converts starch to maltose in small intestine.</p> Signup and view all the answers

What is the role of Sodium Bicarbonate in the intestine?

<p>Neutralizes stomach acid in small intestine.</p> Signup and view all the answers

What is Gastrin's role in the digestion process?

<p>Hormone stimulating gastric acid secretion.</p> Signup and view all the answers

What is the role of Cholecystokinin (CCK)?

<p>Hormone triggering bile release from gallbladder.</p> Signup and view all the answers

What's the function of Secretin?

<p>Stimulates pancreatic buffer secretion.</p> Signup and view all the answers

What is the role of Vasoactive Intestinal Peptide?

<p>Promotes capillary dilation near small intestine.</p> Signup and view all the answers

What is the role of Glucose Insulinotropic Peptide?

<p>Stimulates insulin release from pancreas.</p> Signup and view all the answers

Define Peristalsis.

<p>Wave-like muscle contractions moving food.</p> Signup and view all the answers

Define Anabolic Reactions.

<p>Building up processes requiring energy.</p> Signup and view all the answers

What is the purpose of Catabolic Reactions?

<p>Breaking down processes releasing energy.</p> Signup and view all the answers

Where does Glycolysis produce ATP?

<p>Produces ATP in cytosol.</p> Signup and view all the answers

Where does the Krebs Cycle produce ATP, FADH2, NADH?

<p>Produces ATP, FADH2, NADH in mitochondria.</p> Signup and view all the answers

What component of blood makes up 55% of its volume?

<p>Plasma</p> Signup and view all the answers

What is another name for red blood cells, which make up 99% of the cellular components of blood?

<p>Erythrocytes</p> Signup and view all the answers

Which blood cells are known as white blood cells and make up less than 1% of blood components?

<p>Leukocytes</p> Signup and view all the answers

What cell fragments are essential for blood clotting?

<p>Platelets</p> Signup and view all the answers

What is the term for the production of red blood cells in bone marrow?

<p>Erythropoiesis</p> Signup and view all the answers

Which hormone, produced by the kidneys, stimulates erythropoiesis?

<p>Erythropoietin (EPO)</p> Signup and view all the answers

What is the process of blood clotting to prevent bleeding called?

<p>Hemostasis</p> Signup and view all the answers

Which mineral is essential for hemoglobin synthesis during erythropoiesis?

<p>Iron</p> Signup and view all the answers

Which vitamin is necessary for red blood cell production and prevents anemia?

<p>Vitamin B12</p> Signup and view all the answers

Which vitamin aids in red blood cell formation?

<p>Folic Acid</p> Signup and view all the answers

What is the name of the protein in erythrocytes that binds oxygen?

<p>Hemoglobin</p> Signup and view all the answers

What is the term for hemoglobin bound to oxygen for transport?

<p>Oxyhemoglobin</p> Signup and view all the answers

What is the term for hemoglobin bound to carbon dioxide?

<p>Carbaminohemoglobin</p> Signup and view all the answers

What is the product of hemoglobin breakdown that is excreted in bile?

<p>Bilirubin</p> Signup and view all the answers

What is the condition of reduced red blood cell count called?

<p>Anemia</p> Signup and view all the answers

What is the most common type of anemia, caused by low iron?

<p>Iron-deficiency Anemia</p> Signup and view all the answers

What type of anemia is caused by a lack of vitamin B12?

<p>Pernicious Anemia</p> Signup and view all the answers

What is the genetic disorder that affects red blood cell shape called?

<p>Sickle Cell Anemia</p> Signup and view all the answers

What type of leukocytes have granules in their cytoplasm?

<p>Granulocytes</p> Signup and view all the answers

What type of leukocytes lack visible granules?

<p>Agranulocytes</p> Signup and view all the answers

Which are the most abundant leukocytes that respond to bacteria?

<p>Neutrophils</p> Signup and view all the answers

Which leukocytes target parasites and allergens?

<p>Eosinophils</p> Signup and view all the answers

Which are the least common leukocytes, involved in allergic responses?

<p>Basophils</p> Signup and view all the answers

Which leukocytes differentiate into macrophages?

<p>Monocytes</p> Signup and view all the answers

What is the initial phase of hemostasis, characterized by blood vessel constriction?

