10 Questions
What is the primary function of endothelial cells in the context of haemostasis?
To secrete nitric oxide and prostaglandins
What is the effect of endothelial cell injury on smooth muscle cells?
Contraction
What is the purpose of the vascular spasm that occurs in response to endothelial injury?
To reduce blood flow to the damaged area
What protein is released by damaged endothelial cells that binds to collagen and promotes platelet adhesion?
Von Willebrand factor
What is the surface protein on platelets that allows them to bind to Von Willebrand factor?
GP1B
What is the primary function of platelets in haemostasis?
To adhere to damaged endothelial cells
What is the consequence of endothelial cell injury on nitric oxide and prostaglandin secretion?
Decreased secretion
What is the primary function of collagen in the context of haemostasis?
To provide a surface for platelet adhesion
What is the consequence of platelet adhesion to Von Willebrand factor?
Platelet activation and degranulation
What is the term for the sequence of events that leads to the formation of a blood clot?
Primary haemostasis
This quiz covers the fourth step in blood coagulation, where platelets bind to Von Willebrand factor, leading to platelet activation and the release of certain molecules.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
