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Questions and Answers
Match the components of blood with their functions:
Match the components of blood with their functions:
Erythrocytes = Transport oxygen and carbon dioxide Leukocytes = Immune response Platelets = Blood clotting Plasma = Transportation of nutrients and waste
Match the types of anemia with their causes:
Match the types of anemia with their causes:
Iron-deficiency anemia = Dietary deficiencies of iron Vitamin B12 anemia = Dietary deficiency of vitamin B12 Hemorrhagic anemia = Blood loss from the body Aplastic anemia = Bone marrow failure
Match the types of globulins with their functions:
Match the types of globulins with their functions:
Alpha & Beta globulins = Transport proteins for lipids Gamma globulins = Antibodies for immune response Fibrinogen = Blood clot formation Albumin = Maintaining oncotic pressure
Match the following blood characteristics with their descriptions:
Match the following blood characteristics with their descriptions:
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Match the following types of polycythemia with their descriptions:
Match the following types of polycythemia with their descriptions:
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Match the following elements with their corresponding blood components:
Match the following elements with their corresponding blood components:
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Match the terms related to erythropoiesis with their meanings:
Match the terms related to erythropoiesis with their meanings:
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Match the following hemoglobin characteristics with their values:
Match the following hemoglobin characteristics with their values:
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Match the functions of blood with their descriptions:
Match the functions of blood with their descriptions:
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Match the components of blood with their characteristics:
Match the components of blood with their characteristics:
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Match the following blood components with their primary characteristics:
Match the following blood components with their primary characteristics:
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Match the components of plasma with their main contents:
Match the components of plasma with their main contents:
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Match the following white blood cells with their types:
Match the following white blood cells with their types:
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Match the characteristics of blood with the appropriate categories:
Match the characteristics of blood with the appropriate categories:
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Match the following blood groups with their characteristics:
Match the following blood groups with their characteristics:
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Match the following conditions with their effects:
Match the following conditions with their effects:
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Match the terms related to blood with their definitions:
Match the terms related to blood with their definitions:
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Match the blood types with their antigen characteristics:
Match the blood types with their antigen characteristics:
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Match the following characteristics with the corresponding blood cell type:
Match the following characteristics with the corresponding blood cell type:
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Match the type of blood cell with its primary function:
Match the type of blood cell with its primary function:
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Match the following terms with their definitions:
Match the following terms with their definitions:
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Match the following types of leukocytes with their functions:
Match the following types of leukocytes with their functions:
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Match the process titles with their functions:
Match the process titles with their functions:
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Match the following blood components with their place of formation:
Match the following blood components with their place of formation:
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Match the blood group with its ability to give and receive blood:
Match the blood group with its ability to give and receive blood:
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Match the Rh blood type with its description:
Match the Rh blood type with its description:
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Match the following blood groups with their respective antigens:
Match the following blood groups with their respective antigens:
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Match the blood group with its universal donor or recipient status:
Match the blood group with its universal donor or recipient status:
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Match the term with its definition:
Match the term with its definition:
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Match the discovery with its origin:
Match the discovery with its origin:
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Match the blood group with its corresponding antibodies:
Match the blood group with its corresponding antibodies:
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Match the Rh blood type with its compatibility for transfusion:
Match the Rh blood type with its compatibility for transfusion:
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Study Notes
Functions of Blood
- Transports oxygen, nutrients, metabolic wastes, hormones, enzymes, and processed molecules throughout the body.
- Regulates osmosis, pH, and body temperature.
- Protects against excessive loss (hemostasis) and disease through white blood cells, phagocytosis, antibodies, and other mechanisms.
Composition of Blood
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Plasma:
- Separated from blood by a coagulant and centrifugation.
- Over 90% water.
- Contains clotting proteins.
- Fresh plasma is straw-colored.
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Serum:
- Cell-free fluid decanted from clotted blood.
- Lacks clotting proteins.
Composition of Plasma
- Water (approximately 90%).
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Solutes:
- Nutrients, gases, hormones, wastes and products of cell activity, proteins, and inorganic ions (electrolytes).
- Electrolytes (Na+, Cl-, etc.) are the most abundant solutes.
Plasma Proteins
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Albumin (60% of plasma proteins):
- Main contributor to osmotic pressure.
- Produced by the liver.
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Globulins (36% of plasma proteins):
- Alpha & Beta: produced by the liver, most are transport proteins that bind to lipids, metal ions, and fat-soluble vitamins.
- Gamma: antibodies released by plasma cells during an immune response.
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Fibrinogen (4% of plasma proteins):
- Produced by the liver.
- Forms fibrin threads of a blood clot.
Formed Elements of Blood
- Erythrocytes (red blood cells).
- Leukocytes (white blood cells).
- Platelets (thrombocytes).