<p>Vascular Spasm</p> Signup and view all the answers

What is the second phase of hemostasis, involving the aggregation of platelets?

<p>Platelet Plug Formation</p> Signup and view all the answers

What is the final phase of hemostasis, leading to the formation of a blood clot?

<p>Coagulation</p> Signup and view all the answers

During vascular spasm, what do blood vessels do to reduce blood loss?

<p>Constrict</p> Signup and view all the answers

What is the inner lining of blood vessels called?

<p>Endothelium</p> Signup and view all the answers

What are the peptides that cause blood vessel constriction called?

<p>Endothelins</p> Signup and view all the answers

Which factor binds collagen and platelets for clotting?

<p>Von Willebrand Factor</p> Signup and view all the answers

Which molecule increases platelet stickiness during clotting?

<p>Adenosine Diphosphate</p> Signup and view all the answers

Which platelet factor is essential for the blood coagulation process?

<p>Platelet Factor 3 (PF-3)</p> Signup and view all the answers

Which clotting factor, also known as Hageman Factor, initiates clotting?

<p>Clotting Factor XII</p> Signup and view all the answers

Which molecule promotes platelet aggregation and vasoconstriction?

<p>Thromboxane A2</p> Signup and view all the answers

Which enzyme enhances platelet stickiness?

<p>Cox-1</p> Signup and view all the answers

Which pathway is activated by exposed collagen fibers?

<p>Intrinsic Pathway</p> Signup and view all the answers

Which pathway involves Factor X in clotting?

<p>Common Pathway</p> Signup and view all the answers

Which pathway is activated by tissue damage and involves Factor III?

<p>Extrinsic Pathway</p> Signup and view all the answers

Which vitamin is essential for synthesizing clotting factors II, VII, IX, and X?

<p>Vitamin K</p> Signup and view all the answers

What is the active form of Prothrombin known as?

<p>Thrombin</p> Signup and view all the answers

What is the active form of Fibrinogen known as?

<p>Fibrin</p> Signup and view all the answers

What are substances that prevent blood clotting called?

<p>Anticoagulants</p> Signup and view all the answers

How does aspirin act as a Cox-1 Inhibitor to prevent thromboxane production?

<p>Prevents thromboxane production</p> Signup and view all the answers

What is the function of Coumadin in the context of blood clotting?

<p>Prevents vitamin K utilization in clotting</p> Signup and view all the answers

How does Heparin work to prevent clotting?

<p>Inhibits prothrombin activation to prevent clotting</p> Signup and view all the answers

What are antigens on red blood cell surfaces called?

<p>Agglutinogens</p> Signup and view all the answers

What are antibodies in plasma that react with agglutinogens called?

<p>Agglutinins</p> Signup and view all the answers

Which antibodies are found in the plasma of individuals with Blood Type A?

<p>Anti-B antibodies</p> Signup and view all the answers

What is the function of the Digestive System?

<p>Includes organs for food digestion and absorption</p> Signup and view all the answers

What occurs in the mouth during digestion?

<p>Site of mechanical digestion and starch breakdown</p> Signup and view all the answers

What is the role of the Esophagus in digestion?

<p>Conducts food via peristalsis to stomach</p> Signup and view all the answers

What digestive processes occur in the Stomach?

<p>Secretes acids and enzymes for protein digestion</p> Signup and view all the answers

What is the primary function of the Small Intestine in digestion?

<p>Primary site for nutrient absorption</p> Signup and view all the answers

What roles does the Large Intestine play in digestion?

<p>Responsible for waste removal and water absorption</p> Signup and view all the answers

Which organs in the digestive system are considered Accessory Organs?

<p>Liver, pancreas, gallbladder aid in digestion</p> Signup and view all the answers

What role does Bile play in digestion?

<p>Produced by liver, stored in gallbladder</p> Signup and view all the answers

What is the function of the Gallbladder within the digestive system?

<p>Stores bile for digestion</p> Signup and view all the answers

What products are produced by the Pancreas that assist in digestion?

<p>Produces hormones and digestive enzymes</p> Signup and view all the answers

What is the function of the Hepatopancreatic sphincter?

<p>Regulates flow from pancreas and gallbladder</p> Signup and view all the answers

What does the Cystic Duct connect?

<p>Connects gallbladder to bile duct</p> Signup and view all the answers

What reaction does the enzyme Maltase catalyze?

<p>Enzyme breaking maltose into glucose</p> Signup and view all the answers

What products result from breaking down Sucrose?

<p>Sugar split into fructose and glucose</p> Signup and view all the answers

What process is carried out by the enzyme Lactase?

<p>Enzyme digesting lactose into glucose and galactose</p> Signup and view all the answers

What molecules does the enzyme Peptidase digest?

<p>Enzyme that digests polypeptides</p> Signup and view all the answers

Which substance is digested by Carboxypeptidase?

<p>Pancreatic enzyme digesting proteins</p> Signup and view all the answers

What role does Trypsin play in the digestive system?

<p>Pancreatic enzyme for protein digestion</p> Signup and view all the answers

Which molecules are broken down by the enzyme Chymotrypsin?

<p>Pancreatic enzyme breaking down proteins</p> Signup and view all the answers

What process does Salivary Amylase initiate?

<p>Enzyme initiating starch digestion in saliva</p> Signup and view all the answers

Which conversion is catalyzed by Pancreatic Amylase?

<p>Converts starch to maltose in small intestine</p> Signup and view all the answers

The enzyme Lipase is responsible for the digestion of which type of molecule?

<p>Enzyme that digests lipids</p> Signup and view all the answers

What function does Sodium Bicarbonate perform in digestion?

<p>Neutralizes stomach acid in small intestine</p> Signup and view all the answers

What digestive process is stimulated by the hormone Gastrin?

<p>Hormone stimulating gastric acid secretion</p> Signup and view all the answers

What is stimulated by the hormone Cholecystokinin (CCK)?

<p>Hormone triggering bile release from gallbladder</p> Signup and view all the answers

What process is stimulated by the hormone Secretin?

<p>Stimulates pancreatic buffer secretion</p> Signup and view all the answers

What effect is produced by Vasoactive Intestinal Peptide?

<p>Promotes capillary dilation near small intestine</p> Signup and view all the answers

What process is stimulated by Glucose Insulinotropic Peptide?

<p>Stimulates insulin release from pancreas</p> Signup and view all the answers

What is the nature of Peristalsis?

<p>Wave-like muscle contractions moving food</p> Signup and view all the answers

What is regarded as a normal range for MAP (Mean Arterial Pressure)?

<p>Normal range: 70-110 mmHg</p> Signup and view all the answers

What is considered a normal range for EF (Ejection Fraction)?

<p>Normal range: 55-70%</p> Signup and view all the answers

What are the Normal values for CO (Cardiac Output)?

<p>Normal range: 4-8 L/min</p> Signup and view all the answers

What occurs during Anabolic Reactions?

<p>Building up processes requiring energy</p> Signup and view all the answers

What process accompanies Glycolysis?

<p>Produces ATP in cytosol</p> Signup and view all the answers

What is produced during Krebs Cycle?

<p>Produces ATP, FADH2, NADH in mitochondria</p> Signup and view all the answers

Flashcards

Plasma

Liquid component of blood, 55% of volume.

Erythrocytes

Red blood cells, 99% of cellular components.

Leukocytes

White blood cells, less than 1% of components.

Platelets

Cell fragments crucial for blood clotting.

Signup and view all the flashcards

Erythropoiesis

Production of red blood cells in bone marrow.

Signup and view all the flashcards

Erythropoietin (EPO)

Hormone stimulating erythropoiesis, produced by kidneys.

Signup and view all the flashcards

Hemostasis

Process of blood clotting to prevent bleeding.

Signup and view all the flashcards

Iron

Essential for hemoglobin synthesis during erythropoiesis.

Signup and view all the flashcards

Vitamin B12

Necessary for red blood cell production, prevents anemia.

Signup and view all the flashcards

Folic Acid

Vitamin aiding in red blood cell formation.

Signup and view all the flashcards

Hemoglobin

Protein in erythrocytes that binds oxygen.

Signup and view all the flashcards

Oxyhemoglobin

Hemoglobin bound to oxygen for transport.

Signup and view all the flashcards

Carbaminohemoglobin

Hemoglobin bound to carbon dioxide.

Signup and view all the flashcards

Carboxyhemoglobin

Hemoglobin bound to carbon monoxide.