Red Blood Cells (Erythrocytes)
- Erythropoiesis: production of red blood cells.
- Erythropoietin: hormone produced by the kidneys in response to low blood oxygen levels, stimulates red blood cell production in red bone marrow.
- Lifespan: approximately 120 days.
- Average RBC count: 5,500,000 cells/mm3 of blood.
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Function:
- Transport oxygen from the lungs to tissues.
- Help transport carbon dioxide from tissues to the lungs.
- Hematocrit: proportion of blood occupied by red blood cells (40-45%).
- Hemoglobin (iron protein): found in red blood cells, consists of four polypeptide chains.
- Normal hemoglobin levels: 16 g/dl for men and 14 g/dl for women.
- Function of Hemoglobin: carries oxygen and carbon dioxide between the lungs and body cells.
- Bilirubin: major breakdown product of hemoglobin.
Anemia
- Definition: low number of red blood cells, low hemoglobin, or low hematocrit.
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Classification by Cause:
- Dietary deficiencies of iron (iron-deficiency anemia), vitamin B12, or folic acid.
- Bone marrow failure due to toxic drugs or cancer.
- Blood loss from the body (hemorrhage).
- Inadequate secretion of erythropoietin in kidney disease.
- Excessive destruction of erythrocytes (e.g. sickle cell disease).
Polycythemia
- Definition: abnormal excess of erythrocytes, increases blood viscosity.
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Types:
-
Physiological Polycythemia:
- Occurs in natives living at high altitudes where atmospheric oxygen is low.
- Blood count is generally 6-7 million/mm3.
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Secondary Polycythemia (Polycythemia Vera):
- Pathologic condition in bone marrow cancer.
- Characterized by dizziness and exceptionally high RBC count (8-11 million cells/μl).
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Physiological Polycythemia:
White Blood Cells (Leukocytes)
- Largest-sized blood cells.
- Lowest numbers in the blood: 4,500 – 11,000 per microliter.
- Formed in bone marrow and some in lymph glands.
- Primary cells of the immune system.
- Fight disease and foreign invaders.
- Lifespan ranges from 24 hours to several years.
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Types:
-
Granular Leukocytes:
- Neutrophils
- Eosinophils
- Basophils
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Agranular Leukocytes:
- Lymphocytes (T cells, B cells, natural killer cells)
- Monocytes
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Granular Leukocytes:
Platelets (Thrombocytes)
- Formed in the bone marrow.
- Smallest of the blood cells.
- Count: 150,000 – 400,000/ mm3.
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Functions:
- Involved in the clotting process.
- Seal wounds and prevent blood loss.
- Help repair damaged vessels.
- Half-life: 8-12 days.
- Storage: 30% stored in the spleen.
- Splenectomy: leads to an increase in platelet count (thrombocytosis).
Hemostasis
- Definition: prevents blood loss.
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Process:
- Vascular spasm: constricts the blood vessel.
- Platelet plug formation: platelets adhere to the damaged area.
- Blood clotting: fibrin threads form a clot to seal the wound.
Blood Grouping
- ABO blood groups: based on the presence or absence of two agglutinogens: type A and type B.
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Blood types:
- Type A: has type A antigen and anti-B antibodies.
- Type B: has type B antigen and anti-A antibodies.
- Type AB: has both antigens and neither A or B antibodies (universal receivers).
- Type O: has neither antigens, but possesses both anti-A and anti-B antibodies (universal donors).
- Agglutinins (Antibodies): antibodies that act against RBCs carrying ABO antigens that are not present on a person's own red blood cells.
- Development of Antibodies: antibodies do not normally develop against an antigen unless the body is exposed to that antigen.
Rh Blood Group
- Named after the rhesus monkey.
- Rh-positive: individuals have certain Rh antigens on the surface of their red blood cells.
- Rh-negative: individuals lack these Rh antigens.
- Rh antibodies: do not develop unless an Rh-negative person is exposed to Rh-positive red blood cells.
- Rh incompatibility: can pose a problem during pregnancy if the mother is Rh-negative and the fetus is Rh-positive.
- Hemolytic Disease of the Newborn (HDN): can occur if the mother produces anti-Rh antibodies that can cross the placenta and destroy fetal red blood cells.
Mechanism of HDN
- Exposure of the mother to fetal Rh-positive blood through leakage across the placenta during pregnancy or delivery.
- Production of anti-Rh antibodies by the mother.
- Antibodies cross the placenta into the fetal blood during later pregnancies, resulting in HDN.
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Description
Test your knowledge on the various components of blood and their functions, including different types of anemia and their causes. This quiz will challenge you to match blood characteristics, globulins, and hemoglobin values with their corresponding descriptions and meanings. Ideal for students studying human biology or healthcare-related fields.