Signup and view all the flashcards

Bilirubin

Product of hemoglobin breakdown, excreted in bile.

Signup and view all the flashcards

Anemia

Condition of reduced red blood cell count.

Signup and view all the flashcards

Iron-deficiency Anemia

Most common type of anemia due to low iron.

Signup and view all the flashcards

Pernicious Anemia

Anemia caused by lack of vitamin B12.

Signup and view all the flashcards

Sickle Cell Anemia

Genetic disorder affecting red blood cell shape.

Signup and view all the flashcards

Granulocytes

Type of leukocytes with granules in cytoplasm.

Signup and view all the flashcards

Vascular Spasm

Blood vessels constrict to reduce blood loss.

Signup and view all the flashcards

Endothelium

Inner lining of blood vessels.

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Vitamin K

Essential for synthesizing clotting factors II, VII, IX, X.

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Factor II

Also known as Prothrombin, precursor to thrombin.

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Anticoagulants

Substances that prevent blood clotting.

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Agglutinogens

Antigens on red blood cell surfaces.

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Agglutinins

Antibodies in plasma that react with agglutinogens.

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Blood Type A

Has anti-B antibodies in plasma.

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Blood Type B

Has anti-A antibodies in plasma.

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Blood Type AB

Has no antibodies in plasma.

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Blood Type O

Has both anti-A and anti-B antibodies.

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Study Notes

  • Study notes on blood components, erythrocytes, and digestion including key functions, definitions, and normal ranges.

Blood Components and Erythrocytes

  • Plasma is the liquid component of blood, making up 55% of its total volume.
  • Erythrocytes, or red blood cells, constitute 99% of the blood's cellular components.
  • Leukocytes, known as white blood cells, account for less than 1% of blood components.
  • Platelets are cell fragments essential for blood clotting.
  • Erythropoiesis is the production of red blood cells, occurring in bone marrow.
  • Erythropoietin (EPO), a hormone produced by the kidneys, stimulates erythropoiesis.
  • Hemostasis is the process of blood clotting that prevents bleeding.
  • Iron is essential for hemoglobin synthesis during erythropoiesis.
  • Vitamin B12 prevents anemia and is necessary for red blood cell production.
  • Folic acid is a vitamin that aids in the formation of red blood cells.
  • Hemoglobin is a protein in erythrocytes that binds oxygen for transport.
  • Oxyhemoglobin is hemoglobin bound to oxygen to facilitate oxygen transport.
  • Carbaminohemoglobin is hemoglobin bound to carbon dioxide.
  • Carboxyhemoglobin is hemoglobin bound to carbon monoxide.
  • Bilirubin is a product of hemoglobin breakdown and is excreted in bile.
  • Anemia is a condition characterized by a reduced red blood cell count.
  • Iron-deficiency anemia, the most common type, results from low iron levels.
  • Pernicious anemia is caused by a deficiency in vitamin B12.
  • Sickle cell anemia is a genetic disorder affecting the shape of red blood cells.
  • Granulocytes are a type of leukocyte containing granules in their cytoplasm.
  • Agranulocytes are leukocytes that lack visible granules.
  • Neutrophils are the most abundant leukocytes and respond to bacterial infections.
  • Eosinophils are leukocytes that target parasites and allergens.
  • Basophils, the least common leukocytes, are involved in allergic responses.
  • Lymphocytes are leukocytes that respond to viral infections.
  • Monocytes are leukocytes that differentiate into macrophages.

Hemostasis and Clotting Factors

  • Vascular spasm is the initial phase of hemostasis, involving blood vessel constriction.
  • Platelet plug formation is the second phase, characterized by platelet aggregation.
  • Coagulation is the final phase of hemostasis, resulting in the formation of a blood clot.
  • Endothelium is the inner lining of blood vessels.
  • Endothelins are peptides causing blood vessel constriction.
  • Von Willebrand Factor binds collagen and platelets to facilitate clotting.
  • Adenosine Diphosphate increases platelet stickiness during clotting.
  • Platelet Factor 3 (PF-3) is essential for blood coagulation.
  • Clotting Factor XII, also known as Hageman Factor, initiates clotting.
  • Thromboxane A2 promotes platelet aggregation and vasoconstriction.
  • Cox-1 is an enzyme that enhances platelet stickiness.
  • The intrinsic pathway for clotting is activated by exposed collagen fibers.
  • The common pathway involves Factor X in the clotting process.
  • The extrinsic pathway is activated by tissue damage and involves Factor III.
  • Vitamin K is essential for synthesizing clotting factors II, VII, IX, and X.
  • Factor III, also known as tissue factor, initiates the extrinsic pathway.
  • Factor VII is also known as Proconvertin.
  • Factor X is also known as Stuart-Power Factor.
  • Factor XI is also known as Antihemophilic Factor C.
  • Factor IX is also known as Christmas Factor.
  • Factor II is also known as Prothrombin, acts as a precursor to thrombin.
  • Factor IIa is the active form of Prothrombin, known as Thrombin.
  • Factor XIII is also known as Fibrin Stabilizing Factor.
  • Factor I, also known as Fibrinogen, a precursor to fibrin.
  • Factor Ia is the active form of Fibrinogen, known as Fibrin.

Anticoagulants and Blood Types

  • Anticoagulants are substances that prevent blood clotting.
  • Cox-1 inhibitors, like aspirin, prevent thromboxane production.
  • Coumadin prevents vitamin K utilization in clotting.
  • Sodium Citrate prevents clotting by binding calcium.
  • EDTA prevents blood coagulation by binding calcium.
  • Heparin inhibits prothrombin activation to prevent clotting.
  • Agglutinogens are antigens present on red blood cell surfaces.
  • Agglutinins are antibodies in plasma that react with agglutinogens.
  • Blood Type A has anti-B antibodies in plasma.
  • Blood Type B has anti-A antibodies in plasma.
  • Blood Type AB has no antibodies in plasma.
  • Blood Type O has both anti-A and anti-B antibodies.

Digestive System Overview

  • The digestive system includes organs responsible for food digestion and absorption.
  • The mouth is the site of mechanical digestion and starch breakdown.
  • The esophagus transports food via peristalsis to the stomach.
  • The stomach secretes acids and enzymes for protein digestion.
  • The small intestine is the primary site for nutrient absorption.
  • The large intestine is responsible for waste removal and water absorption.
  • Accessory organs, including the liver, pancreas, and gallbladder, aid in digestion.
  • The liver produces bile, which is stored in the gallbladder.
  • The gallbladder stores bile for digestion.
  • The pancreas produces hormones and digestive enzymes.
  • The hepatopancreatic sphincter regulates the flow from the pancreas and gallbladder.
  • The cystic duct connects the gallbladder to the bile duct.

Digestive Enzymes

  • Maltase is the enzyme breaking maltose into glucose.
  • Sucrase splits sucrose into fructose and glucose
  • Lactase digests lactose into glucose and galactose.
  • Peptidase is an enzyme that digests polypeptides.
  • Carboxypeptidase is a pancreatic enzyme that digests proteins.
  • Trypsin is a pancreatic enzyme for protein digestion.
  • Chymotrypsin is a pancreatic enzyme breaking down proteins.
  • Salivary Amylase is an enzyme initiating starch digestion in saliva.
  • Pancreatic Amylase converts starch to maltose in the small intestine.
  • Lipase digests lipids.

Digestive Hormones

  • Sodium Bicarbonate neutralizes stomach acid in the small intestine.
  • Gastrin stimulates gastric acid secretion.
  • Cholecystokinin (CCK) triggers bile release from the gallbladder.
  • Secretin stimulates pancreatic buffer secretion.
  • Vasoactive Intestinal Peptide promotes capillary dilation near the small intestine.
  • Glucose Insulinotropic Peptide stimulates insulin release from the pancreas.

Physiological Processes

  • Peristalsis is the wave-like muscle contractions that moves food through the digestive tract.
  • Normal Mean Arterial Pressure (MAP) range: 70-110 mmHg.
  • Normal Ejection Fraction (EF) range: 55-70%.
  • Normal Cardiac Output (CO) range: 4-8 L/min.
  • Anabolic reactions are building-up processes requiring energy.
  • Catabolic reactions are breaking-down processes releasing energy.
  • Glycolysis produces ATP in the cytosol.
  • The Krebs Cycle produces ATP, FADH2, and NADH in the mitochondria.

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